發(fā)布時(shí)間：2018-05-23 19:21

  本文選題：肺腫瘤 + 雙能量成像　； 參考：《臨床放射學(xué)雜志》2015年08期

【摘要】：目的探討雙源CT(DSCT)雙能量成像技術(shù)在孤立性肺腫塊診斷中的價(jià)值。方法對67例肺內(nèi)孤立性腫塊(惡性腫瘤48例,良性腫塊19例)行DSCT常規(guī)增強(qiáng)及雙能增強(qiáng)掃描,獲得腫塊動(dòng)、靜脈期常規(guī)增強(qiáng)與虛擬平掃及碘基圖CT值、40~190 keV系列單能量圖像CT值,并記錄各腫塊動(dòng)、靜脈期碘含量,計(jì)算動(dòng)、靜脈腫塊能譜曲線斜率。利用F檢驗(yàn)、t檢驗(yàn)或ROC曲線對比分析能譜曲線、碘含量及碘基圖CT值。結(jié)果動(dòng)脈期腫塊增強(qiáng)CT值與碘基圖CT值差異無統(tǒng)計(jì)學(xué)意義(P0.05),動(dòng)脈期增強(qiáng)圖像與碘基圖CT值顯示高度一致性,相關(guān)系數(shù)r=0.89;靜脈期腫塊增強(qiáng)CT值與碘基圖CT值差異有統(tǒng)計(jì)學(xué)意義(P0.05)。動(dòng)脈期在40~100 keV區(qū)間下肺惡性腫瘤、炎性腫塊及結(jié)核瘤的CT值兩兩之間差異均有統(tǒng)計(jì)學(xué)意義(P0.05);靜脈期在40~110 keV下肺惡性腫瘤、炎性腫塊及結(jié)核瘤的CT值兩兩之間差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。以CT值18 HU作為腫塊良惡性診斷閾值(18 HU為良性,≥18 HU為惡性),碘基圖CT值診斷孤立性肺腫塊良惡性的敏感性為83.3%,特異性為76.2%,準(zhǔn)確性為81.2%。動(dòng)、靜脈期惡性腫瘤、炎性腫塊及結(jié)核球的碘含量均值分別為(1.00±0.07)mg/ml、(1.92±0.12)mg/ml、(0.46±0.05)mg/ml和(1.25±0.14)mg/ml、(2.06±0.18)mg/ml及(0.58±0.06)mg/ml;能譜曲線斜率均值分別為-0.96、-1.38、-1.97和-2.27、-0.45、-0.56,兩期惡性腫瘤與炎性腫塊、炎性腫塊與結(jié)核球、惡性腫瘤與結(jié)核球間碘含量及能譜曲線斜率差異均有統(tǒng)計(jì)學(xué)意義(P均0.05)。結(jié)論采用DSCT雙能量成像的參數(shù)進(jìn)行定量分析,對孤立性肺腫塊的良惡性鑒別診斷有較大價(jià)值。
[Abstract]:Objective to evaluate the diagnostic value of dual source CT DSCT imaging in solitary pulmonary masses. Methods 67 cases of solitary pulmonary mass (malignant tumor 48 cases, benign tumor 19 cases) were examined by conventional and dual enhanced DSCT. The conventional contrast enhancement, virtual plain scan and CT value of 40 ~ 190 keV series of single energy images were obtained in arteriovenous phase. The iodine content of each tumor was recorded and the slope of energy spectrum curve was calculated. Energy spectrum curve, iodine content and CT value of iodine base map were analyzed by F test or ROC curve. Results there was no significant difference between the enhancement CT value of arterial mass and the CT value of iodide radiography (P 0.05). The CT value of arterial phase enhancement was highly consistent with the CT value of iodide base image, the correlation coefficient was 0.89, and the CT value of venous mass was significantly different from that of iodide base image (P 0.05). The CT values of pulmonary malignant tumors, inflammatory masses and tuberculoma in arterial phase were significantly different between 40 ~ 100 keV and 40 ~ 110 keV, respectively. The CT values of inflammatory masses and tuberculoma were significantly different (P 0.05). Using 18 Hu as the diagnostic threshold for benign and malignant tumors and 鈮，

本文編號：1926020