發(fā)布時(shí)間：2018-02-28 23:06

  本文關(guān)鍵詞： 糖尿病 氣陰兩虛證 糖參樂(lè)丸 臨床觀察　出處：《湖北中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:本研究旨在通過(guò)臨床觀察糖參樂(lè)丸治療2型糖尿病(氣陰兩虛證)的臨床療效及其安全性,證明糖參樂(lè)丸是治療此類型糖尿病的有效藥物,為臨床治療該病提供一定參考依據(jù)。方法:收集2015年6月一2016年6月就診于荊州市中醫(yī)醫(yī)院內(nèi)分泌的78例氣陰兩虛型診斷為2型糖尿病患者,并將其隨機(jī)劃分為治療組和對(duì)照組,治療組39例,對(duì)照組39例,比較兩組患者的性別、年齡、病程、體質(zhì)指數(shù)、病情嚴(yán)重程度以及中醫(yī)證候總積分等各個(gè)方面,兩組并無(wú)明顯差異,具有可比性(P0.05)。對(duì)照組口服二甲雙胍緩釋片,每次0.5g,每日3次,飯后服用;治療組在上述治療基礎(chǔ)上加予口服糖參樂(lè)丸,每次6g,每日3次,飯前服用。兩組治療均以3個(gè)月為1個(gè)療程。觀察指標(biāo)為治療前后兩組患者的癥狀積分、空腹血糖及餐后2小時(shí)血糖、糖化血紅蛋白、血脂情況。結(jié)果:治療前后兩組患者的中醫(yī)癥狀總積分皆有顯著性差異(P0.05),且治療組療效優(yōu)于對(duì)照組(P0.05)。治療組總有效率為89.7%,對(duì)照組總有效率為74.4%,治療組的臨床總有效率亦高于對(duì)照組(P0.05)。治療組能夠明顯改善患者的口渴喜飲、倦怠乏力等主要癥狀,對(duì)多食善饑、多尿、氣短懶言等次要癥狀也有改善,且效果更優(yōu)于對(duì)照組。兩組患者在治療前后的主癥、次癥療效積分方面均有顯著的差別(P0.05)。兩組均能有效降低患者的空腹血糖及餐后2小時(shí)血糖、糖化血紅蛋白、血脂指標(biāo),統(tǒng)計(jì)結(jié)果顯示治療組的降低程度大于對(duì)照組(P0.05)。結(jié)論:本研究結(jié)果提示糖參樂(lè)丸能有效治療2型糖尿病(氣陰兩虛證),改善患者的臨床癥狀及相關(guān)實(shí)驗(yàn)室指標(biāo),其療效優(yōu)于西藥組,且價(jià)格適中,便于攜帶服用,為中醫(yī)中藥治療糖尿病提供了有效可行的方法。
[Abstract]:Objective: to observe the clinical efficacy and safety of Tangshenle Pill in the treatment of type 2 diabetes mellitus (deficiency of Qi and Yin), and to prove that Tangshenle Pill is an effective drug for the treatment of this type of diabetes. Methods: 78 cases of type 2 diabetes diagnosed by deficiency of Qi and Yin were collected from June 1st 2015 to June 2016 in Jingzhou Hospital of traditional Chinese Medicine. They were randomly divided into treatment group and control group, 39 cases in treatment group and 39 cases in control group. The sex, age, course of disease, body mass index, severity of illness and total score of TCM syndromes were compared between the two groups. There was no significant difference between the two groups (P 0.05). The control group took metformin sustained-release tablets at 0.5 g, 3 times a day, after meals. The treatment group was treated with Tangshenle pills, 6 g per day, 3 times a day, on the basis of the above treatment. Taken before meals. The two groups were treated with 3 months as a course of treatment. The observation indexes were the symptom score, fasting blood glucose, 2 hours postprandial blood glucose, glycosylated hemoglobin, and hemoglobin glycosylated in the two groups before and after treatment. Results: there were significant differences in the total scores of TCM symptoms between the two groups before and after treatment, and the curative effect of the treatment group was better than that of the control group (P 0.05). The total effective rate of the treatment group was 89.7%, the total effective rate of the control group was 74.4%, and the clinical efficacy of the treatment group was 74.4%. The efficiency of the treatment group was also higher than that of the control group (P 0.05). The main symptoms, such as burnout and fatigue, also improved the secondary symptoms, such as polyfood and hunger, polyuria, shortness of breath and lazy speech, and the effect was better than that of the control group. There were significant differences in the scores of the secondary symptoms (P 0.05). The fasting blood glucose, 2 hours postprandial blood glucose, glycosylated hemoglobin and blood lipid were significantly decreased in the two groups. The statistical results showed that the degree of decrease in the treatment group was greater than that in the control group (P 0.05). Conclusion: this study suggests that Tangshenle pills can effectively treat type 2 diabetes mellitus (qi and yin deficiency syndrome) and improve the clinical symptoms and related laboratory indexes of the patients. Its curative effect is superior to the western medicine group, and the price is moderate, easy to carry and take, which provides an effective and feasible method for the treatment of diabetes mellitus with traditional Chinese medicine.
【學(xué)位授予單位】：湖北中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R259

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