職業(yè)性汞中毒患者心身癥狀的調(diào)查研究
發(fā)布時(shí)間：2018-08-09 14:39
【摘要】：研究目的 我國(guó)作為制造業(yè)大國(guó),近年來(lái),伴隨著社會(huì)經(jīng)濟(jì)迅速發(fā)展,但由于經(jīng)濟(jì)水平的限制,鄉(xiāng)鎮(zhèn)、個(gè)私企業(yè)的興起,新工種、新行業(yè)、新毒物的出現(xiàn),以及職業(yè)性有害因素的轉(zhuǎn)嫁等問(wèn)題的存在,職業(yè)衛(wèi)生仍不容忽視。本文通過(guò)對(duì)職業(yè)性汞中毒患者心身癥狀的調(diào)查研究,認(rèn)識(shí)生產(chǎn)過(guò)程中存在的職業(yè)性有害因素對(duì)勞動(dòng)者健康的不良影響,為今后綜合治療職業(yè)中毒患者,提高療效,提供相關(guān)參考。 資料來(lái)源與方法 以符合中華人民共和國(guó)衛(wèi)生部頒發(fā)的職業(yè)性汞中毒診斷標(biāo)準(zhǔn)(GBZ89-2007診斷標(biāo)準(zhǔn)的職業(yè)性汞中毒患者作為研究對(duì)象,同期企業(yè)健康體檢的志愿者為對(duì)照組。采用問(wèn)卷調(diào)查方法,調(diào)查患者心理癥狀(癥狀自評(píng)量表SCL90)、睡眠質(zhì)量(Pittsburgh睡眠質(zhì)量指數(shù)量表PSQI)、焦慮積分(焦慮自評(píng)量表SAS)和抑郁積分(抑郁自評(píng)量表SDS)。比較分析兩組的睡眠情況和焦慮抑郁情況；根據(jù)SAS、 SDS積分對(duì)職業(yè)性汞中毒組分組,并相互比較以及與對(duì)照組比較,分析各組的睡眠情況。 統(tǒng)計(jì)學(xué)分析 用SPSS13.0軟件進(jìn)行數(shù)據(jù)處理,實(shí)驗(yàn)所得數(shù)據(jù)以平均值土標(biāo)準(zhǔn)差表示,采用Fisher精確概率法及獨(dú)立樣本T檢驗(yàn)對(duì)數(shù)據(jù)進(jìn)行分析,P0.05時(shí),認(rèn)為有統(tǒng)計(jì)學(xué)意義。 結(jié)果： 1、一般資料：實(shí)驗(yàn)組,共145例,男63例,女82例,年齡22±52.58歲,工齡2.0+1.54年；對(duì)照組,59例,男28例,女31例,年齡234±2.35歲,工齡2.34±1.9年。 2、職業(yè)性汞中毒患者心理健康狀況評(píng)價(jià)：實(shí)驗(yàn)組患者的軀體化、抑郁、焦慮、恐懼癥狀與對(duì)照組比較差異有顯著性意義(p0.05),提示實(shí)驗(yàn)組伴有心理軀體癥狀。 3、職業(yè)性汞中毒患者焦慮抑郁評(píng)價(jià)：實(shí)驗(yàn)組SAS粗分29.43士15.24,SAS40分陽(yáng)性率12.41%(18/145例),同比對(duì)照組SAS粗分26.10土11.55,SAS40分陽(yáng)性率3.39%(2/59例)差異均有顯著性意義(p0.05)。實(shí)驗(yàn)組SDS粗分31.29士13.32,同比對(duì)照組SDS粗分26.51士13.91差異有顯著性意義(p0.05),實(shí)驗(yàn)組SDS40分陽(yáng)性率3.39%(10/145例),同比對(duì)照組SDS40分陽(yáng)性率56.90%(4/59例),差異無(wú)顯著性意義(P0.05)。表明職業(yè)性汞中毒患者存在情緒障礙,且焦慮情緒更為突出。 4、職業(yè)性汞中毒患者的睡眠情況：實(shí)驗(yàn)組在睡眠質(zhì)量、睡眠障礙和日間功能障礙3個(gè)因子以及PsQI,總分與對(duì)照組比較差異有顯著性意義(p0.05),而入睡時(shí)間、睡眠時(shí)間、睡眠效率和催眠藥物4個(gè)因子與對(duì)照組比較差異無(wú)顯著性意義(p0.05)。表明職業(yè)性汞中毒患者較對(duì)照組存在部分因子的睡眠異常。 5、焦慮抑郁狀態(tài)對(duì)職業(yè)性汞中毒患者睡眠影響分析：125例無(wú)焦慮抑郁的職業(yè)性汞中毒患者與對(duì)照組比較在睡眠質(zhì)量、睡眠障礙、日間功能障礙3個(gè)因子和PSQI,總分有差異(p0.05),而入睡時(shí)間、睡眠時(shí)間、睡眠效率、催眠藥物4個(gè)因子與對(duì)照組比較無(wú)差異(p0.05)。20例伴焦慮抑郁的職業(yè)性汞中毒患者與對(duì)照組比較,在睡眠質(zhì)量、入睡時(shí)間、睡眠效率、睡眠障礙、睡眠時(shí)間、日間功能障礙6個(gè)因子和PSQI,總分有差異(p0.05)。只有催眠藥物無(wú)差異(p0.05)。伴焦慮抑郁的職業(yè)性汞中毒患者與無(wú)焦慮抑郁的職業(yè)性汞中毒患者比較睡眠質(zhì)量、入睡時(shí)間、睡眠時(shí)間、睡眠效率、睡眠障礙、日間功能障礙、催眠藥物所有7個(gè)因子和PSQI,總分,均有差異(p0.05)。 結(jié)論： 1.職業(yè)性汞中毒患者存在焦慮抑郁等情緒障礙。 2.職業(yè)性汞中毒患者存在睡眠異常,主要表現(xiàn)在睡眠質(zhì)量、睡眠障礙、日間功能障礙3個(gè)因子和PSQI.總分異常。 3.焦慮抑郁情緒障礙會(huì)加重職業(yè)性汞中毒患者的睡眠異常。
[Abstract]:research objective
As a big manufacturing country, in recent years, with the rapid development of social and economic development, the occupational health students can not be ignored because of the limitation of the economic level, the rise of township and township enterprises, the emergence of new industry, new industry, new poison, and the transfer of occupational harmful factors. The investigation of the symptoms to understand the adverse effects of occupational harmful factors on the health of the workers in the process of production, and to provide some reference for the future comprehensive treatment of occupational poisoning patients and the improvement of the curative effect.
