本文關(guān)鍵詞： 太陰調(diào)胃湯加減 慢性胃炎 臨床研究　出處：《延邊大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:通過觀察朝醫(yī)太陰人方劑太陰調(diào)胃湯加減對太陰人慢性胃炎的朝醫(yī)臨床療效,為該方藥的臨床應(yīng)用提供更可靠的理論依據(jù)。方法:將2016年1月至2016年12月期間,在延邊朝醫(yī)醫(yī)院和延邊中醫(yī)醫(yī)院門診及療區(qū)就診收治的太陰人慢性胃炎的患者,隨機(jī)分為治療組30例和對照組各30例。兩組患者在性別、病程、病情、年歲上均無顯著性差異,(P0.05),具有可比性。治療組用太陰調(diào)胃湯加減湯劑(桔梗10g,薏苡仁15g,萊菔子10g,干栗15g,五味子5g,石菖蒲5g,白及10g,蠶砂10g麥門冬5g,)治療。用自動煎藥機(jī)水煎太陰調(diào)胃湯加減,真空袋包裝,每袋200ml,一次1袋,日2次口服。對照組用常規(guī)的西藥三聯(lián)治療方法:(1)泮托拉唑注射液60ml+生理鹽水250ml,每日1次,靜脈滴注。(2)阿莫西林片1g,每日2次,口服;克拉霉素片0.25mg,每日2次,口服。7天為1個療程,觀察2個療程。主要觀察兩組治療后的療效、兩組治療前后朝醫(yī)證候積分、兩組胃鏡檢查結(jié)果、兩組治療前后病理檢查結(jié)果、兩組治療前后HP檢查結(jié)果、安全性指標(biāo)觀察等。結(jié)果:兩組在給予藥物治療14天后,臨床效果比較顯示:治療組總有效率顯然明顯比對照組高,有顯著的差異(P0.05),具有統(tǒng)計學(xué)意義;兩組治療前,治療后的朝醫(yī)證候積分的比較示:治療組有效率明顯高于對照組,有顯著性差異(P0.05),有統(tǒng)計學(xué)意義;兩組胃鏡檢查結(jié)果顯示:治療組有效率明顯高于對照組;兩組治療前后病理檢查結(jié)果比較示:治療組很顯然明顯優(yōu)于對照組,有顯著性差異(P0.05),有統(tǒng)計學(xué)意義;治療組和對照組,治療前后HP檢查結(jié)果的比較示:治療組明顯優(yōu)于對照組,有顯著性差異(P0.05),有統(tǒng)計學(xué)意義;安全性指標(biāo)觀察兩組患者治療前后生命體征、血常規(guī)、尿常規(guī)、便常規(guī)、肝功能(ALT、AST)、腎功能(BUN、Cr、UA)及心電圖均正常。此外,在臨床觀察過程當(dāng)中,治療與對照兩組,均未發(fā)現(xiàn)不良反應(yīng)。結(jié)論:研究結(jié)果表明,朝醫(yī)方太陰調(diào)胃湯加減能有效的改善太陰人慢性胃炎的臨床癥狀,具有一定程度的胃粘膜修復(fù)作用。
[Abstract]:Objective: to observe the clinical effect of Taiyin Tiaowei decoction on chronic gastritis of Taiyin. To provide a more reliable theoretical basis for the clinical application of the prescription. Methods: from January 2016 to December 2016. The patients with chronic gastritis of Taiyin were randomly divided into treatment group (n = 30) and control group (n = 30). The treatment group was treated with Taiyin Tiaowei decoction (10g of Platycodon, 15g of Coix seed, 10g of semen Raphani, 15g of dried Chestnut). Treatment of Schisandra chinensis 5g, Acorus calamus 5g, white and 10g, silkworm sand 10g. Decoction of Taiyin and stomach with automatic decoction machine, vacuum bag packing, 200 ml per bag, 1 bag once. The control group was treated with routine western medicine treatment method: 1) pam Tora injection 60ml normal saline 250ml, once a day, iv. 2) amoxicillin tablet 1g. 2 times a day, orally; Clarithromycin tablets 0.25 mg, twice a day, oral 7 days as a course of treatment, observe two courses of treatment. The main observation of the two groups after treatment, the two groups before and after treatment before and after the integration of the Korean medical syndrome, the results of two groups of gastroscopy. The results of pathological examination before and after treatment, the results of HP examination before and after treatment in both groups, the observation of safety indexes, etc. Results: after 14 days of drug therapy, the two groups were treated with drugs. The comparison of clinical results showed that the total effective rate of the treatment group was obviously higher than that of the control group, and there was a significant difference between the treatment group and the control group (P 0.05). The comparison of syndrome score before and after treatment in the two groups showed that the effective rate in the treatment group was significantly higher than that in the control group with significant difference (P 0.05). The results of gastroscopy in the two groups showed that the effective rate of the treatment group was significantly higher than that of the control group; The results of pathological examination before and after treatment in the two groups showed that the treatment group was obviously superior to the control group, with a significant difference (P 0.05). The results of HP examination in the treatment group and the control group before and after treatment showed that the treatment group was obviously superior to the control group, with a significant difference (P 0.05). Safety indexes were observed before and after treatment of vital signs, blood routine, urine routine, routine routine, liver function of alt ASTU, renal function BUNA Cr UAA) and electrocardiogram were normal. In the course of clinical observation, no adverse reactions were found in the treatment and control groups. Conclusion: the results of the study show that the clinical symptoms of chronic gastritis of Taiyin people can be effectively improved by Taiyin Tiaowei decoction. It can repair gastric mucosa to a certain extent.
【學(xué)位授予單位】：延邊大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R259
，

本文編號：1453128