本文關(guān)鍵詞：中藥歸經(jīng)研究的現(xiàn)狀及“穴藥”法的提出，由筆耕文化傳播整理發(fā)布。

中藥歸經(jīng)研究的現(xiàn)狀及“穴藥”法的提出

Status of reaching meridian research for Chinese matria medica and to raise ＂point-medicine＂ method

[1] [2]

DENG Kai-wen , HE Fu-yuan （ 1. The First Affinity Hospital, Hunan University of Chinese Medicine, Changsha 410007, China ; 2. Department of Pharmaceutics , Hunan Universi

[1]湖南中醫(yī)藥大學(xué)第一附屬醫(yī)院,湖南長沙410007; [2]湖南中醫(yī)藥大學(xué)藥學(xué)院,中藥藥性與藥效國家中醫(yī)藥管理局重點實驗室,現(xiàn)代中藥制劑制備技術(shù)與評價實驗室,湖南長沙410208

文章摘要：目的：分析中藥歸經(jīng)研究的現(xiàn)狀，提出并闡明“穴藥”法的中藥歸經(jīng)研究法。方法：對中藥有效成分群（物）的歸經(jīng)及與經(jīng)絡(luò)臟腑功能（象）的互應(yīng)關(guān)系的研究現(xiàn)狀進行剖析，找出其不足與解決問題的對策。結(jié)果：特定的中藥成分群對特定的經(jīng)絡(luò)臟腑有選擇性的作用，這是中藥歸經(jīng)的物質(zhì)基礎(chǔ)，體現(xiàn)“物”性；經(jīng)絡(luò)臟腑的功能狀態(tài)以-定的證候表現(xiàn)出來，體現(xiàn)“象”性，一定功能的經(jīng)絡(luò)臟腑對特征中藥成分群有反作用，可用于探知和表征經(jīng)絡(luò)臟腑，體現(xiàn)“候”性，三者實為“物-象-候”印跡關(guān)系。經(jīng)絡(luò)臟腑功能狀態(tài)也可通過針刺特異腧穴改變，而這種改變可以通過中藥定量藥理學(xué)參數(shù)表征，據(jù)此可建立中藥歸經(jīng)研究的“穴藥”新方法，也可以探討中藥成分與病證網(wǎng)絡(luò)靶點的關(guān)系，起到-箭雙雕的作用。結(jié)論：中藥與經(jīng)絡(luò)臟腑及其功能三者互為“物-象-候”印跡關(guān)系，可通過針刺特異性腧穴改變，“穴藥”法既是中藥歸經(jīng)研究最簡捷的方法，，也是探知經(jīng)絡(luò)臟象重要方法。

Abstr：Objective： To analyze the status of reaching meridian research for the Chinese Matria Medica and to raise point- medicine method. Method： To review and analyze the studied situation of the corresponding relationships between ＂materials＂ , as the constituents in the Chinese materia medica（CMM） as reaching meridian material foundation, and ＂ image＂ , as the function states of the zang-fu viscera, to investigate the problems and the measures to solve it. Result： There are imprinting relationships among ＂materi- als＂ , as the constituents alike metabolic pathway in the CMM as reaching meridian material foundation, and ＂image＂ , as the function of the zang-fu viscera related with meridians, and ＂symptom＂ , the states of them, retroacted, represented and explored by the corre- sponding meridianed constituents in the CMM as quantitative pharmacologic parameters, also modified by special acupuncture points, fi- nally to establish the new method of reaching meridian according to meridian point-medicine action and also to investigate the relations between the constituents in the CMM and network targets of disease as to kill two birds with one arrow. Conclusion： There are imprint- ing relationships among ＂materials＂ , ＂image＂ , ＂symptom＂ versus CMM, zang-fu viscera function related with meridians, their func- tion status respectively, which are modified by acupuncture merisian points. The point-medicine method for assuring reaching meridian is the most simple way to investigate reaching meridian for CMM,is also a important way to investigate visceral and meridianal manifestations.

文章關(guān)鍵詞：

Keyword：:reaching meridian for Chinese materia medica viscera and meridian visceral manifestations syndrome ＂materi- als＂ -＂ image＂ -＂ symptom＂ network pharmacology topologic network network chromatopharmacody

課題項目：國家自然科學(xué)基金項目（81073142,81173558）;國家教育部博士點基金項目（20104323110002）

  本文關(guān)鍵詞：中藥歸經(jīng)研究的現(xiàn)狀及“穴藥”法的提出，由筆耕文化傳播整理發(fā)布。