本文關(guān)鍵詞： 咽喉反流 質(zhì)子泵抑制劑 試驗(yàn)性治療 流行病學(xué)　出處：《青島大學(xué)》2017年碩士論文　論文類(lèi)型：學(xué)位論文

【摘要】：目的:通過(guò)對(duì)基層戰(zhàn)士咽喉反流性疾病進(jìn)行臨床流行病學(xué)調(diào)查,了解此群體中該病的發(fā)病率,同時(shí)探討生活習(xí)慣及環(huán)境等相關(guān)因素對(duì)其發(fā)病率的影響。方法:采用隨機(jī)抽樣的方法對(duì)某地2000名戰(zhàn)士于2015年10月---2016年12月進(jìn)行調(diào)查研究。將反流癥狀指數(shù)(RSI)13和/或反流體征指數(shù)(RFS)7的戰(zhàn)士作為可疑LPRD患者納入實(shí)驗(yàn)組,進(jìn)行質(zhì)子泵抑制劑(PPI)試驗(yàn)性治療,2個(gè)月后再用RSI和RFS量表對(duì)入組人群進(jìn)行評(píng)估,(若患者無(wú)明顯癥狀、RSI≤10,喉部檢查正常、RFS≤5),就可以明確診斷,從而獲得該人群發(fā)病率。對(duì)海軍、陸軍不同軍種及艇上、岸上不同環(huán)境的戰(zhàn)士發(fā)病率進(jìn)行比較。并對(duì)相關(guān)發(fā)病因素進(jìn)行因子分析的主成分分析。結(jié)果:2000名戰(zhàn)士(海軍1000人,陸軍1000人)經(jīng)RSI及RFS量表評(píng)分后,可疑病例為93例(4.65%),對(duì)其進(jìn)行PPI試驗(yàn)性治療后,72例確診為L(zhǎng)PRD,該群體發(fā)病率為3.60%。1000名海軍中患病47人,發(fā)病率4.70%;1000名陸軍中患病25人,發(fā)病率2.50%;軍兵種之間發(fā)病率差異有統(tǒng)計(jì)學(xué)意義(X2=6.9733,P=0.0083)。艇上戰(zhàn)士487人,患病33人,發(fā)病率6.78%;岸上戰(zhàn)士1513人,患病39人,發(fā)病率2.58%;艇上和岸上戰(zhàn)士發(fā)病率差異有統(tǒng)計(jì)學(xué)意義(X2=18.7133,P=0.0000)。對(duì)于發(fā)病因素吸煙、高脂飲食、情緒、濃茶、咖啡、便秘、生活環(huán)境等主成分均有相關(guān)性。結(jié)論:某地戰(zhàn)士LPRD的發(fā)病率較普通人群明顯低,但該疾病仍客觀(guān)存在于基層部隊(duì)中,理應(yīng)引起各軍事單位的重視。軍人LPRD的發(fā)生與工作環(huán)境、生活習(xí)慣、心理應(yīng)激等關(guān)系密切。日常應(yīng)注重LPRD相關(guān)知識(shí)的宣教,對(duì)于今后積極防治LPRD及其并發(fā)癥的發(fā)生,從而降低部隊(duì)的非戰(zhàn)斗減員有舉足輕重的意義。
[Abstract]:Objective: to investigate the incidence of pharynx and larynx reflux disease in this population. At the same time, the influence of related factors, such as living habits and environment, on the incidence of disease was discussed. Methods: a random sampling method was used to investigate 2 000 soldiers from October 2015 to December 2016. The reflux symptom index (RSI13) and / or. Soldiers who had a sign index of regurgitation or RFS7 were included in the experimental group as suspected LPRD patients. Proton pump inhibitor (PPI) was used as experimental therapy. After 2 months, the patients were evaluated with RSI and RFS scale. (if the patients had no obvious symptoms, RSI 鈮，

本文編號(hào)：1534953