我區(qū)5家醫(yī)療衛(wèi)生機(jī)構(gòu)實(shí)施《抗菌藥物臨床應(yīng)用管理辦法》前后抗菌藥物應(yīng)用分析
發(fā)布時(shí)間:2018-07-01 10:29
本文選題:抗菌藥物 + 用藥頻度; 參考:《中國(guó)藥房》2015年17期
【摘要】:目的:評(píng)價(jià)我區(qū)5家醫(yī)療衛(wèi)生機(jī)構(gòu)實(shí)施《抗菌藥物臨床應(yīng)用管理辦法》的效果。方法:調(diào)取《抗菌藥物臨床應(yīng)用管理辦法》(以下簡(jiǎn)稱(chēng)"《辦法》")實(shí)施前(2010-2011年)、實(shí)施后(2012-2013年)上海市閘北區(qū)5家醫(yī)療衛(wèi)生機(jī)構(gòu)抗菌藥物應(yīng)用數(shù)據(jù),采用Excel對(duì)用藥頻度(DDDs)進(jìn)行統(tǒng)計(jì)分析。結(jié)果:《辦法》實(shí)施后5家醫(yī)療衛(wèi)生機(jī)構(gòu)抗菌藥物總DDDs下降29.75%,門(mén)診和住院患者特殊使用級(jí)抗菌藥物DDDs分別下降100%和27.91%;《辦法》實(shí)施后門(mén)診患者氨基糖苷類(lèi)DDDs較實(shí)施前下降68.26%,住院患者喹諾酮類(lèi)和氨基糖苷類(lèi)DDDs較實(shí)施前下降26.88%、22.20%;《辦法》實(shí)施后5家醫(yī)療衛(wèi)生機(jī)構(gòu)門(mén)診和住院患者抗菌藥物使用率等應(yīng)用指標(biāo)均已達(dá)標(biāo),其中Ⅸ類(lèi)切口手術(shù)預(yù)防使用抗菌藥物比例、預(yù)防使用抗菌藥物時(shí)間≤24 h的比例、抗菌藥物使用強(qiáng)度這3項(xiàng)應(yīng)用指標(biāo)趨于好轉(zhuǎn),與《辦法》實(shí)施前相比,差異有統(tǒng)計(jì)學(xué)意義(P0.01)。結(jié)論:《辦法》的頒布對(duì)抗菌藥物的使用起到了一定的指導(dǎo)和制約作用,但Ⅸ類(lèi)切口手術(shù)預(yù)防使用抗菌藥物以及抗菌藥物使用強(qiáng)度距離達(dá)標(biāo)尚有差距。
[Abstract]:Objective: to evaluate the effect of clinical application of antimicrobial drugs in 5 medical and health institutions in our area. Methods: the data of antimicrobial application in 5 medical and health institutions in Zhabei District, Shanghai, were collected before (2010-2011) and after (2012-2013) the "Management measures for Clinical Application of Antibacterial drugs" (hereinafter referred to as "the methods"). The DDDs were statistically analyzed by Excel. Results: after implementation, the total DDDs of antimicrobial agents in 5 medical and health institutions decreased 29.75%, and the DDDs of special use class of outpatients and inpatients decreased by 100% and 27.91%, respectively, and the aminoglycoside DDDs of outpatients after implementation were lower than those before implementation. The quinolones and aminoglycosides DDDs of inpatients decreased 26.88 and 22.20, and the utilization rate of antimicrobial drugs in outpatients and inpatients of 5 medical and health institutions reached the standard after the implementation. The ratio of prophylactic use of antimicrobial agents and the proportion of prophylactic use time of antimicrobial agents 鈮,
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