本文關(guān)鍵詞： 益腎清利法 尿路感染 反復(fù)發(fā)作 臨床研究　出處：《南京中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

【摘要】：目 的：通過觀察治療前后患者的主要癥狀及實(shí)驗(yàn)室指標(biāo)的變化,觀察益腎清利療法對緩解反復(fù)發(fā)作性尿路感染癥狀、改善相關(guān)實(shí)驗(yàn)室指標(biāo)及減少復(fù)發(fā)的影響,綜合評價(jià)該療法對反復(fù)發(fā)作性尿路感染(RUTI)的防治效果。方法：收入自2013年9月至2016年1月期間于江蘇省中醫(yī)院腎科、泌尿外科門診及病房的RUTI共90個(gè)病例患者。根據(jù)中醫(yī)辨證標(biāo)準(zhǔn)和RUTI診斷標(biāo)準(zhǔn)將患者分為氣陰兩虛和氣陽兩虛兩類,每一類分為治療組和對照組。氣陰兩虛類病例60例,其中1治療組40例,對照組20例：氣陽兩虛類病例30例,其中治療組、對照組分別20例、10例。對照組均根據(jù)藥敏結(jié)果應(yīng)用抗生素治療,治療組在它的基礎(chǔ)上再用益腎清利方,其中,對氣陰兩虛證采取益氣養(yǎng)陰,清利濕熱法治療,對氣陽兩虛證采取溫補(bǔ)脾腎,清利濕熱法治療,療程4周。共隨訪6個(gè)月以上。結(jié)果：1.對全部入組患者年齡分布情況統(tǒng)計(jì),入組患者均為女性,多集中在45-75年齡段。2.在中醫(yī)證候療效方面比較,兩類治療組痊愈率、顯效率均高于對照組,但總有效率兩組相當(dāng),無統(tǒng)計(jì)差異。其中,氣陰兩虛證治療組治療后,尿頻、尿急、尿痛或灼熱感、小腹脹痛癥狀均有極顯著改善(p0.01),對排尿不暢有顯著改善(p0.05)。與對照組比較,治療組在小便渾濁、口干咽干方面的改善優(yōu)于對照組,其他癥狀無顯著差異。氣陽兩虛證治療組全部癥狀具有極顯著改善(p0.01)；對照組中遇勞加劇、大便溏薄、乏力顯著改善(p0.05),尿頻數(shù)、排尿不暢極顯著改善(p0.01)。兩組療后積分比較,治療組遇勞加劇、畏寒怕冷癥狀積分顯著低于對照組(p0.05)。這表明治療組在改善尿頻數(shù)、排尿不暢方面與對照組療效相當(dāng),而腰部隱痛、大便溏薄、小腹墜脹、畏寒怕冷等氣陽兩虛癥狀的改善則顯著優(yōu)于對照組。3.治療組和對照組的尿白細(xì)胞計(jì)數(shù)降低極顯著(p0.01),治療組優(yōu)于對照組。4.隨訪6個(gè)月后,治療組復(fù)發(fā)率均低于對照組,氣陰兩虛證具有極顯著性差異(p0.01)。結(jié)論：益腎清利法治療反復(fù)發(fā)作性尿路感染具有很好的臨床療效,能顯著改善癥狀、降低實(shí)驗(yàn)室指標(biāo)、減少復(fù)發(fā)。
[Abstract]:By observing the changes of main symptoms and laboratory indexes before and after treatment, we observed the effects of Yishen Qingli therapy on relieving the symptoms of recurrent urinary tract infection, improving related laboratory indexes and reducing recurrence. Methods: from September 2013 to January 2016, the patients were enrolled in the Department of Kidney, Jiangsu Provincial Hospital of traditional Chinese Medicine. There were 90 cases of RUTI in urology clinic and ward. According to the criteria of TCM syndrome differentiation and RUTI diagnosis, the patients were divided into two categories: Qi and Yin deficiency and Qi and Yang deficiency, each of which was divided into treatment group and control group. There were 60 cases of Qi and Yin deficiency. There were 40 cases in the treatment group and 20 cases in the control group: 30 cases of deficiency of Qi and yang, of which 20 cases were treated with antibiotics in the treatment group and 20 cases in the control group. Among them, Qi-Yin deficiency syndrome is treated with the method of supplementing qi and nourishing yin, clearing away the dampness and heat, and treating the deficiency of qi and yang with the method of warming up the spleen and kidney, and clearing away the dampness and heat. The course of treatment was 4 weeks and followed up for more than 6 months. Results: 1.The age distribution of all the patients in the group was female, mostly in 45-75 age group .2.Compared with the curative effect of TCM syndromes, the recovery rate of the two treatment groups was higher than that of the control group. The effective rate was higher than that of the control group, but the total effective rate was the same between the two groups, and there was no statistical difference. The symptoms of flatulence in the lower abdomen were significantly improved (P 0.01), and the dysuria was significantly improved (P 0.05). Compared with the control group, the improvement of urine turbidity and dry mouth pharynx in the treatment group was better than that in the control group. There was no significant difference in other symptoms. All symptoms of Qi-Yang deficiency syndrome treatment group were significantly improved (P 0.01); in the control group, fatigue was aggravated, stool was thin, fatigue was significantly improved (p 0.05), frequency of urine, dysuria was significantly improved. After treatment, the scores of the two groups were compared. The scores of cold and cold symptoms in the treatment group were significantly lower than those in the control group (P 0.05). This indicated that the treatment group had the same curative effect as the control group in improving the frequency of urination and dysuria, but the pain in the waist, thin stools and distension of the lower abdomen. The improvement of qi and yang deficiency symptoms such as chilling and chilling was significantly better than that of control group .3.The urine white blood cell count in treatment group and control group was significantly lower than that in control group, and that in treatment group was better than that in control group .4.After 6 months follow-up, the recurrence rate in treatment group was lower than that in control group. Conclusion: Yishen Qingli method has a good clinical effect in treating recurrent urinary tract infection, it can significantly improve symptoms, reduce laboratory indexes and reduce recurrence.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R277.5

