本文關(guān)鍵詞：益肺灸對慢性阻塞性肺疾病生存質(zhì)量的影響　出處：《河南中醫(yī)藥大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

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【摘要】：目的:觀察慢性阻塞性肺疾病(COPD)穩(wěn)定期患者的CAT問卷、SF-36量表、患者臨床報告結(jié)局、療效滿意度和皮膚致敏評價等結(jié)局指標(biāo),評價益肺灸治療對COPD患者生存質(zhì)量的影響。方法:采取隨機(jī)對照的分組方法,將COPD穩(wěn)定期患者分為試驗組60例和對照組60例,試驗組在維持原有治療的基礎(chǔ)上配合益肺灸治療,對照組維持原有治療,治療3個月。以患者CAT問卷、SF-36量表、患者臨床報告結(jié)局、療效滿意度、皮膚致敏評價為結(jié)局指標(biāo)。采用SPSS20.0進(jìn)行統(tǒng)計分析。結(jié)果:共納入患者120例,脫落18例,有效患者共102例,其中試驗組50例,對照組52例。兩組基線無統(tǒng)計學(xué)差異,具有可比性。臨床觀察如下:1.CAT問卷治療前,兩組CAT評分無統(tǒng)計學(xué)意義(P0.05)。治療后,兩組間CAT評分比較有統(tǒng)計學(xué)差異(P0.05)。治療后,試驗組CAT評分下降較治療前顯著(P0.01),對照組CAT評分較治療前下降(P0.05)。2.SF-36量表治療前,兩組生理機(jī)能、一般健康、生理職能、精力、情感職能、社會功能、身體疼痛和精神健康得分均無統(tǒng)計學(xué)意義(P0.05)。治療后兩組間除精神健康和情感職能得分無統(tǒng)計學(xué)意義(P0.05)外,其余方面得分比較均有統(tǒng)計學(xué)差異(P0.05)。治療后,試驗組除精神健康和情感職能得分較治療前比較差異無統(tǒng)計學(xué)意義(P0.05)外,其余方面得分較治療前升高(P0.05),對照組除身體疼痛、精神健康和情感職能得分較治療前比較差異無統(tǒng)計學(xué)意義(P0.05)外,其余方面得分較治療前升高(P0.05)。3.COPD病人報告的臨床結(jié)局(COPD-PRO)治療前,兩組患者臨床癥狀評分、療效滿意度評分、健康滿意度評分和COPD-PRO總評分無統(tǒng)計學(xué)意義(P0.05)。治療后兩組間上述各領(lǐng)域評分比較有統(tǒng)計學(xué)意義(P0.05)。治療后,試驗組上述各領(lǐng)域評分較治療前下降顯著(P0.01),對照組除健康滿意度評分較治療前比較差異無統(tǒng)計學(xué)意義(P0.05)外,其余各領(lǐng)域評分較治療前下降(P0.05)。4.患者療效滿意度(ESQ-COPD)治療前,兩組臨床癥狀評分、治療效果評分、總體療效評分、工作生活能力評分和ESQ-COPD總評分無統(tǒng)計學(xué)差異(P0.05)。治療后兩組間上述領(lǐng)域評分比較均有統(tǒng)計學(xué)差異(P0.05)。治療后試驗組上述各領(lǐng)域評分較治療前比較升高顯著(P0.01),對照組除臨床癥狀評分評分較治療前比較差異均無統(tǒng)計學(xué)意義(P0.05),其余各領(lǐng)域評分較治療前比較升高(P0.05)。在治療方便評分方面,治療前后兩組間比較和兩組治療前后比較均無統(tǒng)計學(xué)意義(P0.05)。5.皮膚致敏評價治療期間兩組發(fā)生皮膚致敏反應(yīng)無統(tǒng)計學(xué)意義(P0.05)。試驗組在治療1個月期間有2例患者出現(xiàn)皮膚明顯紅斑,評分等于2分判定為致敏陽性;治療3個月期間有4例患者出現(xiàn)皮膚致敏陽性,1例表現(xiàn)為輕微紅斑伴輕微水腫,另3例表現(xiàn)為明顯紅斑。治療后試驗組共6例患者出現(xiàn)皮膚致敏陽性,致敏率為4%,致敏等級屬Ⅰ級,致敏強(qiáng)度弱。對照組未進(jìn)行益肺灸治療。結(jié)論:1益肺灸治療能改善COPD穩(wěn)定期患者臨床癥狀,改善日常工作生活和交往能力,使患者生存質(zhì)量得到一定改善。2益肺灸治療能提高患者的治療效果,對患者的療效滿意度具有一定的改善。3益肺灸治療皮膚致敏強(qiáng)度弱,發(fā)生皮膚致敏率低。
[Abstract]:Objective: To observe the effect of chronic obstructive pulmonary disease (COPD) patients with stable CAT questionnaire, SF-36 scale, patients reported outcomes, curative effect satisfaction and skin sensitization evaluation outcome indicators, impact on quality of life in patients with the treatment of COPD evaluation of Yifei moxibustion. Methods: according to the method of random grouping, the patients with COPD the stable period is divided into 60 cases of test group and 60 cases in the control group, experimental group with Yifei moxibustion therapy based on maintaining the original treatment, the control group was given conventional treatment, treatment for 3 months. The patients with CAT questionnaire, SF-36 scale, the satisfaction of patients with clinical outcome, report, skin sensitization evaluation outcome. SPSS20.0 was used for statistical analysis. Results: 120 patients were included, 18 cases of loss, effective with a total of 102 cases, 50 cases in test group, 52 cases in the control group. No significant difference between the two groups at baseline, comparable. Clinical observation as follows: 1.CAT questionnaire before treatment, The CAT scores of the two groups had no statistical significance (P0.05). After the treatment, CAT scores between the two groups was statistically significant (P0.05). After treatment, the test group CAT score decreased significantly compared with those before treatment (P0.01), the control group CAT score decreased (P0.05).2.SF-36 scale before treatment, two groups of physiological function, general health, physiological function, energy, emotional function, social