本文關(guān)鍵詞：代謝綜合征女性人群體質(zhì)類型及相關(guān)因素分析　出處：《黑龍江中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 代謝綜合征 中醫(yī)體質(zhì) 女性人群

【摘要】：目的:代謝綜合征(Metabolic Syndrome,MS)是一種復(fù)雜的代謝紊亂綜合征,是心血管疾病和糖尿病的重要危險因素,和女性代謝性疾病如多囊卵巢綜合征(PCOS)、子宮內(nèi)膜癌、乳腺癌等的發(fā)生有密切相關(guān)性。本次研究選擇代謝綜合征女性患者人群,采用《中醫(yī)體質(zhì)分類與判定表》判定體質(zhì)類型和生化指標(biāo)檢測,觀察女性MS的主要體質(zhì)分布特點,分析MS與年齡的相關(guān)性,血壓與體重指數(shù)(body mass index,BMI)、空腹血糖(fasting blood-glucose,FPG)、甘油三酯(triglyceride,TG)、高密度脂蛋白-膽固醇(highdensity lipoprotein-cholesterol,HDL-C)的關(guān)系,總結(jié)中醫(yī)體質(zhì)和MS的相關(guān)性,以期通過調(diào)理體質(zhì)來改善MS的臨床癥狀,延緩疾病的發(fā)展進(jìn)程,并進(jìn)一步為防止相關(guān)婦科疾病的發(fā)生提供新的思路和方法。方法:選擇2015年06月-2016年12月就診于黑龍江中醫(yī)藥大學(xué)附屬第一醫(yī)院治未病中心科室的女性患者1000例,按照國際糖尿病聯(lián)盟2005年發(fā)布的MS全球共識納入篩選,對患者進(jìn)行血脂、空腹血糖、血壓、BMI、腹圍等相關(guān)指標(biāo)的測量,符合納入標(biāo)準(zhǔn)的為觀察組共297例,不符合的健康人群為對照組共248例。體質(zhì)量調(diào)查由專業(yè)人員指導(dǎo)患者填寫《中醫(yī)體質(zhì)辨識量表》,之后數(shù)據(jù)錄入數(shù)據(jù)庫,用SPSS22.0系統(tǒng)對數(shù)據(jù)進(jìn)行統(tǒng)計分析,得出結(jié)論。結(jié)果:1、觀察組中醫(yī)體質(zhì)分布比例:痰濕質(zhì)72例(24.24%)氣虛質(zhì)48例(16.16%)陽虛質(zhì)45例(15.15%)氣郁質(zhì)42例(14.14%)陰虛質(zhì)24例(8.08%)=血瘀質(zhì) 24 例(8.08%)濕熱質(zhì) 21 例(7.0 07%)特稟質(zhì) 12 例(4.04%)平和質(zhì)9例(3.03%);對照組中醫(yī)體質(zhì)分布比例:陽虛質(zhì)45例(18.15%)氣郁質(zhì)33例(13.31%)陰虛質(zhì)30例(12.10%)痰濕質(zhì)28例(11.29%)平和質(zhì)27例(10.89%)血瘀質(zhì)25例(10.08%)濕熱質(zhì)24例(9.68%)氣虛質(zhì)22例(8.87%)特稟質(zhì)14例(5.65%)。觀察組與對照組體質(zhì)類型分布上具有顯著性差異(P0.05)。2、MS女性患者年齡和體質(zhì)分布上無明顯統(tǒng)計學(xué)差異(P0.05)。3、以血壓分層研究,與正常組比較,高血壓組BMI、FPG和TG水平均偏高,HDL-C水平偏低,差異具有統(tǒng)計學(xué)意義(P0.05)。4、痰濕質(zhì)和氣虛質(zhì)最終進(jìn)入回歸方程中,相對危險度分別為EXP=3.000,EXP=2.545(P0.05)。結(jié)論:1、MS女性人群以痰濕質(zhì)為主,其次為氣虛質(zhì)、陽虛質(zhì)、氣郁質(zhì)、陰虛質(zhì)和血瘀質(zhì)、濕熱質(zhì)、特稟質(zhì)、平和質(zhì);MS與非MS女性人群在體質(zhì)分布上有顯著差異。2、MS女性人群年齡和9種體質(zhì)類型分布無明顯關(guān)系。3、MS女性人群中高血壓患者與血壓正常人群相比,肥胖和糖脂代謝紊亂更加嚴(yán)重,高血壓患者患MS的風(fēng)險較大。4、痰濕質(zhì)和氣虛質(zhì)對MS的發(fā)病有影響,可能是MS的危險體質(zhì)。
[Abstract]:Objective: metabolic syndromes (MS) is a complex metabolic disorder syndrome and an important risk factor for cardiovascular disease and diabetes mellitus. And female metabolic diseases such as polycystic ovary syndrome (PCOS), endometrial carcinoma, breast cancer and so on are closely related. This study selected female patients with metabolic syndrome. The classification and judgement table of TCM constitution was used to determine the physique type and biochemical index, to observe the main physique distribution characteristics of female MS, and to analyze the correlation between MS and age. Blood pressure and body mass index (BMIG), fasting blood glucose and glucose (FPG). Triglyceride triglyceride (TGN), high density lipoprotein cholesterol (HDL-C) lipoprotein-cholesterol. The correlation between TCM constitution and MS is summarized in order to improve the clinical symptoms of MS and delay the development of the disease by regulating the physique. It also provides new ideas and methods for preventing the occurrence of gynecological diseases. From June 2015 to December 2016, 1 000 female patients were selected from