發(fā)布時間：2022-01-16 17:13

　　一氧化氮（NO）自由基是氣血通暢的動力之一;抗氧化劑清除氧自由基,保護(hù)NO并且能夠協(xié)助NO共同促進(jìn)氣血通暢,預(yù)防和保護(hù)心腦血管的健康;NO和天然抗氧化劑可以延緩衰老,還可以協(xié)同預(yù)防和治療炎癥引起的損傷;包含天然抗氧化劑的中草藥,促進(jìn)氣血通暢,溶化血栓,是中草藥通過一氧化氮自由基活血化瘀的機(jī)理. 

【文章來源】：生物化學(xué)與生物物理進(jìn)展. 2020,47(08)北大核心SCICSCD

【文章頁數(shù)】：14 頁

【文章目錄】：
1 Nitric oxide free radical is a driving force for free Qi-blood circulation
    1.1 NO is endothelium-derived relaxing factor(EDRF)
    1.2 Microcirculation is the basic for Qi-blood circulation and exchange of materials and energy
    1.2 Targeted delivery of nitric oxide via a"bump-and-hole"-based enzyme-prodrug pair
2 Natural antioxidants protect NO free radicals and exert the driving force of Qiblood patency
    2.1 Natural antioxidants protect NO to play the driving force of Qi and blood patency
    2.2 Regulatory effect of natural antioxidant ginkgo flavone on NO production during cardiac ischemia-reperfusion
    2.3 Promoting effect of natural antioxidant Chinonin on NO production during cardiac ischemia-reperfusion
    2.4 The effect of natural antioxidant Crataegus flavonoids on NO production in stroke
    2.5 Promotion of NO production by endothelial cells by natural antioxidant L-theanine
    2.6 Taking cocoa polyphenols decrease blood pressure and increases nitric oxide
3 Synergistic protective and promotive effectsof natural antioxidants and NO free radicalon cardiovascular and cerebrovascular health
    3.1 The formula has obvious scavenging effect on oxygen free radicals and decreasing the increases of blood lipid,blood sugar and blood pressure
    3.2 The formula has obvious inhibitory effect on pulmonary enlargement induced cell damage and rat heart ischemia damage by intraperitoneal injection of isoproterenol
    3.3 The formula has protective effect of NO on brain against ischemia-reperfusion damage
    3.4 The formula has significant protective effect on the paralysis behavior of nematodes in animals with Alzheimer's disease induced by A-beta
4 Natural antioxidants and nitric oxide can synergistically eliminate the damage caused by inflammation
5 Nitric oxide and natural antioxidants prolong the longevity of nematodes
    5.1 Bacterial nitric oxide extends the lifespan of C.elegans
    5.2 Natural antioxidants extends the lifespan of C.elegans
6 Traditional Chinese medicines including natural antioxidants ensure health by activating blood circulation and removing blood stasis
7 Conclusion


【參考文獻(xiàn)】：
期刊論文
[1]心氣虛血瘀的科學(xué)內(nèi)涵和芪參益氣滴丸補(bǔ)氣活血的作用機(jī)理[J]. 韓晶巖.  世界科學(xué)技術(shù)-中醫(yī)藥現(xiàn)代化. 2019(02)
[2]A lumbrokinase isozyme targets hepatitis B e-antigen[J]. Yuan Zhou,Xiumei Wang,Shichao Fan,Rongqiao He.  Science China（Life Sciences）. 2018(12)
[3]基于一氧化氮和天然抗氧化劑的新配方的心肌保護(hù)作用[J]. 馮潤,王紅云,趙保路,陸忠兵.  中國科學(xué)院大學(xué)學(xué)報. 2016(05)
[4]L-精氨酸和天然抗氧化劑對缺血性腦卒中防治作用的細(xì)胞和動物模型研究[J]. 趙亞碩,李硯超,杜立波,趙保路,劉揚,常彥忠.  心腦血管病防治. 2016(04)
[5]利用電子自旋共振（ESR）技術(shù)研究一氧化氮自由基在心腦血管疾病和健康中的“雙刃劍”作用（英文）[J]. 趙保路.  波譜學(xué)雜志. 2015(02)
[6]The cessation and detoxification effect of tea filters on cigarette smoke[J]. YAN JingQi1,2,DI XiaoJing1,4,LIU CaiYi3,ZHANG HuiMin3,HUANG XiouQin3,ZHANG JunJing1,2,ZHAO Yan5,ZHANG LongZe1,CHANG YanZhong4,LIANG YongLin2$,TAO Ran3 & ZHAO BaoLu1,21 State Key Laboratory of Brain and Cognitive Science,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China;2 Key Laboratory of Mental Health,Institute of Psychology,Chinese Academy of Sciences,Beijing 100101,China;3 Addiction Branch,Beijing Military Region General Hospital,Beijing 100700,China;4 Institute of Molecular Neurobiology,Hebei Normal University,Shijiazhuang 050016,China;5 Department of Food Sciences and Technology,Harbin Institute of Technology at Weihai,Weihai 264209,China.  Science China（Life Sciences）. 2010(05)
[7]Nitric oxide and oxygen radicals induced apoptosis via bcl-2 and p53 pathway in hypoxia-reoxygenated cardiomyocytes[J]. 沈劍剛,丘幸生,姜泊,張德良,忻文娟,趙保路.  Science in China（Series C:Life Sciences）. 2003(01)
[8]NO·自由基的性質(zhì)及其生理功能[J]. 趙保路,陳惟昌.  生物化學(xué)與生物物理進(jìn)展. 1993(06)



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