【摘要】：目的調(diào)查分析海軍部隊(duì)高強(qiáng)度軍事訓(xùn)練后腎臟損傷的發(fā)生情況。方法受試對(duì)象為1 320名進(jìn)行5km武裝越野跑的海軍部隊(duì)官兵,其中新兵568人,老兵752人。訓(xùn)練完成后即刻留取尿液,以干化學(xué)法進(jìn)行蛋白尿及血紅蛋白檢測(cè);尿液離心后行紅細(xì)胞鏡檢;ELISA法檢測(cè)尿N-乙酰-β-D-氨基葡萄糖苷水解酶(NAG)和視黃醇結(jié)合蛋白(RBP)水平;以酶偶聯(lián)法測(cè)定血肌酸激酶(CK)水平,以CK≥950U/L作為橫紋肌溶解癥診斷標(biāo)準(zhǔn)。結(jié)果訓(xùn)練后總體血尿發(fā)生率為2.1%,血紅蛋白尿發(fā)生率為7.4%,蛋白尿陽(yáng)性率為44%,尿NAG異常率為57.1%,尿RBP異常率為57.3%,且新兵均高于老兵(P0.05);各檢測(cè)項(xiàng)目訓(xùn)練結(jié)束24h后80%左右的官兵上述指標(biāo)恢復(fù)正常,訓(xùn)練結(jié)束48h后90%左右恢復(fù)正常;以上指標(biāo)復(fù)合異常(即至少有一項(xiàng)異常)發(fā)生率為78.2%。橫紋肌溶解癥發(fā)生率為0.3%,無(wú)急性腎功能衰竭出現(xiàn)。結(jié)論海軍部隊(duì)高強(qiáng)度軍事訓(xùn)練后腎臟損傷發(fā)生率較高,且新、老兵之間存在明顯差異,極少數(shù)官兵可發(fā)生橫紋肌溶解癥。
[Abstract]:Objective to investigate and analyze the incidence of renal injury after high-intensity military training. Methods the subjects were 1 320 navy officers and soldiers who were involved in 5km armed cross-country running, including 568 recruits and 752 veterans. Urine was collected immediately after training, proteinuria and hemoglobin were detected by dry chemical method, erythrocyte microscopy was performed after urine centrifugation, urinary N- acetyl- 尾-D-glucosaminoside hydrolase (NAG) and retinol binding protein (RBP) were detected by ELISA method. The level of serum creatine kinase (CK) was measured by enzyme coupling method, and CK 鈮，

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