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Ⅰ類切口圍手術(shù)期預(yù)防性使用抗菌藥物干預(yù)分析

發(fā)布時(shí)間:2018-05-23 07:40

  本文選題:Ⅰ類手術(shù)切口 + 圍手術(shù)期 ; 參考:《中華醫(yī)院感染學(xué)雜志》2015年13期


【摘要】:目的研究經(jīng)全國(guó)抗菌藥物臨床應(yīng)用專項(xiàng)整治以及等級(jí)醫(yī)院評(píng)審的藥學(xué)干預(yù)后乳腺、甲狀腺手術(shù)、腹股溝疝修補(bǔ)術(shù)3種Ⅰ類切口手術(shù)圍術(shù)期預(yù)防性使用抗菌藥物的合理性。方法隨機(jī)選取2010年7-12月和2013年7-12月3種手術(shù)Ⅰ類切口病歷各100份,對(duì)圍手術(shù)期預(yù)防性抗菌藥物的使用率、選用藥物品種、給藥時(shí)機(jī)、用藥持續(xù)時(shí)間及傷口愈合等進(jìn)行對(duì)比。結(jié)果 3種Ⅰ類切口手術(shù)抗菌藥物使用率由干預(yù)前的99.3%降至干預(yù)后12.0%,乳腺手術(shù)、甲狀腺手術(shù)、疝氣手術(shù)的抗菌藥物使用率分別由干預(yù)前的98.0%、100.0%、100.0%,降至干預(yù)后的16.0%、11.0%、9.0%;合理應(yīng)用率高達(dá)91.0%;整改后的300例患者無切口感染,并且切口甲級(jí)愈合占98.3%;Ⅰ類切口手術(shù)預(yù)防用抗菌藥物的用藥品種,由2010年的三代頭孢菌素使用率62.3%改進(jìn)為2013年的一代頭孢菌素的使用率88.9%,并且杜絕了無依據(jù)的更換藥品。結(jié)論藥學(xué)干預(yù)與行政干預(yù)顯著降低了Ⅰ類切口手術(shù)抗菌藥物預(yù)防性使用率,提高了抗菌藥物使用的合理率。
[Abstract]:Objective to study the rationality of prophylactic use of antimicrobial agents in breast, thyroid surgery and inguinal herniorrhaphy after clinical treatment of antimicrobial agents in China and the pharmacological intervention evaluated by grade hospitals during perioperative period. Methods A total of 100 medical records of three types of surgical incision were randomly selected from July to December 2010 and from July to December 2013 respectively. The utilization rate of prophylactic antimicrobial agents during perioperative period, the choice of drugs, the timing of administration, the duration of medication and wound healing were compared. Results the utilization rate of antibiotics decreased from 99.3% before intervention to 12.0% after intervention. The utilization rate of antibiotics in hernia surgery was reduced from 98.0 / 100.0g / 100.0g before intervention to 16.0 / 11.0/ 9.0after the intervention, and the reasonable application rate was as high as 91.0 / 91.The 300 patients after the correction had no incisional infection. The rate of utilization of cephalosporins in the third generation of cephalosporins in 2010 was improved from 62.3% to 88.9% in 2013, and the unwarranted replacement of drugs was eliminated. Conclusion Pharmacological intervention and administrative intervention can significantly reduce the prophylactic utilization rate of antimicrobial agents and increase the rational rate of use of antibiotics in class 鈪,

本文編號(hào):1923854

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