function, physical pain and mental health scores were not statistically significant (P0.05). After treatment between the two groups in the scores of mental health and emotional function was not statistically significant (P0.05), the scores were statistically significant (P0.05). After the treatment, test in the group of mental health and emotional function score compared with before treatment there was no statistically significant difference (P0.05), the rest were higher than before treatment (P0.05), the control group in addition to physical pain, mental health and emotional function score compared with before treatment there was no significant difference Significance (P0.05), the rest were higher than before treatment (P0.05) clinical outcome in patients with.3.COPD report (COPD-PRO) before treatment, two groups of patients with clinical symptom score, curative effect satisfaction score, health satisfaction score and COPD-PRO total score was not statistically significant (P0.05). After treatment, scores of the two groups of the field there was statistical significance (P0.05). After treatment, the group test score decreased significantly (P0.01), the control group in addition to health satisfaction score than before treatment had no significant difference (P0.05) score, the rest of the field was decreased compared with that before treatment (P0.05) curative effect satisfaction in patients with.4. (ESQ-COPD) before treatment., two groups of clinical symptom score, curative effect score, overall efficacy score, no significant difference between the work life ability score and ESQ-COPD total score (P0.05). After treatment, scores of the two groups in these areas were statistically difference ISO (P0.05). After the treatment group test score in each of these areas is significantly higher than that before treatment (P0.01), the control group except the difference between clinical symptom score score before treatment were not statistically significant (P0.05) score, the rest of the field increased compared with before treatment (P0.05). In the treatment of convenient score, before and after treatment and the comparison between the two groups before and after treatment in the two groups were not statistically significant (P0.05) between the two groups had no statistically significant skin sensitization treatment induced skin sensitivity evaluation.5. (P0.05). The experimental group has 2 patients appeared obvious erythema in skin during 1 months of treatment, the score is equal to 2 for the determination of sensitization positive; during the 3 months of treatment 4 cases of patients with positive skin sensitization, 1 cases showed mild erythema and slight edema, the other 3 cases showed obvious erythema. Experimental group after treatment were 6 cases of patients with positive skin sensitization, allergic sensitization rate was 4%, grade genus Grade I, sensitized with weak intensity. The control group without Yifei moxibustion treatment. Conclusion: 1 Yifei moxibustion therapy can improve clinical symptoms of patients with stable COPD, improve the daily life and communication ability, the quality of life of patients with improved.2 Yifei moxibustion therapy can improve the curative effect, has certain improvement.3 Yifei moxibustion in the treatment of skin sensitization effect on the strength of weak patient satisfaction, the occurrence of skin sensitization rate is low.

【學(xué)位授予單位】：河南中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R246.1

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