發(fā)布時(shí)間：2018-01-25 02:37

  本文關(guān)鍵詞： 強(qiáng)直性脊柱炎 家系 流行特征 中醫(yī)體質(zhì) 遺傳 人類白細(xì)胞抗原B　出處：《中華中醫(yī)藥雜志》2017年12期 　論文類型：期刊論文

【摘要】：目的:對(duì)強(qiáng)直性脊柱炎家系進(jìn)行調(diào)查,以了解AS家系的發(fā)病特點(diǎn)和影響因素,分析AS發(fā)病的因素。方法:采用問(wèn)卷調(diào)查和臨床檢查,收集AS家系成員的社會(huì)人口學(xué)、生活習(xí)慣、臨床癥狀、中醫(yī)體質(zhì)等情況,進(jìn)行統(tǒng)計(jì)分析。結(jié)果:本研究共調(diào)查了34個(gè)強(qiáng)直性脊柱炎家系,共計(jì)254人,其中AS患者121例,健康者133人。AS患者的Ⅰ、Ⅱ、Ⅲ級(jí)親屬患病率分別為47.7%、43.1%、26.7%。AS患者中HLA-B27陽(yáng)性率以及偏頗體質(zhì)的比例明顯高于AS家系中的健康人。結(jié)論:AS為高度遺傳的自身免疫性疾病,其發(fā)病與HLA-B27相關(guān),AS患者中陽(yáng)虛和痰濕偏頗體質(zhì)的比例較高,但其與AS發(fā)生的因果關(guān)系有待進(jìn)一步論證。
[Abstract]:Objective: to investigate the family of ankylosing spondylitis in order to understand the characteristics and influencing factors of as family and analyze the factors of as. Methods: questionnaire survey and clinical examination were used. The social demography, living habits, clinical symptoms and TCM constitution of as family members were collected and analyzed. Results: a total of 34 families with ankylosing spondylitis were investigated in this study. Among them, 121 cases of as and 133 healthy persons. The prevalence rate of grade 鈪，

本文編號(hào)：1461753