本文選題：阿立哌唑 + 不良反應(yīng)�。� 參考：《中國藥房》2015年03期

【摘要】：目的:探討阿立哌唑致不良反應(yīng)(ADR)的一般規(guī)律和特點(diǎn),為臨床合理用藥提供參考。方法:檢索2002-2013年我國醫(yī)藥期刊報(bào)道的阿立哌唑致ADR病例,并就收集到的67例ADR相關(guān)信息進(jìn)行分類、統(tǒng)計(jì)和分析。結(jié)果:阿立哌唑致ADR與性別無關(guān),多發(fā)生于20~39歲;用藥6個(gè)月內(nèi)ADR發(fā)生率較高;以神經(jīng)系統(tǒng)及心血管系統(tǒng)損害較為多見。66例患者均恢復(fù)正常,1例患者因Ⅲ度房室傳導(dǎo)阻滯未恢復(fù)正常。結(jié)論:盡管阿立哌唑安全性和耐受性均較好,但臨床仍需高度重視用藥監(jiān)測(cè),以減少ADR的發(fā)生,確保用藥安全。
[Abstract]:Objective: to study the general rule and characteristics of ADR induced by aripiprazole and to provide reference for rational drug use. Methods: a total of 67 cases of ADR caused by aripiprazole from 2002 to 2013 were searched for classification, statistics and analysis. Results: the incidence of ADR caused by aripiprazole was not related to sex, most occurred in 20 to 39 years old, and the incidence of ADR was higher within 6 months after treatment. Among them, the damage of nervous system and cardiovascular system was more common in 66 patients. One patient did not return to normal because of the third degree atrioventricular block. Conclusion: although aripiprazole is safe and tolerant, it is necessary to attach great importance to drug monitoring in order to reduce the incidence of ADR and ensure the safety of drug use.
【作者單位】： 河池市復(fù)退軍人醫(yī)院;河池市第四人民醫(yī)院藥劑科;
【分類號(hào)】：R971

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本文編號(hào)：1908127