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 沈慶法;;清利法治療蛋白尿[J];上海中醫(yī)藥雜志;2006年02期

2 夏國守;繆界平;陳海燕;何映;;補(bǔ)腎清利法治療慢性非細(xì)菌性前列腺炎21例臨床觀察[J];江蘇中醫(yī)藥;2007年01期

3 葛緣仁;養(yǎng)陰清利法治療難治性腎病綜合征臨床觀察[J];上海中醫(yī)藥雜志;1999年09期

4 尹智功,黃玲;益脾腎法、清利法與益脾腎清利法治療慢性腎功能衰竭的比較研究[J];湖北中醫(yī)雜志;2004年12期

5 盛梅笑;張麗麗;李正紅;;益腎清利法治療慢性原發(fā)性腎小球疾病蛋白尿的療效觀察[J];遼寧中醫(yī)雜志;2011年05期

6 朱建紅;周偉進(jìn);李偉君;方芳;;活血清利法治療慢性潰瘍性結(jié)腸炎療效觀察[J];湖北中醫(yī)雜志;2008年08期

7 牟吉榮;劉普希;;疏通清利法治療膽囊炎154例[J];遼寧中醫(yī)雜志;1989年09期

8 劉大偉;;滋腎清利法治療狼瘡性腎炎蛋白尿臨床觀察[J];光明中醫(yī);2013年04期

9 朱賢旬;蘇益仁;鄒艷賢;;益腎清利法治療復(fù)發(fā)性尿路感染療效觀察[J];環(huán)球中醫(yī)藥;2013年S2期

10 王莉;陳霞;;滋腎清利法治療老年性陰道炎37例[J];陜西中醫(yī);2009年11期

相關(guān)會(huì)議論文 前5條

1 張永;韓寧;;滋陰清利法在失代償期肝硬化中的運(yùn)用[A];中華中醫(yī)藥學(xué)會(huì)第十二屆內(nèi)科肝膽病學(xué)術(shù)會(huì)議暨第四次國家中醫(yī)肝病重點(diǎn)�？茀f(xié)作組學(xué)術(shù)會(huì)議論文匯編[C];2006年

2 林燕;張乾;任桐;何永生;;活血清利法治療膜性腎病40例臨床觀察[A];中華中醫(yī)藥學(xué)會(huì)第二十一屆全國中醫(yī)腎病學(xué)術(shù)會(huì)議論文匯編（下）[C];2008年

3 林燕;張乾;任桐;何永生;;活血清利法為主治療膜性腎病的臨床研究[A];2008年全國中西醫(yī)結(jié)合腎臟病南京論壇論文匯編[C];2008年

4 宋躍飛;;滋腎清利法治療腎陰不足型輕度系膜增生性IgA腎病療效觀察[A];第七屆全國中西醫(yī)結(jié)合腎臟病會(huì)議論文匯編[C];2003年

5 胡海翔;劉宏偉;劉云海;時(shí)振聲;;滋陰益腎活血清利法在IgA腎病中的應(yīng)用與基礎(chǔ)研究[A];2004'中華中醫(yī)藥科技成果專輯[C];2004年

相關(guān)碩士學(xué)位論文 前10條

1 姜超娜;補(bǔ)腎清利法治療腎虛濕熱型慢性腎炎的臨床研究[D];山東中醫(yī)藥大學(xué);2015年

2 徐秀琴;益腎清利法治療反復(fù)發(fā)作性尿路感染的臨床療效觀察[D];南京中醫(yī)藥大學(xué);2016年

3 俞曼殊;益腎清利法治療慢性腎炎蛋白尿的療效觀察及對預(yù)后的影響[D];南京中醫(yī)藥大學(xué);2016年

4 夏國守;補(bǔ)腎清利法治療慢性非細(xì)菌性前列腺炎的臨床研究[D];南京中醫(yī)藥大學(xué);2005年

5 劉紅靜;滋腎清利法治療反復(fù)發(fā)作性尿路感染的臨床療效觀察[D];南京中醫(yī)藥大學(xué);2012年

6 張持萍;益腎清利法治療系膜增生性腎小球腎炎的臨床研究[D];南京中醫(yī)藥大學(xué);2010年

7 肖澤清;健脾益腎活血清利法治療慢性腎臟病3期的臨床觀察[D];南京中醫(yī)藥大學(xué);2010年

8 段倩;涼血化瘀、滋腎清利法防治小兒過敏性紫癜腎炎的臨床研究[D];南京中醫(yī)藥大學(xué);2008年

9 戴路明;養(yǎng)肝活血清利法治療失代償性肝硬化臨床研究[D];南京中醫(yī)藥大學(xué);2004年

10 王雅娟;補(bǔ)腎化瘀清利法配合超聲透入治療盆腔炎性疾病后遺癥腎虛瘀濁型的臨床療效觀察[D];南京中醫(yī)藥大學(xué);2010年

，

本文編號(hào)：1490439