本文選題：冠狀動脈疾病 + 心包��； 參考：《中國臨床醫(yī)學(xué)影像雜志》2015年03期

【摘要】：目的:探討CT測量心外膜脂肪組織的密度與冠狀動脈粥樣硬化斑塊的關(guān)系。方法:417例疑似冠心病患者行多螺旋CT造影檢查,精確測量相應(yīng)心外膜脂肪密度。根據(jù)造影檢查結(jié)果分為斑塊組及非斑塊組,并進(jìn)一步將斑塊組分為3個亞組,即鈣化斑塊組、混合斑塊組、非鈣化斑塊組,并按照不同性別和年齡分組,比較斑塊側(cè)與非斑塊側(cè)心外膜脂肪密度。結(jié)果:1417例患者納入研究,其中斑塊組189例,其中鈣化斑塊者42例,非鈣化斑塊59例,混合斑塊83例;無斑塊者228例。2斑塊側(cè)心外膜脂肪密度(以CT值比較)高于非斑塊側(cè),兩者之間存在統(tǒng)計學(xué)差異(40.84±37.28 vs.23.81±30.81,P=0.000),無論男性還是女性,斑塊側(cè)心外膜脂肪密度均高于非斑塊側(cè)(男,t=8.78,P=0.000;女,t=5.941,P=0.000);按年齡分層后,心外膜脂肪密度在45歲組以下(t=7.012,P=0.000)、45~55歲組(t=3.459,P=0.002)、55~65歲組(t=5.416,P=0.000)、65歲以上組(t=7.750,P=0.000)均為斑塊組大于非斑塊組,均存在統(tǒng)計學(xué)意義;斑塊側(cè)與非斑塊側(cè)心外膜脂肪密度均以非鈣化斑塊組的值最高,鈣化斑塊組最低,差異有統(tǒng)計學(xué)意義。相同性質(zhì)各斑塊組內(nèi)斑塊側(cè)心外膜脂肪密度均大于非斑塊側(cè),差異有統(tǒng)計學(xué)意義。結(jié)論:心外膜脂肪密度與冠狀動脈粥樣硬化斑塊形成存在密切關(guān)系,與斑塊性質(zhì)有關(guān)。
[Abstract]:Objective: to investigate the relationship between density of epicardial adipose tissue and coronary atherosclerotic plaque measured by CT. Methods multihelical CT angiography was performed in 417 patients with suspected coronary heart disease and the epicardial fat density was measured accurately. The plaque group was further divided into three subgroups: calcified plaque group, mixed plaque group, non-calcified plaque group, and divided into three groups according to sex and age. The epicardial fat density of plaque side and non plaque side was compared. Results one hundred and seventeen patients were included in the study, including 189 cases in plaque group, 42 cases in calcified plaque, 59 cases in non-calcified plaque, 83 cases in mixed plaque, 228 cases without plaque, 228 cases with plaque side, the epicardial fat density (compared with CT value) was higher than that in non-plaque side. There was a statistical difference between the two groups (40.84 鹵37.28 vs.23.81 鹵30.81P0.000). The epicardial fat density of plaque side was higher in male and female than that in non-plaque side (male = 8.78 P0.000; female = 5.941 P = 0.000); after age stratification, the density of epicardial fat in plaque side was higher than that in non-plaque side. The density of epicardial fat under 45 years old group (tn 7.012 P0. 000) and 45 + 55 years old group (tng 3. 459 P0. 002) 55 years old group (t 5. 416 P0. 000) and above 65 years old group (t0. 750 P0. 000) were all higher than that of non-plaque group, and there was statistical significance in both plaque side and non-plaque epicardial membrane fat density in non-calcified plaque group, the highest in non-calcified plaque group, and there was no significant difference between non-calcified plaque group and non-calcified plaque group in both plaque side and non-plaque group Calcified plaque group was the lowest, the difference was statistically significant. The epicardial fat density of the plaque side in the same plaque group was higher than that in the non-plaque side, and the difference was statistically significant. Conclusion: epicardial fat density is closely related to the formation of coronary atherosclerotic plaque and related to the nature of plaque.
【作者單位】： 河北聯(lián)合大學(xué)附屬開灤總醫(yī)院影像科;
【分類號】：R541.4;R816.2

【參考文獻(xiàn)】

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1 周亮亮;王t，

本文編號：2080853