本文選題：高效毛細管電泳 + 手性拆分��； 參考：《南開大學(xué)學(xué)報(自然科學(xué)版)》2017年01期

【摘要】：以羧甲基-β-CD(CM-β-CD)為手性添加劑,用毛細管區(qū)帶電泳法對氫化安息香和聯(lián)萘酚磷酸酯的消旋體進行了拆分研究.實驗考察了CM-β-CD的濃度、背景電解質(zhì)的p H值、分離電壓對對映體分離的影響.結(jié)果表明,以100 mmol/L Tris-磷酸為緩沖液,CM-β-CD的濃度在5-30 mg/m L,p H值7.5-10.0之間,電壓在10-30 k V之間,溫度在25℃時,氫化安息香和聯(lián)萘酚磷酸酯均能獲得基線分離.該方法簡便、快速、分離范圍寬,可用于氫化安息香和聯(lián)萘酚磷酸酯的手性分離.
[Abstract]:The resolution of racemates of hydrogenated benzoin and binaphthol phosphate was studied by capillary zone electrophoresis with carboxymethyl- 尾 -CD-CD-CM- 尾 -CD as chiral additive. The effects of concentration of CM- 尾 -CD, pH value of background electrolyte and separation voltage on enantiomeric separation were investigated. The results show that when the concentration of CM- 尾 -CD in 100 mmol/L Tris-phosphoric acid buffer is between 7.5 and 10.0 for 5-30 mg/m, the voltage is between 10-30 kV and the temperature is 25 鈩，

本文編號：1939023