發(fā)布時(shí)間：2018-08-15 11:22

【摘要】：目的:探討降低輻射劑量方法結(jié)合運(yùn)用低濃度對比劑進(jìn)行肝臟CT動(dòng)態(tài)增強(qiáng)掃描臨床應(yīng)用的可行性。方法:180例受檢者首先根據(jù)使用碘克沙醇劑量的不同隨機(jī)分為I組(270 mg I/m L碘克沙醇)和II組(320 mg I/m L碘克沙醇),然后將A(120 k V/300 m A),B(100 k V/400 m A),C(100 k V/300 m A)3組不同的掃描條件隨機(jī)分布于I組和II組各期(動(dòng)脈期、靜脈期、延時(shí)期)的動(dòng)態(tài)增強(qiáng)掃描中;記錄、統(tǒng)計(jì)并比較各組有效輻射劑量(eff ective radiation dose,ED)、圖像CT值及反映圖像質(zhì)量的噪聲值(image of noise,NI)、信噪比(signal to noise ratio,SNR)、對比噪聲比(contrast to noise ratio,CNR)、整體圖像質(zhì)量(overall image quality,OIQ)。結(jié)果:總體樣本中C組的ED值比A組在3期動(dòng)態(tài)增強(qiáng)掃描中分別降低約38%,40%,41%,圖像質(zhì)量各值(NI,SNR,CNR,OIQ)兩組間差異有統(tǒng)計(jì)學(xué)意義(P0.05);B組的ED值比A組在3期動(dòng)態(tài)增強(qiáng)掃描中分別降低約18%,20%,20%,而圖像質(zhì)量各值均無明顯差異(P0.05)。同掃描條件及時(shí)相下I,II兩組圖像CT值存在明顯差異(P0.05)而圖像質(zhì)量各值無明顯差異(P0.05);A-II組與B-I,C-I組圖像CT值無明顯差異(P0.05);所得圖像質(zhì)量各值A(chǔ)-II組與B-I組無明顯差異(P0.05),但A-II組與C-I組差異明顯(P0.05)。結(jié)論:通過降低管電壓適當(dāng)提高管電流結(jié)合應(yīng)用低濃度對比劑,肝臟CT動(dòng)態(tài)增強(qiáng)掃描圖像質(zhì)量可滿足診斷,同時(shí)降低了輻射劑量及對比劑劑量。
[Abstract]:Objective: to investigate the feasibility of dynamic enhanced CT scanning of liver by reducing radiation dose and using low concentration contrast agent. Methods: one hundred and eighty subjects were randomly divided into two groups: group I (270 mg I / ml) and group II (320 mg I / m L iodoxanol), then A (120kV / 300 m A) B) (100kV / 400 m A) C) were scanned with different scans. The mapping conditions were randomly distributed in groups I and II (arterial phase). In the dynamic enhancement scan of the venous phase, delay period; record, The effective radiation dose (eff ective radiation doseed), image CT value and noise value (image of noisegni), signal-to-noise ratio (SNR), (contrast to noise ratiogna (contrast to noise), and overall image quality (overall image quality) were analyzed and compared in each group. Results: the Ed value of group C was lower than that of group A in 3 phase dynamic contrast-enhanced scanning. There were significant differences between the two groups in image quality (NINRRX CNRIQ). (P0.05) Ed in group B was significantly lower than that in group A in dynamic enhanced scan (group A). There was a significant difference between the two groups in image quality (NINRRX CNRIQ) (P0.05). The Ed of group B was significantly lower than that of group A (P < 0.05). There was no significant difference in image quality (P0.05). Under the same scanning condition, there was significant difference in CT value between the two groups (P0.05), but there was no significant difference in image quality between A-II group and B-IC-I group (P0.05), and there was no significant difference in image quality between A-II group and B-I group (P0.05), but there was no significant difference in CT value between B-IC-I group and A-II group (P0.05), but there was no significant difference in CT value between B-I group and A-II group (P0.05). There was significant difference between A-II group and C-I group (P0.05). Conclusion: by decreasing the voltage of the tube and increasing the current of the tube and applying low concentration contrast agent, the quality of dynamic enhanced CT scan image of liver can be satisfied with the diagnosis, and the dose of radiation and contrast agent can be reduced at the same time.
【作者單位】： 中南大學(xué)湘雅醫(yī)學(xué)院附屬�？卺t(yī)院放射科;
【基金】：海南省衛(wèi)生廳項(xiàng)目(瓊衛(wèi)2011-66) �？谑兄攸c(diǎn)科技項(xiàng)目(2011-0144)~~
【分類號】：R816.5;R575

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