CT和MRI圖像配準融合聯(lián)合3D打印技術(shù)在難治性骨盆腫瘤術(shù)前規(guī)劃中的應(yīng)用
發(fā)布時間:2018-03-29 02:33
本文選題:磁共振成像 切入點:圖像配準 出處:《上海交通大學(xué)學(xué)報(醫(yī)學(xué)版)》2017年09期
【摘要】:目的·探討CT、MRI圖像配準融合聯(lián)合3D打印技術(shù),在輔助難治性骨盆腫瘤術(shù)前規(guī)劃中的應(yīng)用價值。方法·回顧性總結(jié)2014年3月至2016年12月于上海交通大學(xué)醫(yī)學(xué)院附屬第九人民醫(yī)院接受治療的難治性骨盆腫瘤病例,術(shù)前常規(guī)行薄層CT、MRI檢查,借助Medraw軟件實現(xiàn)CT、MRI圖像快速配準融合,精確判定腫瘤安全邊界,輔助設(shè)計并3D打印個體骨盆腫瘤模型、假體和(或)導(dǎo)板。結(jié)果·共納入難治性骨盆腫瘤患者13例(軟骨肉瘤8例、骨肉瘤合并動脈瘤樣骨囊腫1例、未分化性肉瘤1例、纖維結(jié)締組織增生性纖維瘤1例、孤立性纖維瘤/血管外皮瘤1例、轉(zhuǎn)移性鱗癌1例),平均年齡(50.0±8.5)歲。基于Enneking分區(qū):Ⅰ區(qū)2例、Ⅰ+Ⅱ區(qū)2例、Ⅱ+Ⅲ區(qū)1例、Ⅰ+Ⅱ+Ⅲ區(qū)3例、Ⅰ+Ⅱ+Ⅳ區(qū)1例、Ⅰ+Ⅱ+Ⅲ+Ⅳ區(qū)1例、Ⅰ+Ⅳ區(qū)1例、Ⅱ+Ⅳ區(qū)1例、Ⅳ區(qū)1例。腫瘤最大直徑平均值(15.15±4.81)cm,均未累及盆腔大血管。結(jié)合術(shù)中腫瘤邊界快速冰凍結(jié)果及假體安裝情況,判斷基于融合圖像的術(shù)前評估、規(guī)劃的虛擬手術(shù)方案與手術(shù)的實施一致。結(jié)論·薄層CT、MRI圖像配準融合聯(lián)合3D打印技術(shù),可以精確判定難治性骨盆腫瘤邊界,輔助臨床設(shè)計個體化3D打印假體和導(dǎo)板,在難治性骨盆腫瘤術(shù)前規(guī)劃中具有重要的臨床應(yīng)用價值。
[Abstract]:Objective to explore the technique of CT MRI image registration and fusion combined with 3D printing. Methods from March 2014 to December 2016, patients with refractory pelvic tumors received treatment at the Ninth people's Hospital affiliated to Shanghai Jiaotong University School of Medicine. TLC MRI was performed before operation, and Medraw software was used to realize fast registration and fusion of CT MRI images, to accurately determine the safety boundary of tumors, and to design and 3D print individual pelvic tumor models. Results 13 patients with refractory pelvic tumors (8 chondrosarcoma, 1 osteosarcoma with aneurysm cyst, 1 undifferentiated sarcoma, 1 fibrous connective tissue proliferative fibroma) were included. One case of solitary fibroma / hemangiopericytoma and one case of metastatic squamous cell carcinoma (mean age: 50.0 鹵8.5) years. Based on Enneking, there were 2 cases in zone 鈪,
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