本文選題：甲狀腺腫瘤　切入點：甲狀腺切除術　出處：《中國醫(yī)學影像學雜志》2017年06期 　論文類型：期刊論文

【摘要】：目的探討分化型甲狀腺癌(DTC)術后刺激性甲狀腺球蛋白(ps-Tg)水平在~(131)I治療前預測患者功能性轉移灶的價值,用于指導~(131)I治療。資料與方法回顧性分析101例在連云港市第一人民醫(yī)院行甲狀腺全切術及頸淋巴結清掃術的DTC患者,~(131)I治療前1 d測ps-Tg水平,~(131)I治療后5~7 d進行~(131)I-SPECT/CT顯像。根據~(131)I-SPECT/CT顯像判定是否存在功能性轉移灶,分為無轉移組(M0)和轉移組(M1),并通過ROC曲線評估ps-Tg水平預測功能性轉移的價值。結果 M1組的ps-Tg水平高于M0組,差異有統(tǒng)計學意義(U=328.00,P0.001),ps-Tg值的ROC曲線下面積為0.870,診斷界值為40.60 ng/ml,敏感度、特異度、準確度分別為72.34%、100.00%、87.13%。結論 ps-Tg水平可作為預測功能性轉移的有效指標,可指導~(131)I治療。
[Abstract]:Objective to investigate the value of the level of stimulating thyroid globulin (s-Tg) in predicting functional metastases in patients with differentiated thyroid carcinoma (DTC) before treatment. Materials and methods 101 patients with DTC undergoing total thyroidectomy and neck lymph node dissection in Lianyungang first people's Hospital were analyzed retrospectively. The level of ps-Tg was measured 1 day before and 57 days after treatment. According to the I-SPECT / CT imaging, we can determine whether there are functional metastases, ROC curve was used to evaluate the value of ps-Tg level in predicting functional metastasis. Results the ps-Tg level in M1 group was higher than that in M0 group. The area under the ROC curve was 0.870, the diagnostic threshold value was 40.60 ng / ml, the sensitivity, specificity and accuracy were 72.340.00% and 87.130.Conclusion the level of ps-Tg can be used as an effective index for predicting functional metastasis and can be used to guide the treatment of PS-Tg.
【作者單位】： 徐州醫(yī)科大學附屬連云港醫(yī)院 連云港第一人民醫(yī)院核醫(yī)學科;
【基金】：連云港市衛(wèi)生計生科技項目(201610)
【分類號】：R445.1;R730.44;R736.1
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本文編號：1581412