【摘要】：目的:采用離子色譜法測定羥乙基淀粉中乙二醇殘留。方法:色譜柱為Ultra AQ C18(250 mm×4.6 mm,5μm),流動相為純化水,流速為1.0 m L·min-1,柱后衍生溶液為1.5 mol·L-1氫氧化鈉,流速為0.2m L·min-1,電化學檢測器(安培檢測器,金電極,Ag/Ag Cl參比電極,糖標準四電位波形)。結(jié)果:建立了用離子色譜峰高定量法測羥乙基淀粉中乙二醇殘留的方法。在0.4~4.0μg·m L-1濃度范圍內(nèi)峰高線性關(guān)系良好,相關(guān)系數(shù)r=0.999 1,RSD為2.4%,最低檢測限為15 ng·m L-1。結(jié)論:所建方法簡便、準確、可操控性強。
[Abstract]:Objective: to determine ethylene glycol residues in hydroxyethyl starch by ion chromatography. Methods: the chromatographic column consisted of Ultra AQ C18 (the mobile phase of 250 mm 脳 4.6 mm,5 渭 m), was purified water, the flow rate was 1.0 mL min-1, the derivative solution was 1.5 mol L-1 sodium hydroxide, and the flow rate was 0.2m L min-1, electrochemical detector (amperometric detector, gold electrode, Ag/Ag Cl reference electrode, standard potential waveform of sugar). Results: a method for the determination of ethylene glycol residues in hydroxyethyl starch by ion chromatography was established. The linear relationship of peak height was good in the concentration range of 0.4 渭 g mL ~ (-1), the correlation coefficient was 0.999 ~ (-1) (RSD = 2.4), and the lowest detection limit was 15 ng mL ~ (-1). Conclusion: the method is simple, accurate and operable.
【作者單位】： 中國食品藥品檢定研究院;賽默飛世爾科技中國有限公司;
【分類號】：R927;O657.3

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1 張亦農(nóng),劉欣,吳侔天,張長久;氣相色譜-質(zhì)譜法檢測人尿中的羥乙基淀粉[J];質(zhì)譜學報;2003年04期

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本文編號：2280382