Sources and methods of data
In accordance with the occupational mercury poisoning diagnostic criteria of occupational mercury poisoning (GBZ89-2007 diagnostic criteria) issued by the Ministry of health of the People's Republic of China as the research object, the volunteers of the medical examination in the same period were used as the control group. The psychological symptoms (symptom checklist SCL90) and sleep quality (Pittsburgh sleep) were investigated by questionnaire. Sleep quality index (PSQI), anxiety score (anxiety scale SAS) and depression score (SDS). The sleep conditions and anxiety and depression of the two groups were compared and analyzed. According to SAS, SDS scores were divided into groups of occupational mercury poisoning groups, and compared with the control group, the sleep conditions of each group were analyzed.
Statistical analysis
SPSS13.0 software is used for data processing. The experimental data are expressed with average soil standard deviation. The data are analyzed by Fisher precision probability method and independent sample T test. P0.05 is considered to have statistical significance.
Result:
1, general data: the experimental group, a total of 145 cases, 63 men, 82 women, age 22 + 52.58 years old, 2.0+1.54 years, the control group, 59 cases, 28 men, 31 cases, age 234 + 2.35 years, age 2.34 + 1.9 years.
2, evaluation of mental health status of patients with occupational mercury poisoning: the differences of somatization, depression, anxiety and fear in the experimental group were significantly different from those in the control group (P0.05), suggesting that the experimental group was accompanied by psychosomatic symptoms.
3, the evaluation of anxiety and depression in patients with occupational mercury poisoning: the SAS crude score of the experimental group was 29.43 and 15.24, the positive rate of SAS40 was 12.41% (18/145 cases), the SAS crude score of the control group was 26.10 soil 11.55, the difference of SAS40 positive rate 3.39% (2/59 cases) was significant (P0.05). The experimental group SDS crude score was 31.29 13.32, and the difference of SDS coarse 26.51 of the control group was significantly different from the same period of the same period. The positive rate of SDS40 in the experimental group (P0.05) was 3.39% (10/145 cases), and the positive rate of SDS40 in the control group was 56.90% (4/59 case), the difference was not significant (P0.05). It showed that the occupational mercury poisoning patients had emotional disorder and the anxiety was more prominent.
