本文選題：乳酸林格液 + 復蘇　； 參考：《中國急救醫(yī)學》2004年10期

【摘要】：目的研究乳酸林格液復蘇對彈燒復合傷海水浸泡動物血漿電解質(zhì)及滲透壓的影響,為選擇復蘇用液體提供理論依據(jù)。方法成功建立彈燒復合傷海水浸泡動物模型后,將14只成年雜種犬隨機分為彈燒復合傷海水浸泡組(簡稱浸泡組,n=8只)和彈燒復合傷海水浸泡乳酸林格液復蘇組(簡稱復蘇組,n=6只),動態(tài)監(jiān)測傷前、傷后4,7,10,20,28h共6個時相點外周動脈血鈉、鉀、氯及血漿總滲透壓的變化。結果彈燒復合傷后海水浸泡組動物血漿電解質(zhì)及滲透壓上升非常明顯,并且貫穿在整個實驗過程;而采用乳酸林格液復蘇后,動物血漿電解質(zhì)及滲透壓明顯較浸泡組下降。結論乳酸林格液能糾正彈燒復合傷海水浸泡所出現(xiàn)嚴重的高鈉、高氯、高滲血癥。
[Abstract]:Objective to study the effect of Ringer lactate resuscitation on plasma electrolytes and osmotic pressure in marinated animals after combined bullet burn injury and to provide theoretical basis for the selection of fluid for resuscitation.Methods the animal model of projectile burn combined injury in seawater immersion was established successfully.Fourteen adult mongrel dogs were randomly divided into two groups: gunfire combined with seawater immersion group (8 dogs) and elastic burn combined injury group with lactate Ringer solution resuscitation group (6 dogs), and dynamic monitoring before injury.Changes of peripheral arterial blood sodium, potassium, chlorine and plasma total osmotic pressure at 6 time points (4: 7, 10: 20, 20: 28 h after injury).Results the plasma electrolyte and osmotic pressure in the sea water immersion group were significantly increased after the combined injury, and the plasma electrolyte and osmotic pressure were significantly decreased after the resuscitation of Ringer lactate solution in the sea water immersion group, and the plasma electrolyte and osmotic pressure in the seawater immersion group were significantly lower than those in the immersion group.Conclusion Ringer lactate solution can correct the severe hypernatremia, hyperchlorination and hyperosmosis in seawater immersion caused by bomb burn combined injury.
【作者單位】： 中國人民解放軍第三軍醫(yī)大學大坪醫(yī)院野戰(zhàn)外科研究所麻醉科 第三軍醫(yī)大學創(chuàng)傷、燒傷、復合傷國家重點實驗室戰(zhàn)傷基礎實驗室第六研究室 中國人民解放軍第三軍醫(yī)大學大坪醫(yī)院野戰(zhàn)外科研究所麻醉科
【基金】：全軍“十五”重點課題(01-L011)
【分類號】：R82

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