海水浸泡開放性犬顱腦爆震傷影像學(xué)變化及機(jī)制實(shí)驗(yàn)研究
本文選題:爆震傷 + 海水 ; 參考:《第四軍醫(yī)大學(xué)》2010年碩士論文
【摘要】: 目的:研究海戰(zhàn)條件下開放性顱腦爆震傷動物模型顱腦影像學(xué)的變化特點(diǎn)。 方法:以狗顱中線向左(右)1cm,眶上緣向上1cm交界處為爆炸中心位置。將15只犬根據(jù)爆炸距離(爆炸源最低點(diǎn)距爆炸點(diǎn)的距離)分為3組,分別為3mm組、3.5mm組、4mm組。比較各個(gè)組的爆炸效果,選出最適的爆炸距離為3.5mm。再將20只犬隨機(jī)分為對照組(非海水浸泡),實(shí)驗(yàn)組(海水浸泡)。以爆炸距離3.5mm致傷后,實(shí)驗(yàn)組犬受傷腦組織浸泡于海水環(huán)境中,比較兩組犬致傷3h、5h、8h后顱腦CT的動態(tài)變化。 結(jié)果:經(jīng)顱腦動態(tài)CT觀察,實(shí)驗(yàn)組犬8小時(shí)內(nèi)腦水腫出現(xiàn)時(shí)間晚于對照組,同時(shí)腦水腫程度明顯輕于對照組。 結(jié)論:海水浸泡在8小時(shí)內(nèi)可以明顯延緩腦水腫出現(xiàn)。
[Abstract]:Objective: to study the imaging characteristics of open craniocerebral explosive injury animal model under naval combat. Methods: the left (right) line of the dog's cranial midline (1 cm) and the upper orbital border (1cm) were taken as the center of the explosion. The 15 dogs were divided into three groups according to the explosion distance (the distance from the lowest point of explosion source to the explosion point). The dogs were divided into three groups: 3mm group (3.5mm) and group (4mm). The optimum explosion distance was 3.5 mm. compared with each group. Twenty dogs were randomly divided into control group (non-seawater immersion group) and experimental group (seawater immersion group). The injured brain tissue of the experimental group was immersed in seawater environment after 3.5mm injury. The dynamic changes of brain CT were compared between the two groups after 3 hours and 5 hours of injury. Results: the dynamic brain CT was observed by dynamic CT. The time of cerebral edema in the experimental group was later than that in the control group within 8 hours, and the degree of brain edema in the experimental group was significantly less than that in the control group. Conclusion: the presence of brain edema can be significantly delayed by seawater immersion within 8 hours.
【學(xué)位授予單位】:第四軍醫(yī)大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2010
【分類號】:R82;R651.15
【參考文獻(xiàn)】
相關(guān)期刊論文 前10條
1 王占江,李孝蘭,張若棋,鄭學(xué)鋒,朱玉榮,劉曉玲,胡澤根;固體介質(zhì)中球形發(fā)散波的實(shí)驗(yàn)裝置[J];爆炸與沖擊;2000年02期
2 陳海斌,王正國,楊志煥,劉寶松,李曉炎,寧心,翁格文,石林;沖擊波傳播的三個(gè)時(shí)段模擬實(shí)驗(yàn)中動物肺的損傷[J];爆炸與沖擊;2000年03期
3 王志偉,吳印愛,劉獻(xiàn)棠,謝尚奎,蔣邦好,金浩生;海水浸泡犬腹腔開放傷后血漿電解質(zhì)水平變化的實(shí)驗(yàn)研究[J];創(chuàng)傷外科雜志;2002年02期
4 王育紅,鹿?fàn)栺Z,虞積耀,王大鵬,周正謀,關(guān)淑珍;海水浸泡腹部開放性損傷對大鼠體液代謝的影響[J];第二軍醫(yī)大學(xué)學(xué)報(bào);2000年08期
5 劉銳,劉宗惠,虞積耀,王亞奇;海水浸泡對創(chuàng)傷性腦水腫影響的實(shí)驗(yàn)研究[J];第二軍醫(yī)大學(xué)學(xué)報(bào);2002年02期
6 張均奎,王正國,冷華光,楊志煥,李曉炎,尹友國,馬曉華;沖擊波負(fù)壓發(fā)生裝置及其應(yīng)用[J];第三軍醫(yī)大學(xué)學(xué)報(bào);1992年06期
7 張良潮,李曙光,凌烽,王大田,李兵倉,安波,王麗麗;一種爆炸傷致傷實(shí)驗(yàn)?zāi)P蚚J];第三軍醫(yī)大學(xué)學(xué)報(bào);1999年07期
8 陳蕾,賴西南,陳志強(qiáng),張良潮;火器傷合并海水浸泡兔肢體骨骼肌組織脂質(zhì)過氧化反應(yīng)[J];第三軍醫(yī)大學(xué)學(xué)報(bào);2000年09期
9 黃宏,王正國,賴西南,吳國萍,王麗麗,張良潮;海水浸泡彈道傷骨骼肌組織的病理變化[J];第三軍醫(yī)大學(xué)學(xué)報(bào);2001年07期
10 楊志煥,尹友國,李曉炎,翁格文,,劉大維;環(huán)境壓力對大鼠沖擊傷傷情的影響[J];第三軍醫(yī)大學(xué)學(xué)報(bào);1994年04期
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