本文關(guān)鍵詞：不換金正氣散加減方治療腹瀉型腸易激綜合征寒濕蘊(yùn)脾證的療效對(duì)比研究　出處：《南京中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 腹瀉型腸易激綜合征 不換金正氣散 柔肝緩急 祛風(fēng)除濕

【摘要】：目的:觀察不換金正氣散分別配伍柔肝緩急藥及祛風(fēng)除濕藥治療腹瀉型腸易激綜合征寒濕蘊(yùn)脾證的臨床療效,探討不同配伍的中藥對(duì)IBS-D寒濕蘊(yùn)脾證的療效特點(diǎn),由此探討腹瀉型腸易激綜合征寒濕蘊(yùn)脾證的辨證要點(diǎn)及其用藥特點(diǎn),為中醫(yī)臨床治療IBS-D寒濕蘊(yùn)脾證提供新的思路。研究方法:受試對(duì)象均是2015年03月至2017年2月期間在江蘇省中醫(yī)院消化內(nèi)科就診的患者,總共90人。所有病例均符合羅馬Ⅲ診斷標(biāo)準(zhǔn),中醫(yī)辨證為寒濕蘊(yùn)脾證。隨機(jī)分為治療組1、治療組2和對(duì)照組各30例。治療組1給予不換金正氣散配伍柔肝緩急藥,治療組2給予不換金正氣散配伍祛風(fēng)除濕藥,對(duì)照組給予雙歧桿菌三聯(lián)活菌膠囊(培菲康),療程為4周,記錄治療前、治療后的癥狀評(píng)分。結(jié)果:1.總體臨床療效:治療組1總有效率為93.33%;治療組2總有效率為90.0%;對(duì)照組總有效率為76.67%。經(jīng)統(tǒng)計(jì)學(xué)處理,治療組1與治療組2總有效率無明顯差異(P0.05),中藥治療組1和2療效均優(yōu)于西藥對(duì)照組(P值均0.0125)。2.臨床癥狀積分方面,治療前后三組癥狀總積分均有顯著統(tǒng)計(jì)學(xué)意義(P0.01)。治療組1與治療組2相比,兩組治療前后癥狀總積分減少無差異(P0.05),均優(yōu)于對(duì)照組(P0.05)。3.在改善腹痛或腹部不適、腹痛欲瀉、瀉后痛緩、情緒抑郁或煩躁方面,治療組1優(yōu)于對(duì)照組。治療組1與治療組2、治療組2與對(duì)照組相比均無統(tǒng)計(jì)學(xué)差異。但治療組1癥狀評(píng)分緩解程度大于治療組2。4.在改善大便性狀、受涼或飲食生冷后發(fā)作加重、畏寒怕冷癥狀方面,治療組1和治療組2無統(tǒng)計(jì)學(xué)差異,均優(yōu)于對(duì)照組。但治療組2癥狀評(píng)分緩解程度大于治療組1。5.在改善大便次數(shù)、腸鳴矢氣和食欲不振癥狀方面,三組均有較好的療效,無明顯差異。結(jié)論:不換金正氣散配伍柔肝緩急藥與祛風(fēng)除濕藥和培菲康均對(duì)IBS-D有明顯療效,且兩組中藥的療效優(yōu)于西藥,但兩中藥組間療效無統(tǒng)計(jì)學(xué)差異。配伍柔肝緩急藥能更好地改善患者腹痛或腹部不適、腹痛欲瀉、瀉后痛緩、情緒抑郁或煩躁的癥狀。配伍祛風(fēng)除濕藥能更好地改善患者大便性狀、受涼或飲食生冷后發(fā)作加重、畏寒怕冷癥狀。
[Abstract]:Objective: to observe the clinical curative effect of Fuchangjin Zhengqi powder combined with soften liver slow medicine and expelling wind and dehumidifying medicine on cold dampness and spleen syndrome of diarrhea type irritable bowel syndrome. Objective: to explore the therapeutic effects of different combinations of traditional Chinese medicine on IBS-D syndrome of cold and dampness and spleen retention, and to explore the main points of syndrome differentiation and the characteristics of drug use of the syndrome of diarrhea type irritable bowel syndrome. Methods: from March 2015 to February 2017, the subjects were all the patients in the Department of Gastroenterology of Jiangsu Provincial Hospital of traditional Chinese Medicine. A total of 90 people. All cases were in accordance with the Rome 鈪，

本文編號(hào)：1368453