the department of the Center for treatment and Prevention in the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine. According to the MS global consensus released by the International Diabetes Federation in 2005, the patients were selected to measure blood lipids, fasting blood glucose, blood pressure BMIs, abdominal circumference and so on. 297 cases in the observation group and 248 cases in the control group were in accordance with the inclusion criteria. The investigation of body mass was conducted by the professionals to complete the TCM physique Identification scale. After that, the data is entered into the database, and the data is statistically analyzed with SPSS22.0 system, and the conclusion is drawn. The result is: 1. The distribution ratio of TCM constitution in observation group was: phlegm dampness in 72 cases, Qi deficiency in 48 cases, Yang deficiency in 45 cases, Qi stagnation in 42 cases, and Qi stagnation in 42 cases, respectively. There were 24 cases of yin deficiency and 24 cases of blood stasis, 24 cases of blood stasis, 21 cases of dampness and heat, 21 cases of dampness and heat, 7.07% of nature, 12 cases of nature, 4.04%) and 9 cases of mild quality (. 3.03; In the control group, the distribution ratio of TCM constitution was: Yang deficiency in 45 cases, Yang deficiency in 45 cases, Qi stagnation in 33 cases, Yin deficiency in 30 cases, phlegm dampness in 28 cases, and phlegm dampness in 28 cases. Calming 27 cases (10.89) blood stasis 25 cases (10.08) dampness and heat in 24 cases (9.68) Qi deficiency 22 cases (8.87)) the intrinsic quality is 14 cases (5.65%). There was significant difference in the distribution of physique type between the observation group and the control group (P 0.05). There was no significant difference in age and physique distribution in female patients with MS (P0.05. 3). Compared with normal group, BMIFPG and TG levels in hypertension group were higher than those in normal group. The level of HDL-C was low, the difference was statistically significant (P0.05. 4). Phlegm and dampness and deficiency of qi eventually entered the regression equation, and the relative risk was EXP=3.000. Conclusion the female population of MS was composed of phlegm and dampness, followed by qi deficiency, yang deficiency, qi stagnation, yin deficiency and blood stasis, dampness and heat, special nature and calmness. There was significant difference in physical distribution between MS and non-MS female population. 2. There was no significant relationship between age and distribution of 9 physique types in MS female population. Compared with normal blood pressure, obesity and disorder of glucose and lipid metabolism were more serious in female patients with MS. The risk of MS was higher in hypertensive patients. Phlegm dampness and deficiency of qi had influence on the incidence of MS. May be the dangerous constitution of MS.
【學(xué)位授予單位】：黑龍江中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R259

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