本文關(guān)鍵詞：溫潛法治療慢性失眠虛陽上擾證臨床療效觀察　出處：《山東中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 慢性失眠 溫潛法 虛陽上擾證 臨床療效

【摘要】：目的:運(yùn)用溫潛法,以潛陽安神湯加減聯(lián)合佐匹克隆治療慢性失眠虛陽上擾證患者,多方面觀察其臨床療效,并進(jìn)行理論探討,為中醫(yī)藥治療失眠提供新思路及方法。方法:采取隨機(jī)化分組的原則,將入選的70例患者,隨機(jī)分為中藥聯(lián)合佐匹克隆試驗(yàn)組和佐匹克隆對(duì)照組,兩組各35例。兩組療程均為4周。治療結(jié)束后判定臨床療效,并觀察匹茲堡睡眠質(zhì)量指數(shù)(Pittsburgh Sleep Quality Index,PSQI)、Flinders疲勞量表(Flinders Fatigue Scale,FFS)、抑郁自評(píng)量表(Self-Rating Depression Scale,SDS)、焦慮自評(píng)量表(Self-Rating Anxiety Scale,SAS)、蒙特利爾認(rèn)知評(píng)估量表(Montreal Cognitive Assessment,MoCA)、虛陽上擾證癥狀分級(jí)量表的評(píng)分變化情況,隨時(shí)記錄治療過程中出現(xiàn)的不良反應(yīng)情況。結(jié)果:因部分患者依從性差而導(dǎo)致5例病例脫落,最終分析病例為65例,試驗(yàn)組33例,對(duì)照組32例。治療后,兩組療效經(jīng)等級(jí)秩和檢驗(yàn),P=0.0360.05,試驗(yàn)組總有效率為93.9%,對(duì)照組為75%,試驗(yàn)組有效率高于對(duì)照組。試驗(yàn)組在降低匹茲堡睡眠質(zhì)量指數(shù)、Flinders疲勞量表、抑郁自評(píng)量表、焦慮自評(píng)量表、虛陽上擾證癥狀分級(jí)量表評(píng)分方面均優(yōu)于對(duì)照組(P0.05或0.01)。兩組在提高蒙特利爾認(rèn)知評(píng)估量表評(píng)分方面未有明顯差異。試驗(yàn)組未發(fā)生明顯不良反應(yīng)。結(jié)論:以陽虛失眠為理論基礎(chǔ),溫潛法為基本治法,運(yùn)用潛陽安神湯加減聯(lián)合佐匹克隆治療慢性失眠虛陽上擾證具有較好的臨床療效,有利于患者提高睡眠效率、減輕日間疲勞及焦慮、抑郁情緒,改善腰膝酸軟、神疲倦怠、煩躁、心悸心慌、多汗、浮腫、耳鳴、大便稀癥狀,且無明顯不良反應(yīng),使患者的生存質(zhì)量得以提高。
[Abstract]:Objective: to observe the clinical effect of QYANS combined with Zopicron in the treatment of chronic insomnia with deficiency of yang and disturbance of yang in many aspects, and to explore its theory. Methods: 70 patients were randomly divided into Chinese medicine combined with zopicron test group and zopicron control group. There were 35 cases in each group. The course of treatment in both groups was 4 weeks. The Pittsburgh Sleep Quality Index (PSQI) was also observed. Flinders fatigue scale (FFSs). Self-Rating Depression scale (SDSs). Self-Rating Anxiety scale (SAS). The scores of Montreal Cognitive Assessment scale (Montreal Cognitive Assessment scale) and the symptom scale of deficiency and Yang disturbance (DYS) were evaluated by Montreal Cognitive Assessment scale (MCAA). Results: 5 cases fell off due to the poor compliance of some patients, 65 cases were analyzed, 33 cases in the test group and 32 cases in the control group. After rank sum test, the total effective rate of the two groups was 93.9 and that of the control group was 75%. The effective rate of the trial group was higher than that of the control group. The experimental group was reducing Pittsburgh Sleep quality Index Flinders fatigue scale, Self-Rating Depression scale, and Self-Rating anxiety scale. The score of the symptom scale of deficiency yang upper disturbance syndrome was better than that of the control group (P0.05 or 0.01). There was no significant difference between the two groups in improving the score of Montreal Cognitive Assessment scale. There was no significant adverse reaction in the test group. Conclusion: the theory is based on yang deficiency insomnia. Wenqian method is the basic treatment, using Qianyang Anshen decoction combined with Zopicron to treat chronic insomnia deficiency and yang disturbance syndrome has a good clinical effect, is conducive to improve the sleeping efficiency of patients, reduce daytime fatigue and anxiety. Depression mood, improving waist and knee weakness, fatigue, irritability, palpitation, sweating, swelling, tinnitus, stool, and no obvious adverse reaction, so that the patient's quality of life can be improved.
【學(xué)位授予單位】：山東中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R256.23

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本文編號(hào)：1435822