本文關(guān)鍵詞： 通腑化痰湯 卒中相關(guān)性肺炎 痰熱腑實證 臨床研究　出處：《山東中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:研究通腑化痰湯在治療卒中相關(guān)性肺炎中的臨床效果。方法:將入選的60例病例分為治療組和對照組,每組30例。予以對照組常規(guī)治療,治療組在常規(guī)治療基礎(chǔ)上加用通腑化痰湯口服或鼻飼。臨床試驗結(jié)束后觀察兩組患者臨床總有效率、中醫(yī)證候積分、CPIS評分、炎性指標(白細胞計數(shù)、C反應(yīng)蛋白、PCT)變化,并進行統(tǒng)計分析。結(jié)果:研究結(jié)果表明在臨床總有效率方面,治療組總有效率90%,對照組總有效率86.67%,兩組間對比具有統(tǒng)計學(xué)意義,說明在常規(guī)治療基礎(chǔ)上加用通腑化痰湯可以提高臨床總有效率。在降低中醫(yī)證候總積分方面治療組優(yōu)于對照組,兩組間差異具有統(tǒng)計學(xué)意義。對兩組患者治療后單項中醫(yī)證候積分進行組間比較,在便干便秘、腹脹積分方面治療組明顯優(yōu)于對照組(P0.01);在咳嗽、痰色、痰質(zhì)、喘促、尿黃、舌紅苔黃或灰黑而燥、脈洪數(shù)或滑數(shù)方面治療組優(yōu)于對照組(P0.05),兩組間差異具有統(tǒng)計學(xué)意義;在發(fā)熱、肺部體征、胸痛方面,兩組間差異無統(tǒng)計學(xué)意義(P0.05)。在降低CPIS評分方面治療組優(yōu)于對照組,兩組間差異具有統(tǒng)計學(xué)意義。兩組患者炎性指標于治療后進行組間比較,差異無統(tǒng)計學(xué)意義(P0.05)。這說明,治療組在改善炎性指標方面,與對照組療效大體相當。本臨床研究60例病例全部如期完成治療,無脫落、中止試驗。兩組患者血常規(guī)、尿常規(guī)、大便常規(guī)、肝功能、腎功能、心電圖檢查等安全性指標,均未發(fā)生異常變化。結(jié)論:通腑化痰湯聯(lián)合西醫(yī)常規(guī)治療可以提高卒中相關(guān)性肺炎總有效率,并可以改善患者部分臨床癥狀,且安全性較高。
[Abstract]:Objective: to study the clinical effect of Tongfu Huatan decoction (Tongfu Huatan decoction) in treating apoplexy associated pneumonia. Methods: 60 cases were divided into treatment group and control group with 30 cases in each group. The treatment group was treated with Tongfu Huatan decoction oral or nasal feeding on the basis of routine treatment. After the clinical trial, the total effective rate of the two groups, the CPIS score of TCM syndromes and the changes of inflammatory index (white blood cell count and C-reactive protein) were observed. Results: the results showed that the total effective rate of the treatment group was 90 and that of the control group was 86.67.The comparison between the two groups was statistically significant. It shows that the treatment group is superior to the control group in reducing the total integral of TCM syndromes by adding Tongfu Huatan decoction on the basis of routine treatment. The difference between the two groups was statistically significant. The scores of single TCM syndromes after treatment in the two groups were significantly better than those in the control group in terms of dry constipation and abdominal distension, cough, phlegm color, phlegm quality, shortness of breath, yellow urine. The treatment group was superior to the control group in terms of the number of vein and flood or slip, the difference was statistically significant in the aspects of fever, pulmonary signs, chest pain, and the difference between the two groups was statistically significant. There was no significant difference between the two groups (P 0.05). The treatment group was superior to the control group in reducing the CPIS score, and the difference between the two groups was statistically significant. The therapeutic effect of the treatment group in improving the inflammatory indexes was approximately the same as that of the control group. All 60 cases in this clinical study completed the treatment on schedule, without abscission or discontinuation of the test. The blood routine, urine routine, stool routine, liver function, renal function of the two groups of patients, Conclusion: Tongfu Huatan decoction combined with routine western medicine treatment can improve the total effective rate of stroke associated pneumonia, and can improve some clinical symptoms of patients, and the safety is high.
【學(xué)位授予單位】：山東中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R277.7

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