【摘要】：目的　探討南方部隊(duì)結(jié)核病的分子流行病學(xué)規(guī)律。方法　設(shè)計(jì)一對(duì)特異性IS6 110外向性引物 ,應(yīng)用聚合酶鏈反應(yīng) (PCR)建立檢測結(jié)核分支桿菌DNA指紋多態(tài)性的方法 ,分析結(jié)核分支桿菌DNA多態(tài)性與流行病學(xué)的關(guān)系。結(jié)果　共檢測分析了 15 4株結(jié)核分支桿菌DNA的指紋多態(tài)性。根據(jù)這些菌株的指紋多態(tài)性特征共分為 8個(gè)類型 ,以Ⅰ型 (36 .4 % )、Ⅱ型 (31.8% )和Ⅲ型(2 1.4 % )為主 ,其余各型均少于 4 %。以 2 0～ 2 9歲和 30～ 39歲組在這三型中所占比例最大 ,分別為31.8%和 2 7.9%。駐城鎮(zhèn)部隊(duì)與駐鄉(xiāng)村部隊(duì)以及結(jié)核病患者有無卡介苗接種史 ,在這三型的
[Abstract]:Objective to investigate the molecular epidemiology of tuberculosis in southern army. Methods A pair of specific IS6 110 extroversion primers were designed to detect the DNA fingerprinting polymorphism of Mycobacterium tuberculosis by polymerase chain reaction (PCR). The relationship between DNA polymorphism and epidemiology of Mycobacterium tuberculosis was analyzed. Results the fingerprinting polymorphism of 154 strains of Mycobacterium tuberculosis DNA was analyzed. According to the fingerprinting polymorphism of these strains, they were divided into 8 types, mainly type 鈪，

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