本文選題：洛索洛芬銀乳膏 + 洛索洛芬銀��； 參考：《中國(guó)藥房》2017年06期

【摘要】：目的:建立測(cè)定洛索洛芬銀乳膏中洛索洛芬銀含量的方法,為該制劑的質(zhì)量控制提供參考。方法:采用高效液相色譜法。色譜柱為Diamonsil C_(18),流動(dòng)相為甲醇-水-冰醋酸-三乙胺(55∶45∶0.1∶0.1,V/V/V/V),流速為1.0 m L/min,檢測(cè)波長(zhǎng)為223nm,柱溫為30℃,進(jìn)樣量為20μL。結(jié)果:洛索洛芬銀檢測(cè)質(zhì)量濃度線性范圍為6.53~130.7μg/m L(r=0.999 9);定量限為0.253μg/m L,檢測(cè)限為0.076μg/m L;精密度、穩(wěn)定性、重復(fù)性試驗(yàn)的RSD2%;加樣回收率為96.79%~103.68%(RSD=2.23%,n=9)。結(jié)論:該方法操作方便、結(jié)果準(zhǔn)確、重復(fù)性好,可用于洛索洛芬銀乳膏中洛索洛芬銀的含量測(cè)定。
[Abstract]:Objective: to establish a method for the determination of losuprofen silver in iosoprofen silver cream and to provide reference for its quality control. Methods: high performance liquid chromatography was used. The mobile phase was methanol-water-glacial acetic acid-triethylamine (55: 45: 0.1) V / V / V / V / V / V / V / V / V / V / V / V / V / V _ (1). The flow rate was 1.0 mL / min, the detection wavelength was 223 nm, the column temperature was 30 鈩，

本文編號(hào)：1953609