4, the sleep condition of the patients with occupational mercury poisoning: the 3 factors of sleep quality, sleep disorder and daytime dysfunction and the total score of PsQI in the experimental group were significantly different from those in the control group (P0.05), but there was no significant difference between 4 factors of sleep time, sleep time, sleep efficiency and hypnotic drugs (P0.05). The patients with occupational mercury poisoning had abnormal sleep with some factors compared with the control group.
5, analysis of the effects of anxiety and depression on the sleep of patients with occupational mercury poisoning: 125 patients with occupational mercury poisoning without anxiety and depression were compared with the control group in sleep quality, sleep disorder, day dysfunction 3 factors and PSQI, total score difference (P0.05), while sleep time, sleep time, sleep efficiency, hypnotic drug 4 factors and control groups Compared with the control group, there were 6 factors in sleep quality, sleep time, sleep efficiency, sleep disorder, sleep time, and PSQI, and the total scores were different (P0.05) in sleep quality, sleep time, sleep time, and PSQI (P0.05). There was no difference in hypnotics (P0.05). Patients with occupational mercury poisoning associated with anxiety and depression were no more than those in the control group. Anxiety and depression of occupational mercury poisoning patients compared sleep quality, sleep time, sleep time, sleep efficiency, sleep disorders, daytime dysfunction, hypnotic drugs all 7 factors and PSQI, total score, there are differences (P0.05).
Conclusion:
1. Occupational mercury poisoning patients have emotional disorders such as anxiety and depression.
2. Occupational mercury poisoning patients have abnormal sleep, mainly manifested in sleep quality, sleep disorders, day dysfunction three factors and PSQI. total score abnormalities.
3. Anxiety and depression may aggravate the sleep disorder of occupational mercury poisoning patients.
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R135
本文編號(hào)：2174398
[Abstract]:research objective
As a big manufacturing country, in recent years, with the rapid development of social and economic development, the occupational health students can not be ignored because of the limitation of the economic level, the rise of township and township enterprises, the emergence of new industry, new industry, new poison, and the transfer of occupational harmful factors. The investigation of the symptoms to understand the adverse effects of occupational harmful factors on the health of the workers in the process of production, and to provide some reference for the future comprehensive treatment of occupational poisoning patients and the improvement of the curative effect.
Sources and methods of data
In accordance with the occupational mercury poisoning diagnostic criteria of occupational mercury poisoning (GBZ89-2007 diagnostic criteria) issued by the Ministry of health of the People's Republic of China as the research object, the volunteers of the medical examination in the same period were used as the control group. The psychological symptoms (symptom checklist SCL90) and sleep quality (Pittsburgh sleep) were investigated by questionnaire. Sleep quality index (PSQI), anxiety score (anxiety scale SAS) and depression score (SDS). The sleep conditions and anxiety and depression of the two groups were compared and analyzed. According to SAS, SDS scores were divided into groups of occupational mercury poisoning groups, and compared with the control group, the sleep conditions of each group were analyzed.
Statistical analysis
SPSS13.0 software is used for data processing. The experimental data are expressed with average soil standard deviation. The data are analyzed by Fisher precision probability method and independent sample T test. P0.05 is considered to have statistical significance.
Result:
1, general data: the experimental group, a total of 145 cases, 63 men, 82 women, age 22 + 52.58 years old, 2.0+1.54 years, the control group, 59 cases, 28 men, 31 cases, age 234 + 2.35 years, age 2.34 + 1.9 years.
2, evaluation of mental health status of patients with occupational mercury poisoning: the differences of somatization, depression, anxiety and fear in the experimental group were significantly different from those in the control group (P0.05), suggesting that the experimental group was accompanied by psychosomatic symptoms.
3, the evaluation of anxiety and depression in patients with occupational mercury poisoning: the SAS crude score of the experimental group was 29.43 and 15.24, the positive rate of SAS40 was 12.41% (18/145 cases), the SAS crude score of the control group was 26.10 soil 11.55, the difference of SAS40 positive rate 3.39% (2/59 cases) was significant (P0.05). The experimental group SDS crude score was 31.29 13.32, and the difference of SDS coarse 26.51 of the control group was significantly different from the same period of the same period. The positive rate of SDS40 in the experimental group (P0.05) was 3.39% (10/145 cases), and the positive rate of SDS40 in the control group was 56.90% (4/59 case), the difference was not significant (P0.05). It showed that the occupational mercury poisoning patients had emotional disorder and the anxiety was more prominent.
