本文關(guān)鍵詞：督脈經(jīng)埋線治療胃食管反流病的臨床研究　出處：《南京中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

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【摘要】：目的:通過(guò)客觀對(duì)比分析治療前后胃食管反流病癥狀改善情況,評(píng)價(jià)督脈經(jīng)埋線療法對(duì)胃食管反流病的有效性。通過(guò)臨床研究,進(jìn)一步探討埋線法治療胃食管反流病的技術(shù)操作方法,為形成可推廣應(yīng)用的方法提供依據(jù)。方法:將符合研究標(biāo)準(zhǔn)的50例胃食管反流病患者隨機(jī)分成治療組與對(duì)照組各25例。治療組予以督脈經(jīng)埋線治療,對(duì)照組服用由江蘇濟(jì)川制藥有限公司生產(chǎn)的雷貝拉唑腸溶膠囊。以六周為一個(gè)療程,觀察一個(gè)療程后兩組患者的癥狀改善情況。以RDQ、胃食管反流病生活質(zhì)量自評(píng)量表、SAS、SDS、GERDQ量表為評(píng)價(jià)指標(biāo),進(jìn)行治療前與治療后、組間與組內(nèi)臨床療效的比較。結(jié)果:1.治療組患者顯效13例,有效9例,無(wú)效3例;對(duì)照組顯效6例,有效10例,無(wú)效9例;治療組總有效率達(dá)88%,對(duì)照組總有效率為64%,差異具有統(tǒng)計(jì)學(xué)意義(P0.05);治療組顯效率為52%,對(duì)照組顯效率為24%,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。說(shuō)明治療組療效優(yōu)于對(duì)照組,且對(duì)于患者癥狀改善程度更為明顯。2.治療組治療后RDQ評(píng)分與治療前對(duì)比,差異具有統(tǒng)計(jì)學(xué)意義(P0.05),說(shuō)明督脈經(jīng)埋線療法對(duì)GERD治療有效;對(duì)照組治療后RDQ評(píng)分與治療前對(duì)比,差異具有統(tǒng)計(jì)學(xué)意義(P0.05),說(shuō)明口服雷貝拉唑?qū)ERD治療有效。3.治療后兩組RDQ、SAS、SDS、GERD-HRQL量表評(píng)分均顯著降低(P0.05),治療組治療后量表評(píng)分明顯低于對(duì)照組(P0.05),說(shuō)明督脈經(jīng)埋線療法與口服雷貝拉唑相比,更能改善GERD患者的癥狀、體征和焦慮、抑郁狀態(tài)以及生活質(zhì)量的影響。結(jié)論:督脈經(jīng)埋線治療胃食管反流病療效確切,優(yōu)于西藥治療組。督脈經(jīng)埋線能調(diào)整督脈氣機(jī)升降,不僅對(duì)GERD患者的反酸、燒心、非心源性胸痛、反食等臨床癥狀有很好的療效,而且對(duì)于患者的焦慮,抑郁狀態(tài)以及生活質(zhì)量也有明顯的改善。值得在臨床上作為一項(xiàng)治療GERD的新技術(shù)推廣和應(yīng)用。
[Abstract]:Objective: to analyze the improvement of gastroesophageal reflux disease (GERD) symptoms before and after treatment, and to evaluate the effectiveness of du meridian catgut embedding therapy for gastroesophageal reflux disease (GERD). To further explore the technique of embedding thread in the treatment of gastroesophageal reflux disease (GERD). Methods: 50 patients with gastroesophageal reflux disease were randomly divided into treatment group (n = 25) and control group (n = 25). The control group was treated with Rabeprazole enteric-coated capsule produced by Jiangsu Jichuan Pharmaceutical Co., Ltd. Six weeks as a course of treatment were used to observe the improvement of symptoms in the two groups after a course of treatment. RDQ was used. The quality of life (QOL) of gastroesophageal reflux disease (GERDQ) was evaluated by SASS-SDS+ GERDQ before and after treatment. Results 1. In the treatment group, there were 13 cases of remarkable effect, 9 cases of effective and 3 cases of failure. In the control group, 6 cases were effective, 10 cases were effective and 9 cases were ineffective. The total effective rate in the treatment group was 888.The total effective rate in the control group was 64. The difference was statistically significant (P 0.05). The effective rate of treatment group was 52 and that of control group was 24. The difference was statistically significant (P 0.05). The result showed that the effect of treatment group was better than that of control group. Treatment group after treatment RDQ score compared with before treatment, the difference was statistically significant (P0.05). The results showed that du meridian catgut embedding therapy was effective in the treatment of GERD. The RDQ scores of the control group after treatment were significantly different from those before treatment (P 0.05), indicating that oral rabeprazole was effective in the treatment of GERD. 3. After treatment, the two groups were treated with GERD. The scores of GERD-HRQL in the treatment group were significantly lower than those in the control group (P 0.05). Compared with oral rabeprazole, du meridian catgut embedding therapy can improve the symptoms, signs and anxiety of patients with GERD. Conclusion: the effect of embedding thread on gastroesophageal reflux disease is more effective than that of western medicine group. Not only for GERD patients with acid, heartburn, non-cardiogenic chest pain, anti-eating and other clinical symptoms have a good effect, but also for patients with anxiety. Depression and quality of life are also significantly improved, which is worthy of clinical application as a new technique for the treatment of GERD.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R246.1

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