發(fā)布時間：2018-07-03 04:20

  本文選題：不確定度評價 + pH測量　； 參考：《中國藥學雜志》2017年08期

【摘要】：目的對藥品中pH測定的不確定度進行評定。方法以葡萄糖氯化鈉注射液pH測定為例,分別采用基于不確定度傳播律(GUM)法和基于蒙特卡洛(MCM)法評定pH測定的不確定度,用MCM法驗證GUM法評定不確定度的可靠性。結果 GUM法和MCM法得到的測量結果以及不確定度基本一致。結論 MCM法用于不確定度評定,是一個簡便、可靠,且適用性更廣的可選擇方法。
[Abstract]:Objective to evaluate the uncertainty of pH determination in drugs. Methods the uncertainty of pH determination in glucose sodium chloride injection was evaluated by means of uncertainty propagation law (GUM) method and Monte Carlo method (MCM), and the reliability of gum method was verified by MCM method. Results the measurement results and uncertainty obtained by GUM method and MCM method were basically consistent. Conclusion MCM is a simple, reliable and more suitable method for uncertainty evaluation.
【作者單位】： 國家藥典委員會;江蘇省食品藥品監(jiān)督檢驗研究院;清華大學化學系;天津市藥品檢驗所;貴州省食品藥品檢驗所;
【分類號】：R927
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本文編號：2092371