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利巴韋林在兒科臨床應用的安全性評價

發(fā)布時間:2018-06-21 09:17

  本文選題:利巴韋林 + 兒科; 參考:《國際藥學研究雜志》2016年04期


【摘要】:利巴韋林為人工合成的核苷類抗病毒藥,體外具有抑制呼吸道合胞病毒、流感病毒、甲型肝炎病毒、腺病毒等多種病毒生長的作用,其機制不全清楚。本文通過檢索萬方醫(yī)學網(wǎng)、中國醫(yī)院數(shù)字圖書館、醫(yī)知網(wǎng)、中美兩國食品藥品監(jiān)督管理相關網(wǎng)站數(shù)據(jù)庫(CFDA、FDA、Daily Med)和中國藥品注冊數(shù)據(jù)庫等,了解當前利巴韋林的藥品信息及臨床應用現(xiàn)狀;根據(jù)國內外利巴韋林的藥品信息及報道的兒童臨床應用情況,結合我院兒科臨床應用的現(xiàn)狀,對其安全性進行評價,促進其合理應用,并對中國利巴韋林制劑的規(guī)范化管理提出建議。
[Abstract]:Ribavirin is a synthetic nucleoside antiviral drug, which can inhibit the growth of respiratory syncytial virus, influenza virus, hepatitis A virus, adenovirus and so on in vitro. The mechanism of ribavirin is unclear. By searching Wanfang Medical Network, the Digital Library of Chinese Hospitals, the Medical knowledge Network, the website database of food and drug supervision and administration in China and the United States, CFDAF FDAU Daily Medand China Drug Registration Database, etc. To understand the current drug information and clinical application of ribavirin, to evaluate the safety of ribavirin according to the clinical application of ribavirin at home and abroad, combined with the present situation of pediatric clinical application in our hospital. To promote the rational application of ribavirin in China and put forward suggestions for standardized management of ribavirin preparation.
【作者單位】: 山西省兒童醫(yī)院藥劑科;山西醫(yī)科大學藥學院;
【基金】:國家衛(wèi)生計生委藥政司委托課題 山西省衛(wèi)生廳科研課題資助項目(201301042)
【分類號】:R985
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本文編號:2048040

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