基于常壓低氧艙的人的低氧耐力調(diào)控與評價方法研究
發(fā)布時間:2018-06-02 08:11
本文選題:PD-模糊算法 + 機體最優(yōu)習(xí)服速率; 參考:《山東大學(xué)》2016年博士論文
【摘要】:我國國土面積的六分之一是由3000米以上的高山、高原構(gòu)成的。寒冷、風(fēng)大、空氣稀薄,氣候多變是高原的主要氣候特征?諝庀”,氧分壓低,是高原環(huán)境對機體影響的主要因素。頭痛、頭昏、失眠、乏力、四肢發(fā)麻、眼花、耳鳴是高原不適人群進入高原后的普遍反應(yīng),重的高原不適人群則可能發(fā)生胸悶、呼吸困難、惡心、嘔吐、浮腫等癥狀進而危及生命。隨著我國社會經(jīng)濟發(fā)展及國防戰(zhàn)略的需要,前往高原地區(qū)的人員越來越多。因此,如何保障上述人員的安全及提高高原居民的生活水平和健康質(zhì)量,一直是高原醫(yī)學(xué)研究的熱點之一。本文在俞夢孫院士高原健康相關(guān)理論的指導(dǎo)下開展相關(guān)工作。首先分析了模擬高原低氧環(huán)境常規(guī)裝備的特點及難點,本著控制誤差小、安全性、經(jīng)濟性及易于推廣的原則,在充分利用艙體漏氣性的基礎(chǔ)上結(jié)合PD-模糊控制算法研制了一種新型常壓低氧艙。然后在驗證間歇性低氧預(yù)習(xí)服是一種有效的提高人的低氧耐力的基礎(chǔ)上,進行了人體形成低氧適應(yīng)機制的低氧環(huán)境最優(yōu)變化率驗證試驗,并在人體對環(huán)境變化的自適應(yīng)功能特征與間歇性低氧訓(xùn)練方法結(jié)合的基礎(chǔ)上,提出漸進型間歇性低氧訓(xùn)練方案。接著,針對常規(guī)的人的低氧耐力評價手段單一、只注重低氧預(yù)習(xí)服前后對比分析,忽視低氧預(yù)習(xí)服訓(xùn)練過程的分析,提出了在常規(guī)評價方法的基礎(chǔ)上結(jié)合K均值聚類及多尺度熵分析的評價方法。最后,介紹了該成果已經(jīng)取得的軍事價值和民用領(lǐng)域推廣的可行性及相關(guān)理論成果。主要內(nèi)容包括:1、針對常壓低氧艙控制系統(tǒng)具有非線性、大慣性、純時滯以及對象模型不確定的難點,本文設(shè)計和研制了基于艙體的非密閉性的新型常壓低氧艙。該研究在精確測得艙體不密封性基礎(chǔ)上,利用氣體分子擴散原理,發(fā)展了基于PD-模糊控制算法的低氧氣體環(huán)境控制技術(shù)。結(jié)果表明,新型常壓低氧艙可模擬海拔高度0-6000m,氮氣利用率92%以上,誤差±35m,最大響應(yīng)時間2.52min,穩(wěn)定性97%以上,達到模擬高原低氧環(huán)境的要求。解決了常壓低氧艙控制精度不高、不易推廣的問題。2、設(shè)置8人的低氧預(yù)習(xí)服訓(xùn)練,驗證了間歇性低氧預(yù)習(xí)服,能夠改善海拔3600米時人的低氧耐力,是一種急進高原主動的快速適應(yīng)保障方案。通過血氧飽和度、心率、呼吸率、深睡時間、覺醒次數(shù)及中樞性呼吸暫停指數(shù)等指標(biāo)對人的低氧耐力進行多個方面的具體量化。3、針對漸進型間歇性低氧預(yù)習(xí)服,缺乏理論依據(jù)及習(xí)服目標(biāo)不明確等問題。為使低氧環(huán)境變化速率與人體自組織時間常數(shù)相匹配,從而達到"主動、快速適應(yīng)"的目的,進行了人體形成低氧適應(yīng)機制的低氧環(huán)境最優(yōu)變化率驗證試驗研究。結(jié)果表明,人體低氧適應(yīng)機制形成的最優(yōu)低氧環(huán)境變化速率存在被限定的動態(tài)范圍與我們要去的目的地海拔高度有關(guān),這為相關(guān)的漸進型間歇性低氧預(yù)習(xí)服,提供了理論依據(jù)。在此基礎(chǔ)上我們提出了 4500米以下的漸進型間歇性低氧預(yù)習(xí)服方案。4、針對人的低氧耐力評價方法單一,只注重低氧預(yù)習(xí)服結(jié)果,忽視低氧預(yù)習(xí)服過程的分析。本文結(jié)合漸進型低氧預(yù)習(xí)服方案,在常規(guī)的人的低氧耐力評價方法的基礎(chǔ)上,提出了K均值聚類及多尺度熵的人的低氧耐力評價方法。結(jié)果表明,K均值聚類是辨識機體低氧耐力一種更全面有效的方法,多尺度熵可以對漸進型低氧預(yù)習(xí)服的調(diào)節(jié)過程進行分析。在此過程中,發(fā)現(xiàn)機體具有低氧記憶性。機體在形成低氧環(huán)境的適應(yīng)機制后,即使返回平原地區(qū),低氧習(xí)服功能消退后,仍存在記憶性,一旦低氧環(huán)境再次出現(xiàn),會迅速喚醒機體已建立起來的低氧習(xí)服機制。5、介紹該成果已取得的軍事價值:該成果至今已經(jīng)在我軍7個部隊、180多名空勤以及2000余名地勤人員中得到了成功應(yīng)用,進行過低氧預(yù)習(xí)服訓(xùn)練的飛行人員均未見中重度高原反應(yīng)的發(fā)生,輕度反應(yīng)人員不足10%;分析該成果基于"援藏干部的低氧預(yù)習(xí)服研究"民用推廣的可行性;闡述基于人體多層次自組織功能認識高原反應(yīng)、間歇性低氧訓(xùn)練的自組織系統(tǒng)適應(yīng)環(huán)境能力模型、漸進型間歇性低氧訓(xùn)練(PIHE)、機體適應(yīng)低氧環(huán)境變化的速率VA的普遍意義及低氧適應(yīng)能力的消退性及其記憶性的相關(guān)理論研究。
[Abstract]:1/6 of China's land area is made up of high mountains and high altitude of more than 3000 meters. Cold, windy, thin air and changeable climate are the main climatic characteristics of the plateau. The air is thin and oxygen is low, it is the main factor affecting the body. Headache, dizziness, insomnia, fatigue, numbness in the limbs, eye flowers and tinnitus are inaccessible to the plateau. The general response to the plateau, the heavy plateaus group may suffer from symptoms such as chest tightness, dyspnea, nausea, vomiting