馬拉松膝關(guān)節(jié)軟骨MR定量研究及軟骨自動(dòng)分割軟件的臨床效能評(píng)估
發(fā)布時(shí)間:2021-11-11 09:56
隨著生活水平和健康觀念的提升,長(zhǎng)跑已經(jīng)成為一種流行的娛樂(lè)活動(dòng),我國(guó)馬拉松賽事的舉辦逐年增加。據(jù)統(tǒng)計(jì),2017年全國(guó)各地共舉辦馬拉松及相關(guān)運(yùn)動(dòng)賽事1100場(chǎng),在2011-2017年間,賽事場(chǎng)次增加了五十多倍。由于缺乏專業(yè)的跑步知識(shí)和系統(tǒng)的指導(dǎo),跑步者在跑步過(guò)程中很容易出現(xiàn)損傷,其中膝關(guān)節(jié)的損傷概率最高。馬拉松影像研究在國(guó)外數(shù)量不多,在國(guó)內(nèi)幾乎空白。本研究通過(guò)T2 mapping成像觀察馬拉松前后膝關(guān)節(jié)軟骨T2值的變化,評(píng)價(jià)跑者在馬拉松后是否會(huì)出現(xiàn)膝關(guān)節(jié)軟骨的損傷。在常規(guī)的MR圖像中,我們僅能得到一些二維信息,并且測(cè)量定量的數(shù)值如T2、T2*值要進(jìn)行每個(gè)層面的手動(dòng)勾畫(huà),而三維重建圖像克服了常規(guī)二維圖像的不足,本研究利用膝關(guān)節(jié)軟骨自動(dòng)分割軟件(Siemens Chondral Health,Version 2.1,Siemens Healthcare,Erlangen,Germany)獲得軟骨T2*值及軟骨體積值,進(jìn)行手動(dòng)校正后,驗(yàn)證該軟件的臨床應(yīng)用價(jià)值。第一部分應(yīng)用T2 mapping成像評(píng)價(jià)馬拉松前后膝關(guān)節(jié)軟骨短中期改變目的:應(yīng)用T2 mapping成像評(píng)價(jià)非專業(yè)長(zhǎng)跑者馬拉松前后膝關(guān)節(jié)軟...
【文章來(lái)源】:河北醫(yī)科大學(xué)河北省
【文章頁(yè)數(shù)】:55 頁(yè)
【學(xué)位級(jí)別】:碩士
【部分圖文】:
正常膝關(guān)節(jié)軟骨MRI圖像
19圖2正常膝關(guān)節(jié)軟骨MRI圖像Fig.2MRIimagingofnormalkneecartilageDuringthepre-competition(a),post-competition(b)and2monthsafterthecompetition(c),therewasnoobviousabnormalsignalinthekneecartilage.Thecartilagewasintactwithsmoothsurface.Theshapeandsignalofthemeniscus,ligamentsandtendonswerenormal.Therewasnoeffusionandcorpusliberuminarticularcapsule.圖3骨髓水腫MRI圖像Fig.3MRIimagingofbonemarrowedemaOnevolunteerhadbonemarrowedemainthedistalfemurandproximaltibiabeforetherace(a).Aftertherace,therangeofedemawasslightlyreducedandthesignalintensitywasweakened(b).Bonemarrowedemawaslargelydisappearedafter2monthsoffollow-up(c).2.關(guān)節(jié)軟骨T2值改變關(guān)節(jié)軟骨淺層T2值在賽前、賽后12h內(nèi)及2個(gè)月隨訪時(shí)均高于深層(t值分別為11.095、10.385、10.102,P值均<0.01),差異有統(tǒng)計(jì)學(xué)意義。與賽前相比,賽后12h內(nèi)關(guān)節(jié)軟骨淺層T2值降低,差異有統(tǒng)計(jì)學(xué)意義;賽后2個(gè)月隨訪時(shí),差異無(wú)統(tǒng)計(jì)學(xué)意義(見(jiàn)表2)。而深層區(qū)域整體軟骨T2值在賽后12h內(nèi)及賽后2個(gè)月隨訪時(shí)與賽前相比,差異均無(wú)統(tǒng)計(jì)學(xué)意義(見(jiàn)abcabc
