長(zhǎng)期應(yīng)用質(zhì)子泵抑制劑可能增加癡呆發(fā)生風(fēng)險(xiǎn)的研究現(xiàn)狀
發(fā)布時(shí)間:2018-11-15 08:21
【摘要】:質(zhì)子泵抑制劑(PPI)是臨床常用抑酸藥,主要用于消化性潰瘍、卓-艾綜合征、胃食管反流病及根治幽門(mén)螺桿菌等。長(zhǎng)期使用PPI可引起多種不良反應(yīng),還可能增加癡呆發(fā)生風(fēng)險(xiǎn),其機(jī)制尚不清楚。此文就PPI與癡呆的相關(guān)性及其可能機(jī)制做一綜述。
[Abstract]:Proton pump inhibitor (PPI) is a commonly used acid suppressant in clinic. It is mainly used in peptic ulcer, Zhuo Ai syndrome, gastroesophageal reflux disease and radical cure of Helicobacter pylori. Long-term use of PPI can cause multiple adverse reactions and may increase the risk of dementia, its mechanism is unclear. This paper reviews the relationship between PPI and dementia and its possible mechanism.
【作者單位】: 浙江大學(xué)附屬第一醫(yī)院消化內(nèi)科;
【分類(lèi)號(hào)】:R975.2
本文編號(hào):2332730
[Abstract]:Proton pump inhibitor (PPI) is a commonly used acid suppressant in clinic. It is mainly used in peptic ulcer, Zhuo Ai syndrome, gastroesophageal reflux disease and radical cure of Helicobacter pylori. Long-term use of PPI can cause multiple adverse reactions and may increase the risk of dementia, its mechanism is unclear. This paper reviews the relationship between PPI and dementia and its possible mechanism.
【作者單位】: 浙江大學(xué)附屬第一醫(yī)院消化內(nèi)科;
【分類(lèi)號(hào)】:R975.2
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