and swelling. With the social and economic development of our country and the need of national defense strategy, there are more and more people to the plateau. Therefore, how to safeguard the safety of the above personnel and improve the living of the plateau residents The living level and health quality have always been one of the hot spots in the research of plateau medicine. This paper has carried out some relevant work under the guidance of the plateau health related theory of academician Yu Mengsun. Firstly, the characteristics and difficulties of the conventional equipment in simulated plateau hypoxia environment are analyzed, and the principles of small control error, safety, economy and easy popularization are used in full use. On the basis of the air leakage of the cabin, a new type of atmospheric hypooxygen cabin is developed with the PD- fuzzy control algorithm. Then, it is proved that intermittent hypoxic preview is an effective way to improve human hypoxia tolerance. Based on the combination of adaptive functional characteristics and intermittent hypoxia training, a progressive intermittent hypoxia training scheme is proposed. Then, the conventional methods of evaluating low oxygen endurance are only single, focusing on contrast analysis before and after hypoxic preview, ignoring the analysis of training course for hypoxic preconditioning, and putting forward the basis of the conventional evaluation method. The evaluation method is combined with K mean clustering and multi-scale entropy analysis. Finally, the military value and the feasibility of popularizing the civil field and the related theoretical results have been introduced. The main contents are as follows: 1, the difficulties of nonlinear, large inertia, pure time delay and the uncertainty of the object model for the control system of the atmospheric oxygen cabin are discussed. A new type of normal pressure hypoxic cabin based on the non hermetic cabin is designed and developed. On the basis of accurately measuring the non sealing property of the hatch, the low oxygen gas environment control technology based on the PD- fuzzy control algorithm is developed by using the principle of gas molecular diffusion. The result shows that the new atmospheric oxygen tank can simulate the altitude of 0-6000m, and the nitrogen use is used. The rate is above 92%, the error is + 35m, the maximum response time is 2.52min, the stability is more than 97%, which can reach the requirement of simulated plateau hypoxia environment. It solves the problem.2 that the control precision is not high in the normal pressure hypoxic chamber and is not easy to popularize. It sets up 8 people's hypoxic prehabit training, verifies the intermittent hypoxic prehabit, and can improve the low oxygen endurance of people at 3600 meters altitude. It is a The rapid adaptation support scheme for the rapid development of high altitude plateau. Through the indexes of blood oxygen saturation, heart