本文選題：淋巴瘤 + 惡性胸腺瘤��； 參考：《山西醫(yī)科大學》2013年碩士論文

【摘要】：目的： 通過測量和分析惡性胸腺瘤及縱隔淋巴瘤患者不同單能量下病變部位單能量圖像的CT值及碘水含量、水含量,探討CT能譜成像在鑒別惡性胸腺瘤和縱隔淋巴瘤中的價值。 方法： 回顧性分析行能譜CT檢查并經(jīng)手術(shù)切除或穿刺活檢證實的的惡性胸腺瘤20例及縱隔淋巴瘤15例,在手術(shù)或穿刺活檢前,均運用寶石能譜CT的能譜掃描模式進行平掃及增強掃描,圖像在能譜成像瀏覽器(GSI viewer)軟件下觀察,運用分析工具分析病變部位的能譜曲線,測量不同單能量(40keV-140keV)下的CT值,并在物質(zhì)分離圖像上測量病變部位的碘含量及水含量,對數(shù)據(jù)進行分析及獨立樣本t檢驗。 結(jié)果： 平掃時惡性胸腺瘤組在40-50KeV能量水平的CT值明顯低于縱隔淋巴瘤組,而在90-140KeV能量水平的CT值明顯高于縱隔淋巴瘤組,差異有統(tǒng)計學意義。惡性胸腺瘤組能譜曲線斜率(0.23±0.06)明顯低于縱隔淋巴瘤組(0.36±0.07),差異有統(tǒng)計學意義(t=2.681,p=0.012)。 增強掃描后惡性胸腺瘤組在40-100KeV能量水平的CT值明顯高于縱隔淋巴瘤組,差異有統(tǒng)計學意義；惡性胸腺瘤組能譜曲線斜率(1.32±0.42)明顯低于縱隔淋巴瘤組(1.01±0.1),差異有統(tǒng)計學意義(t=2.681,p=0.015)。惡性胸腺瘤組的碘含量(1.75±0.53)g/L、水含量(1042.38±5.02)g/L明顯高于縱隔淋巴瘤組(1.34±0.19)g/L,(1036.50±7.08)g/L差異亦有統(tǒng)計學意義。 結(jié)論： 寶石CT的能譜成像技術(shù)可以進行單能量能譜衰減曲線分析和碘含量、水含量分析,對惡性胸腺瘤及縱隔淋巴瘤的鑒別有一定意義。 CT能譜成像技術(shù)操作簡便,能夠廣泛應用于臨床。
[Abstract]:Objective: to measure and analyze the CT value and iodine water content of lesions in patients with malignant thymoma and mediastinal lymphoma under different single energy. To study the value of CT energy spectrum imaging in differentiating malignant thymoma from mediastinal lymphoma. Methods: twenty cases of malignant thymoma and 15 cases of mediastinal lymphoma confirmed by excision or puncture biopsy were analyzed retrospectively. The scanning mode of gem energy spectrum CT was used for plain scan and enhancement scan. The image was observed by the software of energy spectrum imaging browser (GSI viewer). The spectral curve of lesion was analyzed by means of analysis tools, and the CT value of different single energy (40keV-140keV) was measured. The iodine content and water content of the lesion were measured on the material separation image, and the data were analyzed and independent sample t-test. Results: the CT value of 40 ~ 50 KeV energy level in malignant thymoma group was significantly lower than that in mediastinal lymphoma group, but the CT value in 90-140 Kev energy level was significantly higher than that in mediastinal lymphoma group. The slope of energy spectrum curve in malignant thymoma group (0.23 鹵0.06) was significantly lower than that in mediastinal lymphoma group (0.36 鹵0.07). The CT value of 40 ~ 100 KeV energy level in malignant thymoma group was significantly higher than that in mediastinal lymphoma group, and the slope of energy spectrum curve in malignant thymoma group (1.32 鹵0.42) was significantly lower than that in mediastinal lymphoma group (1.01 鹵0.1). The iodine content (1.75 鹵0.53) g / L and water content (1042.38 鹵5.02) g / L in malignant thymoma group were significantly higher than those in mediastinal lymphoma group (1.34 鹵0.19) g / L and (1036.50 鹵7.08) g / L respectively. Conclusion: the single energy spectrum attenuation curve, iodine content and water content can be analyzed by the energy spectrum imaging technique of gemstone CT. It is useful for the differential diagnosis of malignant thymoma and mediastinal lymphoma. The technique of CT energy spectrum imaging is easy to operate and can be widely used in clinic.
【學位授予單位】：山西醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2013
【分類號】：R730.44;R734.5;R736.3

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