發(fā)布時間：2018-05-07 13:02

  本文選題：肝臟占位 + 血流灌注��； 參考：《中國醫(yī)學(xué)計算機成像雜志》2015年04期

【摘要】：目的:探討多b值DWI在肝臟常見占位性病變鑒別診斷中的應(yīng)用價值。方法:選取經(jīng)臨床證實肝臟占位性病變48例62個病灶行多b值的DWI掃描,分別擬合出10個b值A(chǔ)DC_(10b)圖,3個低b值(0s/mm~2、50s/mm~2、100s/mm~2)ADClow圖,3個高b值(500s/mm~2、750s/mm~2、1000s/mm~2)ADC_(high)圖,并將ADC_(low)與ADC_(high)值之間的差異定義為ADC_(perf)值。在病變中央?yún)^(qū)及邊緣區(qū)繪制兩個相同大小的ROI(region of interest),分別計算ADC_(low)、ADC_(high)、ADC_(perf)、ADC_(3b)及ADC_(10b)值,分析肝臟良惡性占位及病變中央?yún)^(qū)及邊緣區(qū)各ADC值之間的差異。結(jié)果:良惡性占位之間其中央?yún)^(qū)和邊緣區(qū)在灌注(ADC_(perf))圖上ADC值的差異均有統(tǒng)計學(xué)意義(P0.05),病變中央?yún)^(qū)及邊緣區(qū)之間良惡性占位在ADC_(perf)圖上ADC值的差異有統(tǒng)計學(xué)意義(P0.05);除了在ADC_(low)外,其余ADC_(10b),ADC_(high),ADC_(3b)圖上良惡性占位之間中央?yún)^(qū)及邊緣區(qū)ADC值的差異均有統(tǒng)計學(xué)意義(P0.05),惡性腫瘤中央?yún)^(qū)與邊緣區(qū)ADC值的差異均有統(tǒng)計學(xué)意義(P0.05)。而良性占位中央?yún)^(qū)及邊緣區(qū)ADC值差異,除了在ADC_(low)外,均無統(tǒng)計學(xué)意義(P0.05)。結(jié)論:多b值DWI技術(shù)可提供肝臟占位血流灌注特點的參考信息,與其他MRI成像序列相結(jié)合,能夠提高肝臟占位性病變的診斷及鑒別診斷準確率。
[Abstract]:Objective: to evaluate the value of multi-b-value DWI in differential diagnosis of common occupying lesions of liver. Methods: a total of 62 lesions of 48 patients with clinically proven hepatic occupying lesions were examined with DWI with multiple b values, and 10 b-value ADCC / 10 b maps were fitted respectively, 3 low b values (250s / mm ~ 250s / mm ~ 2100s / mm / mm ~ 2DDC low map) and 3 high b ~ (b) values of 500s / s / mm ~ 2750s / mm / s ~ 2 ~ 10s / s / 2d / d ~ 2d / d were fitted, respectively, and the difference between the values of ADCP) and ADCS / T was defined as the value of ADCP / D). Two ROI(region of the same size were drawn in the central and marginal areas of the lesion, and the ADC values of the central and marginal areas of the lesion were calculated, respectively, and the differences between the ADC values of the benign and malignant liver and the central and marginal areas of the lesion were analyzed. Results: there were significant differences in ADC values between the central and marginal regions of benign and malignant lesions on the perfusion map (P 0.05). The difference of ADC between the central and marginal regions of benign and malignant lesions was statistically significant (P 0.05). The ADC values of central and marginal areas in benign and malignant areas were significantly different between benign and malignant lesions, and the ADC values in central and marginal areas of malignant tumors were significantly different from those in central and marginal areas of malignant tumors. However, there was no significant difference in ADC between the central and marginal areas of benign occupation except in ADC. Conclusion: Multi-b-value DWI technique can provide reference information for the characteristics of hepatic space-occupying blood flow perfusion and can be combined with other MRI imaging sequences to improve the accuracy of diagnosis and differential diagnosis of hepatic space-occupying lesions.
【作者單位】： 新疆醫(yī)科大學(xué)第一附屬醫(yī)院影像中心;新疆醫(yī)科大學(xué)第一附屬醫(yī)院病理科;新疆醫(yī)科大學(xué)第二附屬醫(yī)院影像中心;
【基金】：國家自然科學(xué)基金No.81360214~~
【分類號】：R575;R816.5

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