本文選題：計算機體層攝影 + 迭代重建　； 參考：《貴州醫(yī)科大學》2017年碩士論文

【摘要】：目的:探討正弦圖確定迭代重建(sinogram affirmed iterative reconstruction,SAFIRE)技術在肝臟低kVpCT增強掃描中的價值。方法:收集貴州醫(yī)科大學附屬醫(yī)院2015年7月~2016年6月以各種原因行上腹部CT增強掃描的受檢者59例,回顧性分析其影像學檢查及臨床資料,按照掃描時的管電壓不同分為A組(120kVp)和B組(80kVp),A組29例,男性16例,女性13例,年齡39~79歲,平均年齡(55.79±10.96)歲;B組30例,男性18例,女性12例,年齡32~79歲,平均年齡(56.93±13.71)歲,所有受檢者的身體質量指數(shù)(body mass index,BMI)均在18.5~24kg/m2。所有受檢者均采用德國西門子公司SIEMENS128層SOMATOM Definition AS+螺旋CT掃描儀進行掃描。均采用軸位掃描,掃描范圍自膈頂至肝下緣。A組(n=29)采用120kVp條件掃描后,對動脈期原始圖像進行濾波反投影重建(filtered back projection,FBP),B組(n=30)采用80kVp條件掃描后,對動脈期原始圖像進行SAFIRE重建,重建級別為1~5級,分別編號為B1~B5組,共得到6組重建圖像,卷積核分別為B40f及I40f,重建層厚為1.0mm,間隔為1.0mm,在西門子后處理工作站Syngo MMWP(Version 2008A)上進行數(shù)據(jù)分析測量。在動脈期圖像中選擇肝門層面,測量肝臟CT值、空氣CT值。記錄CT設備上提供的掃描時的容積CT劑量指數(shù)(Volume CT dose index,CTDIvol)和劑量長度乘積(dose length product,DLP)。比較A、B兩組輻射劑量以及圖像質量的評價指標。輻射劑量評價指標包括:CTDIvol、DLP及有效劑量(effective dose,ED);圖像質量的客觀評價指標包括:肝實質CT值、圖像噪聲及信噪比(signal to noise ratio,SNR);圖像質量的主觀評價指標包括:對圖像噪聲、血管顯示、偽影及圖像整體質量進行主觀評分。采用SPPSS19.0軟件進行統(tǒng)計學分析,采用獨立樣本t檢驗對A、B兩組的輻射劑量評價指標CTDIvol、DLP及ED進行比較;采用方差分析對6組圖像的客觀評價指標及主觀評價指標進行組間比較,組內多重比較采用LSD法。結果:A、B兩組輻射劑量評價指標CTDIvol、DLP及ED差異均有統(tǒng)計學意義(P均㩳0.05),B組的ED較A組約減少了40.33%。6組圖像肝實質CT值差異無統(tǒng)計學意義(P均㧐0.05)、SD及SNR差異均有統(tǒng)計學意義(P均㩳0.05),兩兩比較發(fā)現(xiàn),B1~B5組與A組圖像肝臟CT值差異均有統(tǒng)計學意義(P均㩳0.05),而B組(B1~B5組)肝實質CT值組內比較,差異均無統(tǒng)計學意義(P均㧐0.05),B3~B5組與A組圖像SD及SNR差異均有統(tǒng)計學意義(P均㩳0.05),B5組與其他各組的SD及SNR差異均有統(tǒng)計學意義(P均㩳0.05),說明B5組圖像的SD最小,SNR最大。6組圖像的主觀評分差異均有統(tǒng)計學意義(P均㩳0.05),兩兩比較發(fā)現(xiàn),B5組圖像的噪聲、血管顯示及硬化偽影的得分均高于其他各組(P均㩳0.05),但“臘樣”偽影的得分均低于其他各組(P均㩳0.05),B3組重建圖像的整體評分最高(P均㩳0.05)。結論:80kVp肝臟CT增強掃描結合SAFIRE-3重建技術,能得到較好的圖像質量,同時能夠降低有效輻射劑量。
[Abstract]:Objective: to investigate the value of sinogram affirmed iterative reconstructionsSAFIREE technique in liver low-kVpCT enhanced scanning. Methods: a total of 59 patients with upper abdominal CT enhanced scanning from July 2015 to June 2016 in affiliated Hospital of Guizhou Medical University were collected and their imaging and clinical data were analyzed retrospectively. They were divided into two groups: group A (n = 29) and group B (n = 29). There were 16 males, 13 females, aged 390.79 years, with an average age of 55.79 鹵10.96 years, 30 patients in group B, 18 males and 12 females, aged 3279 years with an average age of 56.93 鹵13.71), were divided into two groups: group A (n = 30) and group B (n = 29). Body mass index (BMI) of all participants was 18.5kg / m ~ (2) at 24 kg / m ~ (2). All the subjects were scanned by Siemens 128 layer SOMATOM definition as spiral CT scanner. All of them were scanned by axial scan. The scanning range was from the top of the diaphragm to the lower hepatic margin. Group A was scanned with 120kVp condition. The original images of arterial phase were reconstructed by filtered back projection. Group B was scanned with 80kVp condition, and the original images of arterial phase were reconstructed with SAFIRE. The reconstruction grade was 1 / 5 and numbered B1 / B5 respectively. Six groups of reconstructed images were obtained. The convolution cores were B40f and I40f.The reconstruction layer thickness was 1.0 mm and the interval was 1.0 mm. The data were analyzed and measured on Syngo MMWPPU version 2008A, a Siemens post processing workstation. Hepatic CT value and air CT value were measured on hilar plane in arterial phase image. The volume CT dose index (CTDIvoll) and dose length product (DLP) were recorded. The radiation dose and image quality of two groups of Agna B were compared. The evaluation indexes of radiation dose include: 1: CTDIvoll DLP and effective dose DLP, the objective evaluation indexes of image quality include: Ct value of liver parenchyma, image noise and signal-to-noise ratio signal to noise signal to SNR, subjective evaluation index of image quality include: image noise, vascular display. Artifact and overall image quality were evaluated subjectively. SPPSS 19.0 software was used to carry on the statistical analysis, the independent sample t test was used to compare the radiation dose evaluation index CTDIvoll DLP and Ed of the two groups, the objective evaluation index and the subjective evaluation index of the six groups were compared with each other by the analysis of variance. Multiple intra-group comparisons were performed by LSD. Results there were significant differences in DLP and Ed between the two groups. The Ed of group B was decreased by 40.33g than that of group A, there was no significant difference in CT value of hepatic parenchyma between group A and group A (P < 0.05). There were significant differences in CT value of liver parenchyma between group A and group A (P < 0.05). It was found that the CT value of liver in group B _ (1) B _ (5) was significantly different from that in group A (P < 0.05), but that in group B (group B _ (1) B _ (1) B _ (5) the CT value of liver parenchyma was higher than that in group A (P < 0.05). There was no significant difference in SD and SNR between group B 5 and group A. There were significant differences in SD and SNR between group B 5 and group A. There were significant differences in SD and SNR between group B 5 and other groups. There were significant differences in subjective scores of images (P < 0.05). The scores of vessel display and sclerosing artifact were higher than those of other groups (P < 0.05), but the scores of "wax" artifact were lower than those of other groups (P < 0.05). Conclusion the enhanced CT scan combined with SAFIRE-3 reconstruction technique can obtain good image quality and reduce the effective radiation dose.
【學位授予單位】：貴州醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R816.5

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