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麻醉大鼠冰水灌耳交感神經響應在心血管調節(jié)中的作用

發(fā)布時間:2018-05-23 14:29

  本文選題:交感神經響應 + 心血管調節(jié); 參考:《航天醫(yī)學與醫(yī)學工程》2006年06期


【摘要】:目的研究冰水灌耳刺激引起的交感神經響應、心率以及血壓調節(jié)之間的內在聯(lián)系,探討前庭刺激在心血管調節(jié)中的作用。方法記錄正常麻醉(CON)大鼠(n=5)、壓力反射去除(SAD)大鼠(n=5)和迷路毀損(VD)大鼠(n=5)在冰水灌耳時內臟大神經傳出放電及血壓和心率的變化。結果正常麻醉大鼠灌耳后,血壓、心率降低,內臟大神經反應由增強到減弱。壓力反射去除大鼠灌耳后內臟大神經活動顯著高于迷路毀損大鼠,且兩組動物血壓呈相反方向變化。內臟大神經放電與呼吸的耦合形式受到灌耳刺激的影響。結論半規(guī)管輸入至少參與了血壓的短時調節(jié)機制,其作用途徑可能涉及呼吸運動的調節(jié)機制,在血壓調節(jié)中壓力反射和前庭輸入兩者作用不同,在
[Abstract]:Objective to study the relationship among sympathetic response, heart rate and blood pressure regulation induced by ice water perfusion, and to explore the role of vestibular stimulation in cardiovascular regulation. Methods the efferent discharge of splanchnic great nerve and the changes of blood pressure and heart rate were recorded in normal anaesthetized conic rats, baroreflex (SAD) rats and labyrinth (VD5) rats. Results the blood pressure and heart rate of normal anesthetized rats decreased, and the response of splanchnic great nerve increased to weaken. The splanchnic great nerve activity of the rats with baroreflex was significantly higher than that of the rats with labyrinth, and the blood pressure of the two groups was changed in the opposite direction. The coupling form of splanchnic great nerve discharge and respiration is affected by ear stimulation. Conclusion semicircular canal infusion is involved in at least the short-term regulation of blood pressure, and its mechanism may involve in the regulation of respiratory motility. In blood pressure regulation, baroreflex and vestibular infusion play different roles.
【作者單位】: 中國航天員科研訓練中心 中國航天員科研訓練中心 中國航天員科研訓練中心 中國航天員科研訓練中心 中國航天員科研訓練中心 中國航天員科研訓練中心
【基金】:總裝備部試驗技術重點課題(01101307)
【分類號】:R85

【相似文獻】

相關期刊論文 前2條

1 王林杰;董衛(wèi)軍;張丹;趙琦;仝飛舟;曹毅;;麻醉大鼠冰水灌耳交感神經響應在心血管調節(jié)中的作用[J];航天醫(yī)學與醫(yī)學工程;2006年06期

2 王林杰;董衛(wèi)軍;張丹;趙琦;仝飛舟;曹毅;;麻醉大鼠冰水灌耳交感神經響應在心血管調節(jié)中的作用[J];航天醫(yī)學與醫(yī)學工程;2006年06期

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