本文選題：計算機體層成像 + 低管電壓��； 參考：《山東大學》2014年博士論文

【摘要】：一、MSCT低管電壓掃描對比劑劑量優(yōu)化的實驗研究 目的：探討與低管電壓(kVp) CT掃描技術(shù)匹配的對比劑劑量。材料方法：配制不同對比劑含量的混合溶液(對比劑和生理鹽水,單位ml,對比劑為碘海醇300mgI/ml),分別裝入5只試管內(nèi),0號試管對比劑含量為2%,1-4號管對比劑含量依次較0號試管減少10%,20%,30%,40%,分別為1.8%、1.6%、1.4%、1.2%,再裝入標準腹部體膜小孔內(nèi),分別行90kVp和120kVp腹部條件掃描,分別測量5只試管內(nèi)對比劑溶液的CT值,比較不同對比劑含量溶液90kVp管電壓時的CT值,以及90kVp各不同對比劑含量溶液的CT值與120kVp0試管對比劑溶液CT值的差異,進行統(tǒng)計學分析。結(jié)果：90kVp條件下,0-4號試管的CT值隨著對比劑劑量的減少而降低,0和1號試管內(nèi)對比劑溶液的CT值無統(tǒng)計學意義,0、1與2、3、4號試管間對比劑溶液CT值有統(tǒng)計學意義。90kVp條件下,0、1、2號試管內(nèi)對比劑溶液的CT值均高于120kVp的0號管,90kVp條件下的3、4號管(即對比劑劑量減少30-40%)對比劑溶液CT值與120kVp的0號管對比劑溶液CT值間無統(tǒng)計學差異,但輻射劑量降低約33%。結(jié)論：低管電壓掃描時減少30-40%的對比劑劑量,可以達到常規(guī)掃描模式的強化效果,同時輻射劑量降低33%。 二、MSCT低管電壓掃描門靜脈成像延遲時間的選擇 目的：探討MSCT90kVp門靜脈成像延遲時間的選擇。材料方法：46例行腹部CT強化掃描的患者,隨機分為A、B兩組,每組23例,均行9OkVp.395mAs腹部掃描,對比劑為碘海醇300mgI/ml,注射劑量為1.2ml/kg,速率3.0ml/s,行門脈期掃描時延遲時間分別為A組50s,B組60s,選取門脈期圖像進行分析,分別測量肝實質(zhì)及門靜脈CT值,比較A、B兩組患者肝實質(zhì)CT值、門靜脈CT值及不同延遲時間肝實質(zhì)和門靜脈CT值差值,進行統(tǒng)計分析。結(jié)果：A組門靜脈平均CT值為197.2±27.2Hu,B組為178.3±24.0Hu,A組高于B組,二者有統(tǒng)計學差異；A組肝實質(zhì)平均CT值為109.8±15.3Hu,B組肝實質(zhì)平均CT值為108.4±12.9Hu,二者無統(tǒng)計學差異；A、B兩組門靜脈與肝實質(zhì)的差值分別為87.4±23.8Hu,69.9±30.8Hu,A組高于B組,二者差異有統(tǒng)計學意義。結(jié)論：90kVp低管電壓腹部CT掃描,門靜脈成像延遲時間50s強化效果優(yōu)于60s。異；ED分別為3.8±O.4mSv,5.7±0.5mSv,二者有統(tǒng)計學差異,90kVp組輻射劑量減少了33%。結(jié)論：MSCT雙低掃描可用于正常體質(zhì)量指數(shù)患者的門靜脈成像,且門靜脈顯示優(yōu)于常規(guī)掃描,同時降低了輻射劑量,減少了對比劑用量。
[Abstract]:Experimental study on dose optimization of MSCT low tube voltage scanning contrast agent objective: to study the dose of contrast agent matching with low tube voltage (KVP) CT scanning technique. Materials methods: mixed solutions with different contents of contrast agents (contrast agent and saline) were prepared. In unit ml, the contrast agent was iodiol 300mgI / ml, which was put into 5 test tubes, respectively. The contrast agent content in tube 0 was 2X 1-4. The content of contrast agent in tube No. 0 was decreased by 10% 2020% 30% and 40g / ml, respectively, which was 1.8% 1.6% 1. 2% and 1. 2% respectively, and then loaded into the small hole of the standard abdominal membrane. The CT values of contrast medium solution in 5 test tubes were measured by abdominal conditional scanning of 90 kV p and 120 kV p, respectively, and the CT values of 90 kV P tube voltage with different contrast agent contents were compared. The difference of CT value between 90 KVP and 120 kVp0 contrast solution was analyzed statistically. Results under the condition of 90 KVP, the CT value of the test tube No. 0-4 decreased with the decrease of the dose of contrast agent. There was no significant difference between the CT value of the contrast medium solution in the 0 and 1 tubes. The CT value of the contrast medium solution in the test tube No. 4 was significantly higher than that in the control tube. The CT value of the contrast medium solution in the test tube No. 4 was significantly higher than that in the control tube. The CT value of contrast agent solution in tube No. 1 and No. 2 was higher than that in tube No. 0 with 120kVp. There was no significant difference between CT value of contrast medium solution and CT value of tube No. 0 contrast agent solution with 120kVp. The CT value of contrast agent solution in tube No. 4 (30-40% reduction of contrast agent dose) was higher than that in tube No. 0 tube with 120kVp, and the CT value of contrast agent solution in tube No. 2 was higher than that in tube No. 0 with 120kVp. But the radiation dose was reduced by about 33. Conclusion: the enhancement effect of conventional scanning mode can be achieved by reducing the dose of contrast agent by 30-40% while reducing the radiation dose by 33% during low-tube voltage scanning. The selection of delayed time of MSCT low-tube voltage scanning portal vein imaging objective: to explore the choice of delayed time of MSCT 90kVp portal vein imaging. Materials: methods Forty-six patients with abdominal CT enhanced scanning were randomly divided into two groups: group A (n = 23) and group B (n = 23), all of whom underwent 9OkVp.395mAs abdominal scan. The contrast medium was 300 mg I / ml, the dose was 1.2 ml / kg, the rate was 3.0 ml / s, and the delayed time of portal phase scanning was 60 s in group A and group B, respectively. The portal phase images were selected to analyze the CT value of hepatic parenchyma and portal vein, and the CT values of hepatic parenchyma were compared between the two groups. Ct value of portal vein, hepatic parenchyma and CT value of portal vein at different delay time were statistically analyzed. Results the average CT value of portal vein in group A was 197.2 鹵27.2Huao B (178.3 鹵24.0Huao) was higher than that in group B (P < 0.05). There was significant difference between the two groups. The mean CT value of hepatic parenchyma in group A was 109.8 鹵15.3Hu.There was no significant difference between the two groups in CT value of hepatic parenchyma. The difference between portal vein and hepatic parenchyma in group A was higher than that in group B (87.4 鹵23.8Huan69.9 鹵30.8HuA, respectively), and the difference between group A and group B was statistically significant. Conclusion the enhancement effect of CT scan with low voltage abdominal CT scan at 90 KVP is better than that of 60 s with delayed time 50 s in portal vein imaging. Ed was 3.8 鹵0.4 mSvN 5.7 鹵0.5 mSv, respectively. The radiation dose of 90kVp group was decreased by 33%. Conclusion dual low volume MSCT scan can be used for portal vein imaging in patients with normal body mass index, and portal vein display is superior to conventional scanning, and radiation dose is reduced and contrast agent dosage is reduced.
【學位授予單位】：山東大學
【學位級別】：博士
【學位授予年份】：2014
【分類號】：R816.2

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