本文關(guān)鍵詞：針刺結(jié)合五苓湯加減治療強直性脊柱炎的臨床研究　出處：《中國中醫(yī)基礎(chǔ)醫(yī)學雜志》2017年08期 　論文類型：期刊論文

  更多相關(guān)文章： 針刺 五苓湯加減 強直性脊柱炎 臨床研究

【摘要】：目的:觀察針刺結(jié)合五苓湯加減治療強直性脊柱炎的療效及安全性。方法:將108例強直性脊柱炎患者按隨機數(shù)字表法分為西藥組、中藥組和針藥組各36例。西藥組給予柳氮磺吡啶片,中藥組給予五苓湯加減,針藥組給予針刺結(jié)合五苓湯加減,療程均為60 d,觀察各組患者治療前后總和指數(shù)(BAS-G)、活動性指數(shù)(BASDAI)、放射學指數(shù)(BASRI)、活動度衡量指數(shù)(BASMI)和中醫(yī)辨證強直性脊柱炎(中醫(yī)證候)的評分,檢測治療前后血沉(ESR)、C-反應(yīng)蛋白(CRP)、甲狀旁腺激素(PHI)和補體3(C_3)的變化,比較各組臨床療效及不良反應(yīng)發(fā)生率。結(jié)果:治療后針藥組總有效率71.4%,優(yōu)于西藥組的58.1%和中藥組的52.8%,針藥組各評分均較西藥組和中藥組改善更為顯著,針藥組和中藥組不良反應(yīng)發(fā)生率低于西藥組。結(jié)論:針刺結(jié)合五苓湯加減可顯著提高強直性脊柱炎患者BAS-G、BASDAI、BASRI、BASMI和中醫(yī)證候評分,改善ESR、CRP、PHI和C_3水平且安全有效。
[Abstract]:Objective: to observe the efficacy and safety of acupuncture combined with Wuling decoction in the treatment of ankylosing spondylitis. Methods: 108 patients with ankylosing spondylitis were randomly divided into western medicine group. There were 36 cases in the traditional Chinese medicine group and 36 cases in the acupuncture and medicine group. The western medicine group was given sulfasalopyridine tablet, the traditional Chinese medicine group was treated with Wuling decoction, and the acupuncture and medicine group was treated with acupuncture combined with Wuling decoction for 60 days. The index of summation before and after treatment, the index of activity and the index of radiology before and after treatment were observed. The activity index of basic) and the scores of TCM syndrome differentiation ankylosing spondylitis (TCM syndrome) were measured before and after treatment with ESR C- reactive protein (CRP). The changes of parathyroid hormone (PHIH) and complement 3 (C3) were compared to compare the clinical efficacy and incidence of adverse reactions. Results: the total effective rate of acupuncture and medicine group was 71.4% after treatment. It was better than the western medicine group (58.1%) and the traditional Chinese medicine group (52.8%). The scores of the acupuncture and medicine group were better than that of the western medicine group and the traditional Chinese medicine group. Conclusion: acupuncture combined with Wuling decoction can significantly improve basic basic basic RI in patients with ankylosing spondylitis. BASMI and TCM syndromes score improved the level of BASMI CRP PHI and C _ (3), and were safe and effective.
【作者單位】： 河南中醫(yī)藥大學針推學院;河南中醫(yī)藥大學第三附屬醫(yī)院針灸科;
【基金】：河南省中醫(yī)藥大學博士科研基金項目(BSJJ2014-21)
【分類號】：R246.1
【正文快照】： 強直性脊柱炎(ankylosing spondylitis,AS)為一種侵害骶髂關(guān)節(jié)、外周關(guān)節(jié)、脊柱及脊柱旁軟組織的進行性炎癥疾病[1],其多發(fā)于20~35歲男性,為常見的風濕病之一,在我國發(fā)病率為0.25%~0.36%[2]。發(fā)病初期主要臨床表現(xiàn)為腰、背、頸、臀、髖部腫痛和活動受限。若未采取有效的治療措

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