378,0.028*1.488,0.153,147,0.005*0.467,0.645-0.594,0.5600.559,0.581-1.135,0.2710.849,0.405-0.812,0.4270.797,0.434-0.519,0.607Note:T2(ms)valuesarepresentedasmean±standarddeviation.*Significantdifference(P<0.05)SZ:superficialzoneofkneecartilage,DZ:deepzoneofkneecartilage,MTP:medialtibialplateau,LTP:lateraltibialplateau,MFC:medialfemoralcondyle,LFC:lateralfemoralcondyle,1:pre-competition,2:within12hafterthecompetition,3:twomonthsafterthecompetition.圖4三次掃描膝關(guān)節(jié)淺層軟骨T2值變化趨勢(shì)圖Fig.4TendencychartofT2valueinsuperficialcartilageofkneeFromtheresultsofthreescans,wecanseethatT2valueofthemostsuperficialcartilageofkneejointshowedatendencyof"descendingfirstandthenrising",however,theT2valueintheLFCandMFCcartilagesubregion
本文編號(hào):3488653
【文章來(lái)源】:河北醫(yī)科大學(xué)河北省
【文章頁(yè)數(shù)】:55 頁(yè)
【學(xué)位級(jí)別】:碩士
【部分圖文】:
正常膝關(guān)節(jié)軟骨MRI圖像
19圖2正常膝關(guān)節(jié)軟骨MRI圖像Fig.2MRIimagingofnormalkneecartilageDuringthepre-competition(a),post-competition(b)and2monthsafterthecompetition(c),therewasnoobviousabnormalsignalinthekneecartilage.Thecartilagewasintactwithsmoothsurface.Theshapeandsignalofthemeniscus,ligamentsandtendonswerenormal.Therewasnoeffusionandcorpusliberuminarticularcapsule.圖3骨髓水腫MRI圖像Fig.3MRIimagingofbonemarrowedemaOnevolunteerhadbonemarrowedemainthedistalfemurandproximaltibiabeforetherace(a).Aftertherace,therangeofedemawasslightlyreducedandthesignalintensitywasweakened(b).Bonemarrowedemawaslargelydisappearedafter2monthsoffollow-up(c).2.關(guān)節(jié)軟骨T2值改變關(guān)節(jié)軟骨淺層T2值在賽前、賽后12h內(nèi)及2個(gè)月隨訪時(shí)均高于深層(t值分別為11.095、10.385、10.102,P值均<0.01),差異有統(tǒng)計(jì)學(xué)意義。與賽前相比,賽后12h內(nèi)關(guān)節(jié)軟骨淺層T2值降低,差異有統(tǒng)計(jì)學(xué)意義;賽后2個(gè)月隨訪時(shí),差異無(wú)統(tǒng)計(jì)學(xué)意義(見(jiàn)表2)。而深層區(qū)域整體軟骨T2值在賽后12h內(nèi)及賽后2個(gè)月隨訪時(shí)與賽前相比,差異均無(wú)統(tǒng)計(jì)學(xué)意義(見(jiàn)abcabc
378,0.028*1.488,0.153,147,0.005*0.467,0.645-0.594,0.5600.559,0.581-1.135,0.2710.849,0.405-0.812,0.4270.797,0.434-0.519,0.607Note:T2(ms)valuesarepresentedasmean±standarddeviation.*Significantdifference(P<0.05)SZ:superficialzoneofkneecartilage,DZ:deepzoneofkneecartilage,MTP:medialtibialplateau,LTP:lateraltibialplateau,MFC:medialfemoralcondyle,LFC:lateralfemoralcondyle,1:pre-competition,2:within12hafterthecompetition,3:twomonthsafterthecompetition.圖4三次掃描膝關(guān)節(jié)淺層軟骨T2值變化趨勢(shì)圖Fig.4TendencychartofT2valueinsuperficialcartilageofkneeFromtheresultsofthreescans,wecanseethatT2valueofthemostsuperficialcartilageofkneejointshowedatendencyof"descendingfirstandthenrising",however,theT2valueintheLFCandMFCcartilagesubregion
本文編號(hào):3488653
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