本文關(guān)鍵詞：子宮內(nèi)膜異位癥各期血瘀特點研究　出處：《福建中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 子宮內(nèi)膜異位癥/ASRM CA125抗原/血清、腹腔液 血瘀積分/分級

【摘要】：目的旨在了解子宮內(nèi)膜異位癥(Endometriosis, EMT)各期的血瘀積分及分級的差異性,并分析不同血瘀積分及分級的EMT患者血清及腹腔液糖類抗原125(CA125)表達(dá)差異,以期進(jìn)一步了解EMT各期的血瘀特點,為臨床上更好地中西醫(yī)結(jié)合防治EMT提供客觀理論依據(jù)。方法1.臨床研究：中醫(yī)采用證素辨證及證素積分的方法,對就診我院婦科住院部可疑子宮內(nèi)膜異位癥患者,進(jìn)行問卷調(diào)查,計算其血瘀積分及分級,研究EMT各期血瘀特點。2.實驗研究：收集經(jīng)腹腔鏡確診為子宮內(nèi)膜異位癥患者靜脈血3mL,并在手術(shù)進(jìn)腹后即取腹腔液2-5mL,位置為子宮膀胱反折腹膜處和子宮直腸陷凹處,血及腹腔液標(biāo)本均3000r/min離心l0min后取上清液,置-20℃冰箱內(nèi)保存待測,分析不同血瘀積分及分級的EMT患者血清、腹腔液CA125表達(dá)差異。結(jié)果1.子宮內(nèi)膜異位癥患者血瘀積分差異性比較：Ⅰ期與Ⅲ期、Ⅳ期,Ⅱ期與Ⅲ期、Ⅳ期的子宮內(nèi)膜異位癥患者血瘀積分對比具有差異性(P0.05)；Ⅰ期與Ⅱ期、Ⅲ期與Ⅳ期的子宮內(nèi)膜異位癥患者血瘀積分對比無差異性(P0.05)。2.子宮內(nèi)膜異位癥患者血瘀分級比較：Ⅰ期與Ⅲ期、Ⅳ期,Ⅱ期與Ⅲ期、Ⅳ期的子宮內(nèi)膜異位癥患者血瘀分級對比具有差異性(P0.05)；Ⅰ期與Ⅱ期、Ⅲ期與Ⅳ期的子宮內(nèi)膜異位癥患者血瘀分級對比無差異性(P0.05)。3.子宮內(nèi)膜異位癥患者血清CA125、腹腔液CA125與血瘀積分進(jìn)行相關(guān)性分析,結(jié)果顯示兩者具有正相關(guān)關(guān)系,相關(guān)系數(shù)分別為0.378、0.434(P0.05)。結(jié)論1.根據(jù)國際ASRM評分標(biāo)準(zhǔn),將"f15劃分為輕型子宮內(nèi)膜異位癥,15劃分為中重型子宮內(nèi)膜異位癥,則輕型子宮內(nèi)膜異位癥患者(Ⅰ期與Ⅱ期)或者中重型子宮內(nèi)膜異位癥患者(Ⅲ期與Ⅳ期)血瘀病變的程度沒有差異性；而中重型子宮內(nèi)膜異位癥患者的血瘀病變程度則高于輕型子宮內(nèi)膜異位癥患者。2.子宮內(nèi)膜異位癥患者血清CA125、腹腔液CA125與血瘀積分具有相關(guān)關(guān)系。
[Abstract]:Objective to investigate the difference of blood stasis score and grade of Endometriosissis (EMT) in different stages of endometriosis. The differences of serum and peritoneal fluid carbohydrate antigen 125 CA125 in patients with EMT with different blood stasis scores and grades were analyzed in order to further understand the characteristics of blood stasis in different stages of EMT. In order to provide an objective theoretical basis for the better integration of traditional Chinese and western medicine in the prevention and treatment of EMT methods: 1. Clinical study: syndrome differentiation and syndromes integral method is used in TCM. 2. The patients with suspected endometriosis in gynecological hospital were investigated by questionnaire and their blood stasis scores and grades were calculated. To study the characteristics of blood stasis in different stages of EMT. 2. Experimental study: collect 3 mL venous blood from patients with endometriosis diagnosed by laparoscope, and then take 2 to 5 mL peritoneal fluid after operation. The location was at the retrograde peritoneum of the uterus and bladder and the rectum of the uterus and rectum. The blood and peritoneal fluid samples were centrifuged for 10 minutes, then the supernatant was collected and stored in the refrigerator at -20 鈩，

本文編號：1384537