本文關(guān)鍵詞： 帶狀皰疹 后遺神經(jīng)痛 肝經(jīng)郁熱型 臨床觀察　出處：《成都中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：本課題基于中醫(yī)“治未病”之“既病防變”理論及“辨證與辨病相結(jié)合”治療特色,評(píng)價(jià)“自擬活血止痛方”治療初期帶狀皰疹(肝經(jīng)郁熱型)的臨床療效及安全性,以及探索早期運(yùn)用活血化瘀通絡(luò)法對(duì)預(yù)防后遺神經(jīng)痛的療效,為臨床提供新思路。方法：將90名肝經(jīng)郁熱型帶狀皰疹患者隨機(jī)分為兩組,對(duì)照組予西藥常規(guī)治療,試驗(yàn)組在對(duì)照組用藥基礎(chǔ)上加用自擬活血止痛方干預(yù)治療。連續(xù)治療2周。于治療前及治療第3、7、10、14天以及治療后隨訪1月、2月、3月,通過(guò)病證評(píng)定指標(biāo)及VAS評(píng)分比較兩組間帶狀皰疹體征、疼痛程度以及后遺神經(jīng)痛發(fā)生率的差異,作出療效判定。結(jié)果：(1)綜合療效治療組有效率為79.55%,對(duì)照組有效率為72.09%,治療組與對(duì)照組療效相當(dāng)(P0.05)；改善疼痛療效治療組有效率84.09%,對(duì)照組65.12%；在改善疼痛療效方面,治療組均優(yōu)于對(duì)照組(P0.05)；(2)兩組在VAS評(píng)分方面,治療組優(yōu)于對(duì)照組(P0.05),即在改善疼痛方面,治療組優(yōu)于對(duì)照組；(3)兩組在改善皮損及疼痛程度方面,治療前后均有改善(P0.05)； (4)兩組在疼痛緩解50%、結(jié)痂面積達(dá)50%所需時(shí)間方面,治療組低于對(duì)照組(P0.05)；(5)在改善全身癥狀(中醫(yī)次癥)方面,治療組優(yōu)于對(duì)照組(P0.05)；(6)治療結(jié)束后1、2、3月隨訪,治療組發(fā)生后遺神經(jīng)痛的頻率低于對(duì)照組,差異有顯著性(P0.05)。結(jié)論：(1)“自擬活血止痛方”針對(duì)肝經(jīng)郁熱型帶狀皰疹療效明顯,對(duì)疼痛程度的改善尤為明顯。(2)對(duì)于肝經(jīng)郁熱型帶狀皰疹,早期運(yùn)用“自擬活血止痛方”預(yù)防后遺神經(jīng)痛的發(fā)生,療效確切、安全,具有臨床推廣性；(3)早期運(yùn)用活血化瘀通絡(luò)法治療肝經(jīng)郁熱型帶狀皰疹,對(duì)預(yù)防后遺神經(jīng)痛的發(fā)生起一定作用。
[Abstract]:Objective: this subject is based on the "disease prevention" theory and the treatment characteristics of "syndrome differentiation and disease differentiation". Objective: to evaluate the clinical efficacy and safety of "Huoxue Zhitong recipe" in the treatment of early herpes zoster (liver meridian stagnation and heat type), and to explore the effect of early application of Huoxue Huayu Tongluo method on the prevention of posthumous neuralgia. Methods: 90 patients with herpes zoster due to stagnation of liver meridian were randomly divided into two groups, the control group was treated with routine western medicine. The experimental group was treated with self-made Huoxue Zhitong prescription on the basis of the control group. The treatment lasted for 2 weeks, followed up on January, February, March before and after treatment. The difference of herpes zoster sign, pain degree and the incidence rate of sequelae neuralgia were compared between the two groups by the evaluation index of disease syndrome and VAS score. Results the effective rate of the comprehensive treatment group was 79.55 and that of the control group was 72.09. The curative effect of the treatment group was equal to that of the control group (P 0.05). The effective rate was 84.09 in the treatment group and 65.12 in the control group. In improving the curative effect of pain, the treatment group was better than the control group (P 0.05). 2) the VAS score of the two groups was better than that of the control group (P 0.05), that is, the treatment group was superior to the control group in improving the pain. 3) both groups improved the degree of skin lesion and pain before and after treatment (P 0.05). (4) the time of pain relief and scabbing area of 50% in the two groups was lower than that in the control group (P 0.05). 5) the treatment group was superior to the control group in improving the systemic symptoms. The frequency of posthepatitic neuralgia in the treatment group was lower than that in the control group. The difference was significant (P 0.05). Conclusion the "Self-made prescription for promoting Blood Circulation and Zhitong" is effective in treating herpes zoster with stagnation and heat of liver meridian. For herpes zoster with stagnation and heat of liver meridian, early application of "self-made prescription for activating blood circulation and Zhitong" to prevent the occurrence of sequelae neuralgia is effective, safe and has clinical popularization. 3) early treatment of herpes zoster with stagnation of liver meridian by activating blood circulation and removing blood stasis and dredging collaterals plays a certain role in preventing the occurrence of sequelae neuralgia.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R275.9

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 吳根鵬;朱為;;水痘-帶狀皰疹疫苗的使用現(xiàn)狀及研究進(jìn)展[J];中國(guó)生物制品學(xué)雜志;2016年03期

2 齊曉琳;宋業(yè)強(qiáng);;清熱止痛湯聯(lián)合刺絡(luò)放血拔罐治療帶狀皰疹后遺神經(jīng)痛臨床觀察[J];中醫(yī)藥臨床雜志;2016年01期

3 高鵬;吳龍海;;針刺聯(lián)合穴位注射治療帶狀皰疹后遺神經(jīng)痛的臨床療效分析[J];中國(guó)醫(yī)藥指南;2016年02期

4 王君明;郭曉娜;馮衛(wèi)生;張?jiān)略?崔瑛;;地黃多糖和寡糖的藥理作用研究進(jìn)展[J];中國(guó)老年學(xué)雜志;2015年22期

5 許恩宏;楊春曲;王立峰;;解毒活血湯加減治療老年帶狀皰疹后遺神經(jīng)痛的療效分析[J];臨床醫(yī)藥文獻(xiàn)電子雜志;2015年32期

6 張文海;;川芎的藥理作用及臨床應(yīng)用[J];中國(guó)衛(wèi)生標(biāo)準(zhǔn)管理;2015年26期

7 付紅菊;魏光蓉;柳研;;中藥熱熨治療帶狀皰疹后遺神經(jīng)痛療效觀察及護(hù)理[J];世界最新醫(yī)學(xué)信息文摘;2015年77期

8 杜天樂(lè);張學(xué)勇;景春暉;;中醫(yī)藥治療帶狀皰疹后遺神經(jīng)痛的研究進(jìn)展[J];湖南中醫(yī)雜志;2015年08期

9 周冬梅;陳維文;;蛇串瘡中醫(yī)診療指南(2014年修訂版)[J];中醫(yī)雜志;2015年13期

10 楊建剛;吳勝利;;龍膽瀉肝湯加減治療帶狀皰疹后遺神經(jīng)痛的臨床研究[J];上海醫(yī)藥;2015年12期

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