本文選題：萬古霉素 + 血藥濃度�。� 參考：《中國臨床藥理學(xué)雜志》2015年22期

【摘要】：目的探討自制萬古霉素質(zhì)控血清在血藥濃度監(jiān)測中應(yīng)用的可行性。方法取注射用鹽酸萬古霉素1.0 mg,注射用水溶解后加入血清基質(zhì)液,制備質(zhì)量濃度分別為10,20,30μg·m L-1的萬古霉素質(zhì)控血清并檢測其濃度,考察方法準確性、質(zhì)控樣品的穩(wěn)定性及臨床應(yīng)用。結(jié)果自制低、中、高濃度的萬古霉素質(zhì)控血清檢測結(jié)果為靶值的98.0%~101.5%,-30℃保存6個月含量變化小于2%。結(jié)論自制萬古霉素質(zhì)控血清操作方法簡單、成本低、結(jié)果準確可靠,可以作為實驗室日常質(zhì)量控制。
[Abstract]:Objective to investigate the feasibility of using self-made vancomycin quality control serum in monitoring blood concentration. Methods Vancomycin hydrochloride 1.0 mg for injection was used to prepare vancomycin quality control serum with mass concentration of 10 ~ 2030 渭 g / m ~ (-1), and the accuracy of the method was investigated, and vancomycin hydrochloride was added into serum matrix solution after dissolution with water for injection. Stability and clinical application of quality control samples. Results the results of low, medium and high concentration vancomycin quality control serum were 98.0% of the target value. The content of vancomycin was stored at 101.5 鈩，

本文編號：2114047