【摘要】：正德國研究人員在該學會的《核子醫(yī)學雜志》上報道,他們發(fā)明了一種新型對比劑,結合現(xiàn)有的正電子掃描技術,可以發(fā)現(xiàn)多個部位的微小血栓。這種對比劑稱為18F-GP1,它是一種特殊的小分子,用氟元素的放射性同位素18F標記。通過靜脈注射進入血液系統(tǒng)后,這種分子能有針對性地與血小板膜糖蛋白GPⅡb/Ⅲa緊密結合,后者參與血小板的聚集與活化,促進血栓形成。18F是一種很好的正電子來源,用正電子發(fā)射計算機斷層掃描很容易發(fā)現(xiàn)它。
[Abstract]:Researchers in Germany reported in the Society's Journal of Nuclear Medicine that they have developed a new contrast agent that, combined with existing positron scanning techniques, can detect tiny thrombosis at multiple sites. The contrast, called 18F-GP1, is a special small molecule labeled with fluorine radioisotope 18F. After intravenous injection into the blood system, the molecule binds closely to platelet membrane glycoprotein GP 鈪，

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