本文關(guān)鍵詞：傷科黃水治療急性痛風(fēng)性關(guān)節(jié)炎的臨床研究　出處：《廣州中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 痛風(fēng)性關(guān)節(jié)炎 急性期 傷科黃水 臨床療效 安全性

【摘要】：目的:通過觀察經(jīng)傷科黃水外敷治療后急性痛風(fēng)性關(guān)節(jié)炎患者的血沉、C-反應(yīng)蛋白、血尿酸、VAS評(píng)分、臨床癥狀體征等指標(biāo)的變化,評(píng)估傷科黃水的臨床療效及安全性。方法:計(jì)算機(jī)軟件生成隨機(jī)數(shù)字,按入組順序隨機(jī)將確診為急性痛風(fēng)性關(guān)節(jié)炎患者90例分為治療組和對(duì)照組,每組各45例。對(duì)照組予秋水仙堿片(0.5mgP.Otid)治療;治療組在此基礎(chǔ)上,加用傷科黃水外敷病變關(guān)節(jié)處。每組療程均為1周。觀察兩組患者治療前后的ESR、CRP、UA、VAS評(píng)分、臨床癥狀積分、臨床療效、不良反應(yīng)等指標(biāo)的變化,客觀綜合評(píng)價(jià)外敷傷科黃水治療急性痛風(fēng)性關(guān)節(jié)炎的臨床療效、安全性。結(jié)果:①兩組間的基線指標(biāo)均無顯著性差異(P0.05)。②兩組患者的ESR、CRP、VAS評(píng)分在治療前無顯著差異(P0.05)。治療后,兩組患者的ESR、CRP、VAS評(píng)分較治療前均有顯著降低(P0.05),且治療組的降低程度較對(duì)照組更為明顯(P0.05)。③兩組患者的血尿酸水平在治療前無顯著差異(P0.05)。治療后,兩組患者血尿酸水平較治療前降低(P0.05),但治療組的血尿酸下降幅度較對(duì)照組無顯著性差異(P0.05)。④兩組治療前臨床癥狀積分比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05);兩組治療后的臨床癥狀積分較治療前均降低(P0.05);且治療組的治療后臨床癥狀積分明顯低于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。⑤治療后,治療組顯效15例(33.33%),有效27例(60%),無效3例(6.67%),總有效率93.33%。對(duì)照組顯效11例(13.33%),有效25例(66.67%),無效9例(20%),總有效率為80%。在臨床療效上治療組顯著優(yōu)于對(duì)照組(P0.05)。⑥治療后,兩組患者出現(xiàn)的不良反應(yīng)無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:①傷科傷科黃水能夠降低急性痛風(fēng)性關(guān)節(jié)炎患者的炎癥指標(biāo)、VAS評(píng)分、臨床癥狀積分。②傷科傷科黃水聯(lián)合西藥治療急性痛風(fēng)性關(guān)節(jié)炎患者較單純西藥具有明顯臨床療效。③傷科傷科黃水治療急性痛風(fēng)性關(guān)節(jié)炎安全有效,值得推廣,可成為一種有效的中醫(yī)治療方法。
[Abstract]:Objective: To observe the water treatment after ESR Department of Traumatology patients with acute gouty arthritis, C- reactive protein, uric acid, VAS score, changes of clinical symptoms and signs such as indicators of the evaluation of clinical efficacy and safety of Department of Traumatology water. Methods: computer software to generate random numbers, according to the group order were diagnosed as 90 cases of acute gouty arthritis patients were divided into treatment group and control group, 45 cases in each group. The control group was treated with Colchicine Tablets (0.5mgP.Otid) treatment; treatment group on the basis of this, combined with the Department of Traumatology and topical lesion joints. Each group was treated for 1 weeks. Observe two groups of patients before and after treatment of ESR, CRP, UA. VAS score, clinical symptom score, clinical efficacy, adverse reactions and other indicators of change, clinical efficacy, objective evaluation of external water department of Traumatology for treatment of acute gouty arthritis safety. Results: the baseline characteristics between the two groups were not significant 鎬у樊寮，

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