【摘要】：隨著軍事科技的發(fā)展和軍隊(duì)現(xiàn)代化建設(shè)的不斷加強(qiáng)，各國軍隊(duì)的遠(yuǎn)程打擊能力大大的得到提高，同其他常規(guī)武器相比，爆炸性武器具有更強(qiáng)的摧毀力和殺傷力，這就使得爆震傷在現(xiàn)代戰(zhàn)爭中所占的比重越來越大，爆震傷已經(jīng)成為戰(zhàn)爭中脊柱、脊髓損傷的主要原因。由于脊髓爆震傷與機(jī)械性的ASCI在發(fā)生機(jī)制上有所不同，那么它們傷后的病理改變及救治方法也就不同，目前有關(guān)這方面的內(nèi)容在國內(nèi)外研究的都比較少，而現(xiàn)存的相關(guān)理論和治療手段都已經(jīng)落后，不能滿足現(xiàn)代戰(zhàn)爭條件下脊髓爆震傷的要求，本課題的目的是研究脊柱、脊髓爆震傷后，脊髓前角運(yùn)動(dòng)神經(jīng)元的病理生理變化并初步觀察不同的治療方法對(duì)其自然轉(zhuǎn)歸的影響，為臨床有針對(duì)性的研究治療方案具有一定的價(jià)值，，為提高我軍戰(zhàn)斗力，降低傷殘率而服務(wù)。 一、爆震傷后脊髓前角運(yùn)動(dòng)神經(jīng)元病理形態(tài)學(xué)變化 研究對(duì)象和材料：健康家兔30只，雌雄不拘，爆炸源采用軍用單質(zhì)金屬炸藥黑索金(RDX)，將其制作成0.9g銅殼圓柱狀小型爆炸裝置。
[Abstract]:With the development of military science and technology and the continuous strengthening of the modernization of the armed forces, the long-range strike capability of the armed forces of various countries has been greatly improved, and compared with other conventional weapons, explosive weapons have a stronger destructive power and killing power. This makes detonation injury more and more important in modern war. Detonation injury has become the main cause of spinal and spinal cord injury in war. Because the mechanism of spinal cord knock injury is different from that of mechanical ASCI, then their pathological changes and treatment methods are different. At present, there is little research on this aspect at home and abroad. And the existing relevant theories and treatment methods have been backward, can not meet the requirements of the modern war conditions of the spinal cord explosive injury, the purpose of this subject is to study the spinal cord, after the spinal cord explosion injury, the purpose of this topic is to study the spinal cord, spinal cord explosive injury, The pathophysiological changes of motor neurons in the anterior horn of spinal cord were observed and the effects of different treatment methods on their natural outcome were observed. It is of certain value for the clinical research and treatment of motor neurons in the anterior horn of the spinal cord and to improve the combat effectiveness of our army. Reduce the disability rate and serve. 1. Pathomorphological changes of motoneurons in anterior horn of spinal cord after blast injury: thirty healthy rabbits, both male and female, were used in this study. The explosive source was (RDX), a simple metal explosive for military use. The device was made into a 0.9 g copper shell cylindrical small explosive device.
【學(xué)位授予單位】：第四軍醫(yī)大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2006
【分類號(hào)】：R82

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