rate, respiratory rate, deep sleep time, awakening times and central apnea index, the human hypoxic endurance is quantified by.3. In order to match the change rate of hypoxic environment with the time constant of human self tissue, to achieve the goal of "active and rapid adaptation", the test study on the optimal rate of change of low oxygen environment for the formation of hypoxic adaptation mechanism in human body has been carried out. The results show that the optimal hypoxia environment change rate of the adaptive mechanism of human hypoxia is limited. The dynamic range is related to the altitude of the destination we are going to. This provides a theoretical basis for the related progressive intermittent hypoxia preview. On this basis, we propose a progressive intermittent hypoxic preview scheme.4 under 4500 meters. The method of evaluating human hypoxia tolerance is single, focusing only on the results of hypoxic Preview and neglecting the results of hypoxic preview. The analysis of the process of hypoxic preview. Based on the progressive hypoxic preview scheme, based on the conventional methods of evaluating low oxygen endurance, the K mean clustering and multi-scale entropy of human hypoxia tolerance evaluation method is proposed. The results show that K mean clustering is a more comprehensive and effective method to identify the low oxygen endurance of the body, and the multiscale entropy can be used. In this process, the adjustment process of the progressive hypoxic preview is analyzed. In this process, it is found that the body has the memory of hypoxia. After the adaptation mechanism of the hypoxic environment is formed, the body still has memory after the return of the hypoxia acclimatization function even to the plain area. Once the hypoxia environment appears again, it will quickly wake up the lower body. The oxygen acclimation mechanism,.5, introduces the military value of the results: the results have been successfully applied to 7 troops, more than 180 aircrew and more than 2000 ground crew members. All pilots who have been trained in hypoxic preconditioning have not seen the occurrence of moderate to severe plateau reactions and less than 10% of the mild reaction personnel. The feasibility of the civil popularization of "hypoxic preview study" for "Tibetan cadres", the general significance of the adaptive low oxygen training (PIHE), the change rate of the hypoxic environment of the body and the adaptation to the hypoxic environment, and the adaptation to the hypoxia adaptation, based on the multi-level self-organizing function of the human body to recognize the plateau response, the self-organizing system of intermittent hypoxia training, the gradual intermittent hypoxia training (PIHE), and the adaptation to the hypoxic environment. The regression theory of ability and its memory.
【學(xué)位授予單位】:山東大學(xué)
【學(xué)位級別】:博士
【學(xué)位授予年份】:2016
【分類號】:R85
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