4, the sleep condition of the patients with occupational mercury poisoning: the 3 factors of sleep quality, sleep disorder and daytime dysfunction and the total score of PsQI in the experimental group were significantly different from those in the control group (P0.05), but there was no significant difference between 4 factors of sleep time, sleep time, sleep efficiency and hypnotic drugs (P0.05). The patients with occupational mercury poisoning had abnormal sleep with some factors compared with the control group.
5, analysis of the effects of anxiety and depression on the sleep of patients with occupational mercury poisoning: 125 patients with occupational mercury poisoning without anxiety and depression were compared with the control group in sleep quality, sleep disorder, day dysfunction 3 factors and PSQI, total score difference (P0.05), while sleep time, sleep time, sleep efficiency, hypnotic drug 4 factors and control groups Compared with the control group, there were 6 factors in sleep quality, sleep time, sleep efficiency, sleep disorder, sleep time, and PSQI, and the total scores were different (P0.05) in sleep quality, sleep time, sleep time, and PSQI (P0.05). There was no difference in hypnotics (P0.05). Patients with occupational mercury poisoning associated with anxiety and depression were no more than those in the control group. Anxiety and depression of occupational mercury poisoning patients compared sleep quality, sleep time, sleep time, sleep efficiency, sleep disorders, daytime dysfunction, hypnotic drugs all 7 factors and PSQI, total score, there are differences (P0.05).
Conclusion:
1. Occupational mercury poisoning patients have emotional disorders such as anxiety and depression.
2. Occupational mercury poisoning patients have abnormal sleep, mainly manifested in sleep quality, sleep disorders, day dysfunction three factors and PSQI. total score abnormalities.
3. Anxiety and depression may aggravate the sleep disorder of occupational mercury poisoning patients.
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R135
【參考文獻(xiàn)】
相關(guān)期刊論文 前10條
1 金龍金,樓哲豐,董杰影,陳錫文;汞、鎘對(duì)小鼠離體骨髓細(xì)胞和睪丸生殖細(xì)胞的DNA損傷作用[J];癌變.畸變.突變;2004年02期
2 賴小希,方國(guó)祥;慢性汞接觸者腎功能指標(biāo)的變化[J];湖北預(yù)防醫(yī)學(xué)雜志;2001年01期
3 劉蘋,李健,吳錫南,納冬荃;甲基汞對(duì)親仔兩代大鼠的神經(jīng)行為毒性效應(yīng)[J];環(huán)境與健康雜志;2001年06期
4 湯慶合,丁振華,王文華,劉彩娥,黃仁華,王海瑾;不同垃圾填埋單元土壤——植物系統(tǒng)中汞的污染和遷移[J];上海環(huán)境科學(xué);2003年11期
5 李潔雅;郭偉;曹建霞;;汞中毒類精神分裂癥2例報(bào)告[J];中國(guó)工業(yè)醫(yī)學(xué)雜志;2009年05期
6 郭麗,畢曉穎,李志超,張春霞,凌翎,陳強(qiáng);甲基汞對(duì)腦神經(jīng)膠質(zhì)細(xì)胞凋亡及c-fos表達(dá)的影響[J];衛(wèi)生研究;2002年01期
7 王麗,賈光;甲基汞的發(fā)育毒性及其研究進(jìn)展[J];衛(wèi)生研究;2005年05期
8 李勇,潘漪清,朱惠剛;氯化甲基汞激發(fā)程序性細(xì)胞死亡與胚胎神經(jīng)系統(tǒng)發(fā)育的關(guān)系探討[J];衛(wèi)生研究;1998年04期
9 李樹強(qiáng),趙金垣;汞在腎臟內(nèi)代謝的研究進(jìn)展[J];中國(guó)職業(yè)醫(yī)學(xué);2002年02期
10 石龍,孫志偉,劉曉梅,袁智敏,徐靜,韓金榮,王忠偉;甲基汞對(duì)小鼠淋巴細(xì)胞程序外DNA合成的影響[J];中國(guó)公共衛(wèi)生;2003年07期
，本文編號(hào)：2174398
本文鏈接：http://sikaile.net/yixuelunwen/yufangyixuelunwen/2174398.html
最近更新
教材專著
