本文關(guān)鍵詞： 急性心肌梗死 熱毒證候 危險(xiǎn)因素 血脂代謝紊亂　出處：《中國實(shí)驗(yàn)方劑學(xué)雜志》2017年11期 　論文類型：期刊論文

【摘要】：目的:探討急性心肌梗死熱毒證患者的危險(xiǎn)因素,對(duì)其證候病因進(jìn)行分析。方法:回顧性篩選收集廣州中醫(yī)藥大學(xué)第一附屬醫(yī)院確診為急性心肌梗死患者的臨床資料,進(jìn)行中醫(yī)證候分布調(diào)查,并將其分為熱毒證組及非熱毒證組,分析兩組的一般資料以及住院病情預(yù)后,并采用Logistic回歸分析熱毒證病因的危險(xiǎn)因素。結(jié)果:研究納入322例患者中熱毒證組占42.20%(136例),非熱毒證組占57.8%(186例)。熱毒證組平均血管病變數(shù)、左室舒張末、左室射血分?jǐn)?shù)明顯差于非熱毒組(P0.05),住院期間心血管死亡例數(shù)兩組未見明顯差異。單因素分析熱毒證分布為吸煙、辛辣厚味飲食、糖尿病、高脂血癥多重心血管危險(xiǎn)因素聚集人群(P0.05),Logistic回歸分析發(fā)現(xiàn)吸煙、低密度脂蛋白、甘油三酯3個(gè)因子是預(yù)測熱毒證候病因的獨(dú)立要素,比值比(OR)分別為1.755,1.637,1.483。結(jié)論:急性心肌梗死熱毒證形成病因與吸煙、血脂代謝紊亂相關(guān),住院期間預(yù)后與非熱毒證未見差異,但心室重構(gòu)程度重于非熱毒證組。
[Abstract]:Objective: to investigate the risk factors of acute myocardial infarction with heat toxin syndrome and analyze the etiology of its syndrome. Methods: the clinical data of the patients diagnosed as acute myocardial infarction in the first affiliated Hospital of Guangzhou University of traditional Chinese Medicine were collected retrospectively. To investigate the distribution of TCM syndromes, and divide them into heat toxin syndrome group and non heat toxin syndrome group, and analyze the general data of the two groups and the prognosis of hospitalization. Logistic regression analysis was used to analyze the risk factors of heat toxin syndrome. Results: among 322 patients, heat toxin syndrome group accounted for 42. 20 cases and non-heat toxin syndrome group accounted for 57. 8%. The mean number of vascular lesions and left ventricular diastolic end in heat toxin syndrome group were 57.8%. The left ventricular ejection fraction (LVEF) was significantly lower than that in the non-heat toxic group (P 0.05). There was no significant difference in the number of cardiovascular deaths between the two groups during hospitalization. Logistic regression analysis showed that smoking, low density lipoprotein and triglyceride were independent factors in predicting the etiology of heat toxin syndrome. The ratio of ORs to OR was 1.7551.637and 1.483.Conclusion: the etiology of heat toxin syndrome in acute myocardial infarction is related to smoking, dyslipidemia, and the prognosis during hospitalization is not different from that of non-heat toxic syndrome, but the degree of ventricular remodeling is more serious than that of non-heat toxic syndrome.
【作者單位】： 廣州中醫(yī)藥大學(xué)第一附屬醫(yī)院;廣州中醫(yī)藥大學(xué);
【基金】：國家中醫(yī)臨床研究基地業(yè)務(wù)建設(shè)科研專項(xiàng)(JDZX2015241)
【分類號(hào)】：R259

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