本文選題：甲狀腺結(jié)節(jié)　切入點(diǎn)：體層攝影術(shù)　出處：《廣西醫(yī)科大學(xué)》2017年碩士論文

【摘要】：研究目的:分析甲狀腺良、惡性結(jié)節(jié)的CT征象,探索CT在甲狀腺良、惡性結(jié)節(jié)的鑒別診斷的應(yīng)用價(jià)值。研究方法:回顧性分析150例甲狀腺結(jié)節(jié)的CT表現(xiàn)及患者一般情況,包括邊界、包膜、鈣化、囊變、強(qiáng)化程度、淋巴結(jié)腫大、年齡、性別、橫斷面前后徑與橫徑的比值(A/T)等,與病理結(jié)果進(jìn)行對比,比較良、惡性結(jié)節(jié)間的差異性,及與甲狀腺癌發(fā)生有關(guān)的因素進(jìn)行l(wèi)ogistic回歸分析。研究結(jié)果:在年齡、A/T比值、結(jié)節(jié)的數(shù)量、邊界、包膜、囊變及淋巴結(jié)腫大等方面,良、惡性結(jié)節(jié)的差異有統(tǒng)計(jì)學(xué)意義(P0.05)。無包膜和邊界不清對于診斷甲狀腺惡性結(jié)節(jié)的靈敏度和特異度分別為96.9%、76.9%和62.4%、51.8%,陽性預(yù)測值和陰性預(yù)測值分別為66.3%、54.9%和96.4%、74.6%。在平掃及增強(qiáng)各期中,良、惡性及正常甲狀腺結(jié)節(jié)CT值的差別有統(tǒng)計(jì)學(xué)意義(P0.05)。Logistic多因素回歸分析表明無包膜,淋巴結(jié)腫大及A/T比值增大與甲狀腺癌的發(fā)生獨(dú)立相關(guān)。研究結(jié)論:CT掃描對于甲狀腺良、惡性結(jié)節(jié)的鑒別診斷有一定價(jià)值及可行性。年齡、A/T比值、病灶數(shù)量、邊緣、包膜、囊變及淋巴結(jié)腫大因素在不同性質(zhì)結(jié)節(jié)中存在差異,無包膜、邊界不清、無囊變、淋巴結(jié)腫大及單發(fā)病灶等征象提示惡性可能性大。
[Abstract]:Objective: to analyze the CT features of benign and malignant thyroid nodules and to explore the value of CT in the differential diagnosis of benign and malignant thyroid nodules. These include boundary, capsule, calcification, cystic degeneration, degree of enhancement, enlarged lymph nodes, age, sex, ratio of anterior and posterior diameter of cross section to transverse diameter (A / T) and so on. The difference between benign and malignant nodules was compared with pathological results. Logistic regression analysis was used to analyze the factors related to thyroid carcinogenesis. The results showed that the age ratio of A / T, the number of nodules, the number of nodules, the capsule, cysts and lymphadenopathy were good. The sensitivity and specificity for the diagnosis of malignant thyroid nodule were 96.999% and 62.4%, respectively. The positive predictive value and negative predictive value were 66.3% and 96.44.6.The positive predictive value and negative predictive value were 66.3% and 96.44.60.The sensitivity and specificity for the diagnosis of malignant thyroid nodule were 96.9% and 62.4%, respectively. The positive predictive value and negative predictive value were 54.9% and 96.44.6.The positive predictive value and negative predictive value were 66.3% and 96.44.6.The positive predictive value and negative predictive value were 66.3% and 96.4%, respectively. The difference of CT value between malignant and normal thyroid nodules was statistically significant (P 0.05). Logistic multivariate regression analysis showed that there was no capsule, lymph node enlargement and the increase of A / T ratio were independent of the occurrence of thyroid carcinoma. The differential diagnosis of malignant nodules has certain value and feasibility. There are differences in the factors of age, A / T ratio, number of lesions, margin, capsule, cystic and lymphadenopathy in different types of nodules, no capsule, unclear boundary, no cystic change. Signs of lymphadenopathy and single lesions suggest that malignancy is more likely.
【學(xué)位授予單位】：廣西醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R736.1;R730.44;R581

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