本文關(guān)鍵詞：電針與手針刺激對圍絕經(jīng)期烘熱癥狀及性激素水平影響的對比分析　出處：《湖南中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 手針 電針 圍絕經(jīng)期綜合征 烘熱 血清性激素水平

【摘要】：目的:本研究以圍絕經(jīng)期綜合征患者為觀察對象,分別以手針刺激與電針刺激作為治療手段,評價手針刺激和電針刺激對圍絕經(jīng)期綜合征烘熱及相關(guān)癥狀的療效對比;同時比較手針刺激和電針刺激對圍絕經(jīng)期綜合征患者性激素水平的影響,為針灸刺治療圍絕經(jīng)期綜合征的研究提供一定的臨床證據(jù)。方法:將50例圍絕經(jīng)期綜合征患者隨機分為手針組和電針組,脫落1例,有效病例49例,手針組27例,電針組22例。兩組均采用疏密波,頻率為10/50Hz,刺激30分鐘。兩組治療均隔日一次,每周3次,連續(xù)8周,共治療24次。研究于入組時、入組后第4、8、20、32周分別記錄患者的烘熱積分、絕經(jīng)癥狀評價量表評分(MRS)、圍絕經(jīng)期生活質(zhì)量量表評分(MENQOL),于入組時、入組后第8、20周檢查患者的血清性激素水平(FSH、LH、E2),并對數(shù)據(jù)進行統(tǒng)計與分析。結(jié)果:1.烘熱積分、MRS、MENQOL評分:與治療前比:兩組治療4周、8周及20周、32周隨訪,三者評分均有減少,差異有統(tǒng)計學(xué)意義(p0.05),說明兩組治療均能改善圍絕經(jīng)期患者烘熱及相關(guān)癥狀。與治療4周比:治療8周三者評分仍有降低,差異有統(tǒng)計學(xué)意義(p0.05),說明隨著治療周期的延長,患者烘熱及相關(guān)癥狀進一步改善。與治療8周時比:20周、32周的隨訪三者療效比較差異有統(tǒng)計學(xué)意義(p0.05),且與第20周隨訪時比:第32周隨訪MENQOL評分比較差異有統(tǒng)計學(xué)意義(p0.05),說明兩組在隨訪期隨著時間的推移,仍能進一步改善患者的烘熱及相關(guān)癥狀。2.血清性激素水平:與治療前比,兩組內(nèi)各時間點LH值稍有降低,但差異無統(tǒng)計學(xué)意義(p0.05);兩組治療8周及第20周隨訪較治療前FSH水平均有降低,差異有統(tǒng)計學(xué)意義(p0.05),但與治療第8周時比,第20周隨訪FSH值雖有降低,但差異無統(tǒng)計學(xué)意義(p0.05);兩組治療8周及第20周隨訪較治療前E2值有所提高,差異有統(tǒng)計學(xué)意義(p0.05),但與治療第8周時比,入組后20周隨訪E2值雖有升高,但差異無統(tǒng)計學(xué)意義(p0.05)。說明兩組治療均未能顯著影響患者的LH水平,但治療8周已有效調(diào)節(jié)患者FSH及E2水平,并維持到入組后20周。3.兩組間烘熱積分、MRS、MENQOL評分、血清FSH、LH、E2值比差異均無統(tǒng)計學(xué)意義(p0.05),該結(jié)果有待擴大樣本含量進一步驗證。結(jié)論:1.手針與電針對圍絕經(jīng)期烘熱及相關(guān)癥狀均有改善作用,且有較好的遠期療效。2.手針、電針對圍絕經(jīng)期綜合征患者血清性激素均有一定的調(diào)節(jié)作用。3.手針、電針對圍絕經(jīng)期綜合征療效無明顯差別,該結(jié)論有待進一步研究。
[Abstract]:Objective: to observe the patients with peri-menopausal syndrome and treat them with hand acupuncture and electroacupuncture respectively. To evaluate the efficacy of hand acupuncture stimulation and electroacupuncture stimulation in the treatment of peri-menopausal syndrome fever and related symptoms. At the same time, the effects of hand acupuncture stimulation and electroacupuncture stimulation on the sex hormone levels in patients with peri-menopausal syndrome were compared. Methods: 50 patients with peri-menopausal syndrome were randomly divided into hand acupuncture group and electroacupuncture group. 27 cases in the hand acupuncture group and 22 cases in the electroacupuncture group. The two groups were treated with 10 / 50 Hz stimulation for 30 minutes. The two groups were treated once every other day, 3 times a week for 8 weeks. A total of 24 times were treated. At the time of entering the group, the dry heat score and the menopausal symptom evaluation scale (MRS) were recorded respectively at the 4th week, 20th week, 20th week after entering the group. The quality of life scale (QOL) in the menopausal period was evaluated by MENQOLA, and the serum sex hormone level of the patients was examined at 8th week after entering the group and FSHLHHU E2). The data were analyzed and statistically analyzed. Results: the score of roasting heat score and MRSMENQOL score: compared with before treatment: the two groups were followed up for 4 weeks, 8 weeks and 20 weeks and 32 weeks, respectively. The scores of the three groups were all decreased. The difference was statistically significant (P 0.05), which indicated that both groups could improve the drying fever and related symptoms of perimenopausal patients. The difference was statistically significant (P 0.05), indicating that the baking heat and related symptoms improved further with the prolongation of the treatment cycle, compared with that at 8 weeks after treatment for 20 weeks. The results of 32 weeks follow-up showed significant difference among the three groups (p 0.05). And compared with the 20th week follow-up: the 32 week follow-up MENQOL score difference was statistically significant, indicating that the two groups in the follow-up period with the passage of time. The level of serum sex hormone: compared with before treatment, the LH value of the two groups decreased slightly at each time point, but the difference was not statistically significant (P 0.05). The FSH level of the two groups was significantly lower than that of the control group at 8 and 20 weeks, the difference was statistically significant (p 0.05), but compared with that at the 8th week, the FSH value of the follow-up at the 20th week was lower than that of the control group. But the difference was not statistically significant (P 0.05). The E _ 2 values of the two groups at 8 and 20 weeks were higher than those before treatment, and the difference was statistically significant (p 0.05). However, compared with the 8th week of treatment, the E _ 2 values of the 20 weeks follow up were higher than those of the control group. However, the difference was not statistically significant (P 0.05). It showed that the two groups of treatment did not significantly affect the level of LH, but after 8 weeks of treatment, the levels of FSH and E2 were effectively regulated. The results showed that there was no significant difference between the two groups in the score of roasting heat and the score of MRSMA MENQOL and the ratio of serum FSHN LHN E 2 between the two groups (P 0.05). The results need to be further verified by expanding the sample size. Conclusion 1. Both hand acupuncture and electroacupuncture can improve peri menopausal fever and related symptoms, and have a good long-term effect. 2. Hand acupuncture. Electroacupuncture has certain regulating effect on serum sex hormone in patients with perimenopausal syndrome .3.The curative effect of hand acupuncture and electroacupuncture on perimenopausal syndrome has no significant difference. This conclusion needs further study.
【學(xué)位授予單位】：湖南中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R246.3

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