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擺位誤差對乳腺癌患者放療中心臟受量的影響

發(fā)布時間:2018-05-03 07:19

  本文選題:乳腺癌 + 放療 ; 參考:《廣西醫(yī)學(xué)》2016年12期


【摘要】:目的探討擺位誤差對乳腺癌患者放療中心臟受量的影響。方法選取18例乳腺癌放療患者制定放療計劃,保持原計劃射野角度、射野劑量、射野權(quán)重等參數(shù)不變,移動射野中心,模擬3個方向(X、Y、Z軸)的線性擺位誤差,重新計算移動射野中心后的心臟受量,并與原計劃比較。其中X-、Y-分別代表患者身體相對于射野向患側(cè)、頭側(cè)移動。結(jié)果新計劃X-3、X-5、X-7、X-9、Y-5、Y-7、Y-9的30 Gy劑量線所包繞心臟的體積百分比(V30)較原計劃增加(P0.05),其中X-7、X-9、Y-9超過限量;X-9、Y-7、Y-9、Z7、Z9的V40較原計劃增加(P0.05);X-5、X-7、X-9、Y-5、Y-7、Y-9的心臟平均劑量較原計劃增加(P0.05),增加幅度分別為54 c Gy、80 c Gy、110 Gy、100 c Gy、142 c Gy、182 c Gy。結(jié)論對于接受放療的乳腺癌患者,患側(cè)方向和頭方向均≥5 mm的擺位誤差會使心臟平均劑量明顯增加;患側(cè)方向≥3 mm、頭方向≥5 mm的擺位誤差會使心臟V30明顯增加。建議當(dāng)患側(cè)方向、頭方向的擺位誤差≥5 mm時,應(yīng)校正誤差。
[Abstract]:Objective to investigate the effect of pendulum error on cardiac dose in patients with breast cancer. Methods 18 patients with breast cancer were selected to make the radiotherapy plan. The parameters such as the original field angle, the dose and the weight of the field were kept constant, the center of the field was moved, and the error of linear pendulum was simulated in 3 directions. Recalculate cardiac recipient after moving field center and compare with original plan. X-ray-Y-represents the patient's body relative to the field to the affected side, head-side movement. Results compared with the original plan, the volume percentage of the heart encased by the 30 Gy dose line of the new plan X-3X, X-5, X-5, X-7, Y-7, and Y-9, was higher than that of the original plan, and the V40 of the X-7X X-9 Y-9 was higher than that of the original plan, which was 54% higher than that of the original plan, and the average cardiac dose of the new plan was 54% higher than that of the original plan. C Gy,80 c Gy,110 Gy,100 c Gy,142 c Gy,182 c Gy. Conclusion for breast cancer patients receiving radiotherapy, the mean cardiac dose will be significantly increased by the error of the direction of the affected side and the direction of the head 鈮,

本文編號:1837535

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